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R-Mcs-256 L-alpha-PC:Chol:DOPE-N-DBCO(69:30:1molar ratio)-Neutral Fluoroliposome DiO-DBCO The L-alpha-PC:Chol:DOPE-N-DBCO (69:30:1 molar ratio) - Neutral Fluoroliposome DiO-DBCO formulation represents a versatile and innovative liposomal system suitable for a range of biotechnological and pharmaceutical applications. The combination of neutral charge, bioorthogonal chemistry, and fluorescent labeling allows for significant flexibility in tailoring the liposomes for specific roles in research and clinical applications. price>
R-XASYS-00257 6-Formylpterin,cas:712-30-1 6-Formylpterin(C7H5N5O2,191.1) is an oxidized pterin produced by photolytic breakdown of folic acid.It binds to one of two active sites on XO nearly quantitatively and irreversibly and prevents the metabolism of other substrates at the second site. price>
R-R-0257 Fitc-Corn Starch FITC (fluorescein isothiocyanate) corn starch refers to corn starch labeled with fluorescent group FITC. FITC is a widely used green fluorescent dye that can bind to various molecules. The FITC labeling process typically involves a reaction between the isothiocyanate group of FITC and the nucleophilic group (such as amine or hydroxyl) on corn starch molecules. After successful conjugation, FITC labeled corn starch can be studied under a fluorescence microscope or used for other fluorescence assays. price>
R-Mcs-257 L-alpha-PC:Chol:DOPE-N-DBCO(69:30:1molar ratio)-Neutral Fluoroliposome DiR-DBCO L-alpha-PC:Chol:DOPE-N-DBCO(69:30:1molar ratio)-Neutral Fluoroliposome DiR-DBCO can be used in vaccine delivery systems, where they encapsulate antigens and help in inducing immune responses. The liposomes can encapsulate therapeutic agents, improving their solubility, stability, and bioavailability. The lipid composition supports effective delivery through biological barriers.The incorporation of fluorophores like DiR allows for non-invasive imaging in vivo. This is beneficial for studying the pharmacokinetics of liposomal formulations and their targeting to specific tissues or tumors.The bioorthogonal chemistry enabled by N-DBCO allows for precise functionalization of the liposomes with targeting ligands (e.g., antibodies, peptides) that can bind to specific cell types or disease markers. This enhances the efficacy and reduces the side effects of therapeutic agents. price>
R-XASYS-00258 7-Azido-4-methylcoumarin,cas:95633-27-5 7-Azido-4-methylcoumarin (AzMC)(C10H7N3O2,201.2) is a coumarin fluorescent probe for hydrogen sulfide (H2S).AzMC selectively fluoresces in the presence of H2S over a panel of reactive nitrogen, oxygen, and sulfur species. price>
R-R-0258 Blood Group A trisaccharide, N-aminoethyl nonanamide Blood Group A trisaccharide, N-aminoethyl nonanamide CAS 170298-33-6 from ruixi. Blood Group A trisaccharide refers to a specific sugar structure found on the surface of red blood cells in individuals with blood type A. N-aminoethyl nonanamide is a small molecule that contains an amine group (NH2) and an amide group (CONH2). price>
R-Mcs-258 L-alpha-PC:Chol:DOPE-N-DBCO(69:30:1molar ratio)-Neutral Fluoroliposome Dansyl lipid (headgroup)-DBCO L-alpha-PC:Chol:DOPE-N-DBCO(69:30:1molar ratio)-Neutral Fluoroliposome Dansyl lipid (headgroup)-DBCO can be designed for vaccine delivery, wherein they can encapsulate antigens and adjuvants, potentially enhancing the immunogenic response. L-alpha-PC:Chol:DOPE-N-DBCO(69:30:1molar ratio)-Neutral Fluoroliposome Dansyl lipid (headgroup)-DBCO serves as a platform for studying pharmacokinetics, therapeutic efficacy, and the safety of liposomal systems in clinical applications. These liposomes can encapsulate various therapeutic agents (chemotherapeutics, peptides, nucleic acids) and facilitate their delivery to target sites, improving efficacy and reducing side effects.Utilizing the fluorescent properties of the dansyl group, researchers can visualize and track liposomes in living organisms, assessing their biodistribution and cellular uptake mechanisms.The presence of DBCO allows for the conjugation of azide-functionalized compounds, such as targeting ligands or therapeutic agents. This feature is particularly useful in creating custom-targeted liposomes for specific applications.Dansyl lipids can be used to study lipid interactions and dynamics in membranes, providing insights into membrane fluidity, phase behavior, and interactions with proteins or drugs. price>
R-XASYS-00259 LysoFP-NO2,cas:69408-75-9 LysoFP-NO2(C18H17N3O5,355.3) is a turn-on fluorescent probe for carbon monoxide (CO) that localizes to the lysosome.In the presence of lysosomal CO, lysoFP-NO2 is transformed into lysoFP-NH2, which is highly fluorescent. price>
R-R-0259 Methyl 6-amino-deoxy-galactoyranoside CAS 5155-47-5 Methyl 6-Amino-6-deoxy-α-D-glucopyranoside is an intermediate in synthesizing Ranimustine (R120030), a nitrosourea alkylating agent approved in Japan for the treatment of chronic myelogenous leukemia and polycythemia vera. It can be used in biological study of synthesis of anti-EGFR antibody-drug conjugates. It can also be used in therapeutic use and biological study of BCMA (B-Cell Maturation Antigen) antigen binding proteins. price>
