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R-XASYS-00250 4-oxo-2-Nonenal-d3,cas:1313400-91-7 4-oxo-2-Nonenal-d3 (4-ONE-d3)(C9H11D3O2,157.2) contains three deuterium atoms at the terminal methyl position. It is intended for use as an internal standard for the quantification of 4-ONE (Item No. 10185) by GC- or LC-mass spectrometry (MS). 4-ONE is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids. price>
R-R-0250 NH2-PEG3-CH2COOtBu Cas 189808-70-6 NH2-PEG3-CH2COOtBu/Cas 189808-70-6/Amino-PEG3-CH2CO2-t-butyl ester from ruixi. Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. price>
R-Mcs-250 DOPS:DOPC:Chol:DPPE-N-(6-azidohexanoyl) (ammonium salt)-Cyanine 5 lipid-Azide DOPS:DOPC:Chol:DPPE-N-(6-azidohexanoyl) (ammonium salt)(20:49:30:1molar ratio)-based Fluoroliposome Cyanine 5 lipid-Azide can be utilized for in vivo or in vitro imaging studies, enabling tracking of liposomes and associated compounds using fluorescence microscopy or other imaging techniques.The targeted delivery of drugs or other therapeutic agents can be enhanced through the use of DOPS and the bioorthogonal azide functionality for selective targeting. price>
R-XASYS-00251 CPI-613,cas:95809-78-2 CPI-613(C22H28O2S2,388.6) is a lipoic acid analog that inhibits α-ketoglutarate dehydrogenase, particularly in tumor cells.At 60-240 µM, CPI-613 induces a strong mitochondrial burst of reactive oxygen species, resulting in cell death. price>
R-R-0251 Aspergillus niger disaccharide Aspergillus niger is a type of fungus that is commonly found in nature and has been extensively studied for its ability to produce a wide range of enzymes and metabolites. The ability of Aspergillus niger to metabolize disaccharides plays a crucial role in its ecological niche as it allows the fungus to efficiently utilize available carbon sources for growth and survival. Additionally, this metabolic capability has been harnessed in various industrial applications, such as the production of enzymes, organic acids, and other valuable products through fermentation processes. price>
R-Mcs-251 DOPS:DOPC:Chol:DPPE-N-(6-azidohexanoyl) (ammonium salt)-Cyanine 5.5 lipid-Azide DOPS:DOPC:Chol:DPPE-N-(6-azidohexanoyl) (ammonium salt)(20:49:30:1molar ratio)-based Fluoroliposome Cyanine 5.5 lipid-Azide can be effectively utilized in various biomedical applications, including imaging and drug delivery. The unique fluorescent properties can be utilized for live-cell imaging, allowing researchers to track liposome distribution and dynamics in real-time. The enhanced azide functionality can enable targeted delivery of therapeutic agents through bioorthogonal reactions. Use in fluorescent assays for disease diagnostics, particularly in targeted detection of biomarkers. price>
R-XASYS-00252 4-hydroxy Hexenal-d3,cas:148706-05-2 4-hydroxy Hexenal-d3(C6H7D3O2,117.2) contains three deuterium atoms at the 6, 6, and 6 positions. It is intended for use as an internal standard for the quantification of 4-hydroxy hexenal by GC- or LC-mass spectrometry. price>
R-R-0252 5-Thio-D-Glucose CAS 20408-97-3 5-Thio-D-glucose is a thiosugar hexokinase inhibitor. It acts as a potent, competitive inhibitor of the cellular transport of D-glucose and D-glucose mediated insulin release. Thus, 5-Thio-D-glucose can be utilized to control/reduce the rate of glycolysis. It also functions as an inhibitor of spermatogenesis. price>
R-Mcs-252 DOPS:DOPC:Chol:DPPE-N-(6-azidohexanoyl) (ammonium salt)-Cyanine 7 lipid-Azide DOPS:DOPC:Chol:DPPE-N-(6-azidohexanoyl) (ammonium salt)(20:49:30:1molar ratio)-based Fluoroliposome Cyanine 7 lipid-Azide can be utilized for various cutting-edge applications in biological research, targeting, and imaging. The use of Cyanine 7, with its advantageous optical properties in the near-infrared spectrum, allows deep tissue imaging and tracking of liposome behavior in biological systems. Utilizing the azide functionality allows for bioorthogonal click chemistry reactions, which can enable the targeting of drugs or therapeutic agents to specific cells or tissues. Fluorescent Probes for Diagnostics: These liposomes can be employed in diagnostic assays, enabling sensitive detection of biological markers through fluorescence. price>
R-XASYS-00253 A1-Phytoprostane-I,cas:1035557-09-5 A1-Phytoprostane-I(C18H28O4,308.4) is a cyclopentenone isoprostane produced by the action of reactive oxygen species on α-linolenic acid in plants.There are two A1-phytoprostanes, both having the single ketone group on the ring structure. price>
R-R-0253 Mal-PEG12-NHS CAS: 756525-92-5 Mal-PEG12-NHS/CAS: 756525-92-5/ alpha-Maleimidopropionyl-oMega-succinimidyl-12(ethylene glycol) from ruixi. A heterobifunctional linker containing a maleimide moiety for sulfhydryl conjugation and an NHS activated ester with a spacer of PEG12. price>
