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R-R-0283 FAPI-46 FAPI-46/CAS .2374782-04-2 is a quinoline-based fibroblast activation protein (FAP)-targeted radiotracer. FAPI-46 has higher tumor uptake and prolonged tumor accumulation. FAPI-46 can be used for tumor imaging of a multitude of different cancers. price>
R-Mcs-283 PH responsive PLGA nanoparticles loaded with a-Asarns and CY5.5 surface modified RVG29 PLGA nanoparticles loaded with a-Asarns and CY5.5 surface modified RVG29 is a targeted, brain-penetrating nanocarrier system built from PLGA nanoparticles, designed for drug delivery, neuroprotection, and bioimaging.It combines the therapeutic activity of α-Asarone,imaging capability of Cy5.5, and brain-targeting functionality of RVG29 peptide. Applications: Neurodegenerative disease therapy (e.g., Alzheimer, Parkinson). Anti-seizure or neuroinflammatory treatment. Brain-targeted drug delivery. Real-time imaging of biodistribution and CNS uptake. Theranostic nanomedicine (therapy + diagnostics). price>
R-XASYS-00284 Isorhynchophylline,cas:6859-01-4 Isorhynchophylline(C22H28N2O4,384.5) is an oxindole alkaloid that has been found in Uncaria and has diverse biological activities, including neuroprotective, anticancer, and antihypertensive properties. price>
R-R-0284 FAPI-4 FAPI-4/CAS.2374782-02-0 is a quinoline-based theranostic ligands for the targeting of Fibroblast Activation Protein. FAPI-4 was identified as the most promising tracer for clinical application. Compared with the previously published ligand, FAPI-4 showed excellent stability in human serum, higher affinity for FAP as opposed to CD26, and slower excretion in vitro. FAPI-4 represents a promising tracer for both diagnostic imaging and, possibly, targeted therapy of malignant tumors with a high content of activated fibroblasts, such as breast cancer. price>
R-Mcs-284 DOPG (Na⁺salt):DOPC:Chol-based Fluoroliposome Containing Encapsulated Fluorescent Dextran10K DOPG (Na⁺salt):DOPC:Chol(20:50:30:molar ratio)-based Fluoroliposome Containing Encapsulated Fluorescent Dextran10K describes a negatively charged, biocompatible liposome designed for tracking, encapsulation, and release of a high-molecular-weight fluorescent probe. Applications: Drug delivery research (as a carrier or control system). Fluorescence-based leakage or release studies. Cell uptake and endocytosis studies. Model system for encapsulating hydrophilic macromolecules. Bio-distribution studies in animal models. price>
R-XASYS-00285 IT-901,cas:1584121-99-2 IT-901 is an inhibitor of the NF-κB subunit c-Rel.It inhibits NF-κB DNA binding in HBL1 cells (IC50 = 0.1 µM) and reduces TNF-α-induced NF-κB activity in a reporter assay (IC50 = 4 µM). price>
R-R-0285 NOTA-FAPI NOTA-FAPI/CAS:2374782-03-1 is a fibroblast activation protein (FAP) inhibitor. NOTA-FAPI can be used as a probe for FAP-targeted tumour imaging. NOTA-FAPI has good tumour detection efficacy and excellent imaging quality. price>
R-Mcs-285 DOPG (Na⁺salt):DOPC:Chol-based Fluoroliposome Containing Encapsulated Texas Red-Dextran10K DOPG (Na⁺salt):DOPC:Chol(20:50:30:molar ratio)-based Fluoroliposome Containing Encapsulated Texas Red-Dextran10K describes a negatively charged, biocompatible fluorescent liposome system engineered for biological imaging, tracking, and release studies. Applications: Live-cell or tissue imaging. Liposome integrity and leakage studies. Macromolecular tracer release assays. Endocytosis or biodistribution tracking. Model system for drug delivery research. price>
R-XASYS-00286 JX06,cas:729-46-4 JX06(C10H16N2O2S4,324.5) is an irreversible inhibitor of pyruvate dehydrogenase kinases (PDHKs; IC50s = 49, 101, and 313 nM for PDHK1, PDHK2, and PDHK3, respectively).It is selective for PDHK1-3 over PDHK4 (IC50 = >10 µM) and 322 other kinases at 10 µM but does inhibit FAK in a cell-free panel but not in a cell-based assay. price>
R-R-0286 PSMA-1007 PSMA-1007 is a novel Glu-Ureido-type prostate-specific membrane antigen (PSMA) inhibitor. [18F]PSMA-1007 is a prostate specific membrane antigen (PSMA) ligand for positron emission tomography (PET) imaging of prostate cancer. price>