R-Mcs-259 L-alpha-PC:Chol:DOPE-N-DBCO-Neutral Fluoroliposome NBD lipid (fatty acid tail)-DBCO L-alpha-PC:Chol:DOPE-N-DBCO(69:30:1molar ratio)-Neutral Fluoroliposome NBD lipid (fatty acid tail)-DBCO serves as a platform for studying pharmacokinetics, therapeutic efficacy, and the safety of liposomal systems in clinical applications. These liposomes can encapsulate various therapeutic agents (chemotherapeutics, peptides, nucleic acids) and facilitate their delivery to target sites, improving efficacy and reducing side effects.Utilizing the fluorescent properties of the dansyl group, researchers can visualize and track liposomes in living organisms, assessing their biodistribution and cellular uptake mechanisms.The presence of DBCO allows for the conjugation of azide-functionalized compounds, such as targeting ligands or therapeutic agents. This feature is particularly useful in creating custom-targeted liposomes for specific applications. price>
R-XASYS-00260 Jacaric Acid,cas:28872-28-8 Jacaric acid(C18H30O2,278.4) is a conjugated polyunsaturated fatty acid first isolated from seeds of Jacaranda plants.Structurally, it is an 18-carbon ω-6 triene isomer of γ-linolenic acid. Jacaric acid induces cell cycle arrest and apoptosis in a variety of cancer cell lines (GI50 = 1-5 µM). price>
R-R-0260 CY5-catalase CY5-catalase refers to a conjugate formed by attaching the fluorescent dye CY5 to the enzyme catalase.By tagging catalase with CY5, researchers can track the activity, localization, and distribution of the enzyme within cells or tissues. This can provide insights into the behavior and function of catalase in different biological processes and can help study oxidative stress, cellular metabolism, and other related mechanisms. price>
R-Mcs-260 L-alpha-PC:Chol:DOPE-N-DBCO(69:30:1molar ratio)-Neutral Fluoroliposome NBD lipid (headgroup)-DBCO L-alpha-PC:Chol:DOPE-N-DBCO(69:30:1molar ratio)-Neutral Fluoroliposome NBD lipid (headgroup)-DBCO can effectively encapsulate both hydrophilic and hydrophobic drugs, allowing for targeted delivery. The stability provided by cholesterol and the fusogenic properties of DOPE enhance drug efficacy and uptake in target cells. The NBD label allows for easy tracking of the liposomes in live cells or animal models, making it ideal for studies in drug distribution, cellular uptake, and pharmacokinetics. The DBCO modification allows for selective conjugation with azide-containing molecules, enabling the attachment of targeting ligands, fluorescent tags, or therapeutic agents, making this platform versatile for personalized medicine. These liposomes can serve as carriers for antigens in vaccine formulations, aiding in presenting the antigens to the immune system while being tracked for efficacy. price>
R-XASYS-00261 8-Hydroxy-2-deoxyguanosine,cas:88847-89-6 8-Hydroxy-2-deoxyguanosine(C10H13N5O5,283.2) is produced by oxidative damage of DNA by reactive oxygen and nitrogen species, including hydroxyl radical and peroxynitrite. It serves as a measure of oxidative stress in biological systems. price>
R-R-0261 Biotin-berberine Biotin-berberine refers to a conjugate formed by attaching the vitamin biotin to the alkaloid compound berberine.Biotin-berberine conjugates can be used in techniques such as affinity chromatography, where the biotin moiety can be captured by avidin or streptavidin-coated surfaces, facilitating purification or isolation of berberine-binding proteins. They can also be utilized for fluorescence-based imaging studies, where the biotinylated berberine can be detected using avidin or streptavidin conjugated to fluorescent dyes. price>
R-Mcs-261 L-alpha-PC:Chol:DOPE-N-DBCO(69:30:1molar ratio)-Neutral Fluoroliposome Pyrene lipid (headgroup)-DBCO This is a neutral liposomal formulation composed predominantly of L-alpha-phosphatidylcholine and cholesterol, with a small percentage of DOPE-N-DBCO for bio-orthogonal click chemistry applications. The liposome is labeled with pyrene, a fluoresc ent moiety, on the lipid headgroup for imaging or tracking purposes. price>
R-XASYS-00262 Isoquercetin,cas:482-35-9 Isoquercetin(C21H20O12,464.4) is a flavonoid that has been isolated from A. venetum and has diverse biological activities, including antiviral, anti-apoptotic, and neuroprotective properties.It reduces viral titers of H5N1 influenza isolates by 79.66% in a plaque assay when used at a concentration of 1 ng/ml. price>
R-R-0262 Yeast glucan sulfate Yeast glucan sulfate is a modified form of the polysaccharide beta-glucan, which is a type of carbohydrate found in various sources, including yeast, mushrooms, and grains.Yeast glucan sulfate has also been studied for its potential therapeutic applications. For example, it has been evaluated as a potential treatment for fungal infections, asthma, and various inflammatory conditions. price>
R-Mcs-262 L-alpha-PC:Chol:DOPE-N-DBCO-Neutral Fluoroliposome Rhodamine lipid (headgroup)-DBCO L-alpha-PC:Chol:DOPE-N-DBCO(69:30:1molar ratio)-Neutral Fluoroliposome Rhodamine lipid (headgroup)-DBCO for live-cell tracking, targeted delivery, or bioconjugation experiments.It contains a bio-orthogonal DBCO handle for click chemistry. price>
R-XASYS-00263 MitoTEMPO (hydrate),cas:1569257-94-8 MitoTEMPO(C29H35N2O2P•Cl [H2O],528.0) is a mitochondria-targeted superoxide dismutase mimetic that possesses superoxide and alkyl radical scavenging properties.This compound combines the antioxidant piperidine nitroxide TEMPO with the lipophilic cation triphenylphosphonium. price>