R-Mcs-253 L-alpha-PC:Chol:DOPE-N-DBCO(69:30:1molar ratio)-Neutral Fluoroliposome DiA-DBCO L-alpha-PC:Chol:DOPE-N-DBCO(69:30:1molar ratio)-Neutral Fluoroliposome DiA-DBCO is a sophisticated system potentially used in biomedical research or clinical applications, especially in the realms of targeted therapeutics or imaging. The DBCO moieties can be used to chemically conjugate therapeutic agents or targeting ligands (e.g., antibodies) to the liposomes, enhancing specificity for certain cell types or tissues. The incorporation of DiA enables visual tracking of liposomes in biological systems, useful for studying biodistribution, therapeutic efficacy, or cellular uptake. price>
R-XASYS-00254 Piericidin A,cas:2738-64-9 Piericidin A(C25H37NO4,415.6) is an irreversible inhibitor of mitochondrial complex I that strongly associates with ubiquinone binding sites in both mitochondrial and bacterial forms of the enzyme. price>
R-R-0254 2-Azido-2-deoxy-D-glucose CAS 56883-39-7 2-Azido-2-deoxy-D-glucose has been used to study the substrate specificity of galactokinase. 2-Azido-2-deoxy-D-glucose is the azido analogue of D-glucosamine and may be used as a metabolic chemical reporter by direct labelling of glycans. The azide group is used to link to a fluorescent marker, enabling secondary visualisation and identification of glycoproteins. The azide moiety of 2-azido-2-deoxy-D-glucose has been used to form triazoles via a 1,3-dipolar cycloaddition reaction in the synthesis of molecules with improved solubility used to inhibit p38a MAPK for anti-inflammation. price>
R-Mcs-254 L-alpha-PC:Chol:DOPE-N-DBCO(69:30:1molar ratio)-Neutral Fluoroliposome DiD-DBCO L-alpha-PC:Chol:DOPE-N-DBCO(69:30:1molar ratio)-Neutral Fluoroliposome DiD-DBCO can be used for basic research to investigate cellular processes, drug interactions, and therapeutic outcomes as they can be tracked and monitored via fluorescence. The formulation could also be adapted for vaccine delivery, using the liposomes to encapsulate antigens and enhance their immunogenicity. This formulation can be engineered to attach various drugs or targeting moieties (such as antibodies or peptides) to liposomes via the DBCO reaction. This can enhance the specificity of drug delivery to target cells or tissues. DiD provides a way to visually track the liposomes within biological systems, making this formulation useful for studying biodistribution, cellular uptake, and therapeutic efficacy. price>
R-XASYS-00255 Sanguinarine (chloride),cas:5578-73-4 Sanguinarine(C20H14NO4•Cl,367.8) is a benzylisoquinoline alkaloid isolated from plants belonging to the family Papaveraceae.It exhibits antimicrobial, anti-inflammatory, and anti-oxidant properties and demonstrates antiproliferative and pro-apoptotic effects in some cancer cell lines. price>
R-R-0255 1-O-Alpha-D-glucopyranosyl-D-fructose 1-O-Alpha-D-glucopyranosyl-D-fructose/Trehalulose/CAS 51411-23-5 is a sugar that is found in plants, animals, and fungi. It is a reaction product of glucose with the enzyme trehalase, which cleaves off two molecules of water to form one molecule of glucose and one molecule of trehalulose. Trehalulose has been shown to be an inhibitor of phosphofructokinase, an enzyme involved in glycolysis. This inhibition can be reversed by the addition of ATP or pyruvate kinase. Trehalulose also has been shown to inhibit the growth of cells by interfering with protein synthesis. Trehalulose may have biological functions including dietary uses as a replacement for sucrose or lactose due to its low calorie content and high level of sweetness. price>
R-Mcs-255 L-alpha-PC:Chol:DOPE-N-DBCO(69:30:1molar ratio)-Neutral Fluoroliposome DiI-DBCO L-alpha-PC:Chol:DOPE-N-DBCO(69:30:1molar ratio)-Neutral Fluoroliposome DiI-DBCO can be adapted for the delivery of genetic materials, taking advantage of ability of DOPE to facilitate membrane fusion, which is crucial for effective transfection. The DBCO moiety allows for the attachment of targeting ligands (e.g antibodies, peptides) to the liposomes, enhancing delivery specificity to target cells or tissues (such as cancer cells). Using DiI as a fluorescent marker, these liposomes can be tracked in vitro or in vivo. Researchers can visualize biodistribution, cellular uptake, and the overall pharmacokinetics of the liposomes. price>
R-XASYS-00256 QD-394,cas:2132411-21-1 QD-394(C19H19N5O2,349.4) is an inducer of reactive oxygen species (ROS) production.It induces lipid peroxidation, increases in intracellular accumulation of reactive oxygen species (ROS), and decreases in the reduced glutathione (GSH) to oxidized GSH (GSSG) ratio in MIA PaCa-2 pancreatic cancer cells. price>
R-R-0256 D-Fructose-6-phosphate CAS : 643-13-0 D-Fructose-6-phosphate/CAS : 643-13-0/Fructose-6-phosphate is an important intermediate in the metabolic pathways of both animals and plants. This molecule is derived from glucose and is an important starting point for the synthesis of other carbohydrates, such as glycogen and starch. The synthesis of fructose-6-phosphate takes place through the action of the enzyme, glucose-6-phosphate isomerase, which converts glucose-6-phosphate to fructose-6-phosphate. This reaction is important for the generation of energy in the body, as fructose-6-phosphate can be used in the production of ATP, the primary energy molecule for cells. price>