R-Mcs-286 DOPG (Na⁺salt):DOPC:Chol-based Fluoroliposome Containing Encapsulated Rhodamine B-Dextran10k DOPG (Na⁺salt):DOPC:Chol(20:50:30:molar ratio)-based Fluoroliposome Containing Encapsulated Rhodamine B-Dextran10k is a negatively charged, fluorescent liposome system designed for bioimaging, tracking, and controlled release studies, with Rhodamine B–labeled dextran (10 kDa) encapsulated in the aqueous core. It uses a well-balanced lipid composition to ensure stability, fluidity, and biocompatibility. price>
R-XASYS-00287 Isosilybin,cas:72581-71-6 Isosilybin(C25H22O10,482.4) is a flavanolignan found in the extract of S. marianum fruits with antioxidant and anticancer activities.It inhibits lipid peroxidation in rat liver microsomes (IC50 = 32 μM) and reduces ADP/Fe3+-induced malondialdehyde (MDA) production and lactate dehydrogenase (LDH) release in rat hepatocytes. price>
R-R-0287 PSMA11 PSMA-11/HBED-CC-PSMA/CAS .1366302-52-4 is a positron emission tomography (PET) tracer. PSMA-11 detects prostate cancer relapses and metastases by binding to the extracellular domain of prostate-specific membrane antigen (PSMA). price>
R-Mcs-287 DOPG (Na⁺salt):DOPC:Chol-based Fluoroliposome Containing Encapsulated Tetramethylrhodamine-Dextran DOPG (Na⁺salt):DOPC:Chol(20:50:30:molar ratio)-based Fluoroliposome Containing Encapsulated Tetramethylrhodamine-Dextran10k is a negatively charged, biocompatible fluorescent liposome system, engineered for cellular imaging, release studies, and tracking liposome integrity. It encapsulates tetramethylrhodamine-labeled dextran (TMR-Dextran 10K) in the aqueous core, providing a reliable fluorescent signal without interfering with membrane dynamics. price>
R-XASYS-00288 Ginsenoside Rb3,cas:68406-26-8 Ginsenoside Rb3(C53H90O22,1079.3) is a steroid glycoside that has been found in Panax and has diverse biological activities.It inhibits JNK-mediated activation of NF-κB and apoptosis induced by oxygen-glucose deprivation (OGD) in H9c2 mouse cardiac myoblasts in vitro and reduces myocardial apoptosis price>
R-R-0288 FAP inhibitors FAP inhibitors, also known as fibroblast activation protein inhibitors, are a type of medication that block the activity of the FAP enzyme.By inhibiting FAP activity, these inhibitors can potentially slow down tumor growth and metastasis, as well as enhance the response to chemotherapy and immunotherapy. They may also have anti-inflammatory effects and modulate the tumor microenvironment. price>
R-Mcs-288 DOPG (Na⁺salt):DOPC:Chol-based Fluoroliposome Containing Encapsulated pHrodo Red-Dextran10k DOPG (Na⁺salt):DOPC:Chol(20:50:30:molar ratio)-based Fluoroliposome Containing Encapsulated pHrodo Red-Dextran10k is a negatively charged, pH-sensitive fluorescent liposome designed for intracellular trafficking, endocytosis studies, and acidic environment detection. It encapsulates pHrodo™ Red, a pH-activatable dye, within the aqueous core of the liposome for environment-responsive fluorescence tracking. price>
R-XASYS-00289 Theaflavin,cas:4670-05-7 Theaflavin(C29H24O12,564.5) is a polyphenolic flavonoid that has been found in black tea and has diverse biological activities, including antioxidant, anticancer, anti-inflammatory, and antiviral properties.It scavenges singlet oxygen and hydrogen peroxide as well as superoxide and hydroxide radicals in vitro (IC50s = 0.73, 0.49, 14.5, and 38.0 µM. price>
R-R-0289 NH2-FAPI-4 NH2-FAPI-4 is a specific type of fibroblast activation protein inhibitor (FAPI).NH2-FAPI-4 is one of the FAPI derivatives designed to have higher stability and more favorable pharmacokinetic properties compared to earlier FAPI compounds. It has shown promising results in preclinical studies, demonstrating its ability to selectively accumulate in FAP-positive tumors and effectively inhibit FAP activity. price>
R-Mcs-289 DOPG (Na⁺salt):DOPC:Chol-based Fluoroliposome Containing Encapsulated pHrodo Green-Dextran10k DOPG (Na⁺salt):DOPC:Chol(20:50:30:molar ratio)-based Fluoroliposome Containing Encapsulated pHrodo Green-Dextran10k is a negatively charged, pH-sensitive fluorescent liposome specifically engineered for acidic environment detection, such as endosomes, lysosomes, or tumor tissues. It encapsulates pHrodo Green, a dye that fluoresces only in acidic pH, within the aqueous core of a lipid bilayer composed of DOPG, DOPC, and cholesterol. price>