Polydopamine loaded Oxidized Matrine
Polydopamine loaded Oxidized Matrine
Polydopamine can improve the solubility and stability of oxidized matrine, enhancing its therapeutic efficacy. The PDA(Polydopamine) layer can also facilitate targeted delivery to specific tissues or cells, especially when combined with targeting ligands (like antibodies or peptides).The use of polydopamine could allow for controlled release of oxidized matrine, providing sustained therapeutic effects while minimizing side effects.Given anti-cancer of matrine properties,a PDA-loaded oxidized matrine system could synergistically enhance the effects of existing cancer treatments by providing localized delivery and increased cytotoxicity against cancer cells.Polydopamine has photothermal properties,which can be utilized for photothermal therapy when combined with oxidized matrine. This dual approach can target tumor cells while also applying thermal treatment.