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R-Mcs-296 DOPC:Cholesterol(70:30:molar ratio)-Containing Encapsulated Fluorescent Dextran10K DOPC:Cholesterol(70:30:molar ratio)-Containing Encapsulated Fluorescent Dextran10K is a neutral, biocompatible fluorescent liposome designed for tracer release studies, cellular uptake analysis, and nanocarrier research. Applications In vitro release studies in different pH or buffer conditions. Cellular uptake analysis using microscopy or flow cytometry. Endosomal trafficking tracking. Leakage testing under stress conditions (e.g., temperature, serum exposure). Model nanocarrier for hydrophilic payloads. price>
R-XASYS-00297 A23187,cas:52665-69-7 A23187 is a calcium ionophore and a microbial metabolite that has been found in S. chartreusensis.It induces calcium overload and mitochondrial apoptosis in HEK293 cells when used at a concentration of 5 µM. price>
R-R-0297 FAPI-12 FAPI-12/Fibroblast-activation-protein inhibitor-12 is a small molecule compound designed to target fibroblast activation protein (FAP), an enzyme that is overexpressed in the tumor microenvironment of various cancers, including pancreatic, colorectal, lung, and breast cancer. price>
R-Mcs-297 DOPC:Cholesterol(70:30:molar ratio)-Containing Encapsulated Texas Red-Dextran10K DOPC:Cholesterol(70:30:molar ratio)-Containing Encapsulated Texas Red-Dextran10K is a neutral, biocompatible fluorescent liposome, designed for cell tracking, membrane integrity testing, and controlled release studies. Applications Tracking cellular uptake via fluorescence microscopy or flow cytometry. Studying membrane integrity and release kinetics in various conditions. Leakage profiling during stress (e.g., pH, enzymes, serum exposure). Model for encapsulation of large hydrophilic drugs. Biodistribution studies in vitro or in vivo using red fluorescence. price>
R-XASYS-00298 Decylubiquinone,cas:55486-00-5 Decylubiquinone(C19H30O4,322.4) is an analog of ubiquinone (coenzyme Q10). It blocks reactive oxygen species production in response to glutathione depletion and inhibits activation of the mitochondrial permeability transition. price>
R-R-0298 FAPI-14 FAPI-14/Fibroblast-activation-protein inhibitor-14 is a small molecule compound designed to target fibroblast activation protein (FAP), an enzyme that is overexpressed in the tumor microenvironment of various cancers, including pancreatic, colorectal, lung, and breast cancer. price>
R-Mcs-298 DOPC:Cholesterol(70:30:molar ratio)-Containing Encapsulated Rhodamine B-Dextran10K DOPC:Cholesterol(70:30:molar ratio)-Containing Encapsulated Rhodamine B-Dextran10K is a neutral, biocompatible fluorescent liposome used for drug delivery research, fluorescent tracking, and liposomal stability assays. Applications Liposome uptake studies in live cells using fluorescence microscopy. Leakage/release profiling under stress, pH shifts, or enzyme exposure. Quantitative tracking via plate readers, spectrofluorimetry, or flow cytometry. In vitro/in vivo biodistribution models. Evaluation of bilayer integrity in drug delivery formulations. price>
R-XASYS-00299 Petunidin 3-O-glucoside,cas:6988-81-4 Petunidin 3-O-glucoside(C22H23O12•Cl,514.9) is an anthocyanin that has been found in red grapes and red wines with antiproliferative properties. price>
R-R-0299 FAPI-15 FAPI-15/Fibroblast-activation-protein inhibitor-15 is a small molecule compound designed to target fibroblast activation protein (FAP), an enzyme that is overexpressed in the tumor microenvironment of various cancers, including pancreatic, colorectal, lung, and breast cancer. price>
R-Mcs-299 DOPC:Cholesterol(70:30:molar ratio)-Containing Encapsulated Tetramethylrhodamine-Dextran10k DOPC:Cholesterol(70:30:molar ratio)-Containing Encapsulated Tetramethylrhodamine-Dextran10k is a neutral, biocompatible fluorescent liposome system designed for nanoparticle tracking, endocytic uptake studies, and release profiling. Applications Fluorescent tracking of liposome uptake in cells (via microscopy or flow cytometry). Leakage/release assays in response to pH, enzymes, or surfactants. Endosomal trafficking studies with stable fluorescence readout. Model system for encapsulating hydrophilic drugs or macromolecules. Integrity testing for long-term liposome storage or serum stability. price>
R-XASYS-00300 Se-Aspirin,cas:1850293-95-6 Se-Aspirin(C12H12N2O3Se,311.2) is a hybrid of selenium and a nonsteroidal anti-inflammatory drug that has been shown to reduce the viability of different cancer cell lines, particularly colorectal cancer (CRC) cells (IC50 = 3.4 µM). price>
R-R-0300 FAPI-2 FAPI-2/Fibroblast-activation-protein inhibitor-2/CAS .2370952-98-8 is a small molecule compound designed to target fibroblast activation protein (FAP), an enzyme that is overexpressed in the tumor microenvironment of various cancers, including pancreatic, colorectal, lung, and breast cancer. price>
R-Mcs-300 DOPC:Cholesterol(70:30:molar ratio)-Containing Encapsulated pHrodo Red-Dextran10k DOPC:Cholesterol(70:30:molar ratio)-Containing Encapsulated pHrodo Red-Dextran10k describes a neutral, pH-responsive fluorescent liposome designed for intracellular trafficking studies, endocytosis monitoring, and environmentally triggered fluorescence activation. price>
R-XASYS-00301 GLX-351322,cas:835598-94-2 GLX-351322(C21H25N3O5S,431.5) is an inhibitor of NADPH oxidase 4 (NOX4; IC50 = 5 µM).It is selective for NOX4 over NOX2 (IC50 = 40 µM). GLX-351322 (10 µM) reduces glucose-induced production of reactive oxygen species (ROS) and cytotoxicity in isolated human pancreatic islets. price>
R-R-0301 Fmoc-FAPI-4 Fmoc-FAPI-4 is a specific fibroblast activation protein inhibitor (FAPI) compound that is a member of the FAPI family of molecules. Fmoc-FAPI-4, like other FAPI compounds, is intended to selectively accumulate in FAP-positive tumors and disrupt the functions of cancer-associated fibroblasts (CAFs) in the tumor microenvironment. By inhibiting FAP activity, these compounds aim to potentially slow down tumor growth, enhance the efficacy of other cancer treatments, and modulate the tumor microenvironment. price>
R-Mcs-301 DOPC:Cholesterol(70:30:molar ratio)-Containing Encapsulated pHrodo Green-Dextran10k DOPC:Cholesterol(70:30:molar ratio)-Containing Encapsulated pHrodo Green-Dextran10k is a neutral, pH-sensitive fluorescent liposome system, ideal for endocytosis tracking, lysosomal trafficking, and pH-triggered delivery assessment. price>
R-XASYS-00302 Talaporfin (sodium salt),cas:220201-34-3 Talaporfin(C38H37N5O9•4Na,799.7) is a photosensitizer.It induces apoptosis, DNA double-strand breaks (DSBs), and the production of reactive oxygen species (ROS) in TE-11R 5-fluorouracil-resistant esophageal squamous cell carcinoma (ESCC) cells when used at a concentration of 30 µg/ml in combination with radiation. price>
R-R-0302 SH-FAPI-4 SH-FAPI-4 is a specific fibroblast activation protein inhibitor (FAPI) compound that belongs to the FAPI family of molecules. SH-FAPI-4 is expected to selectively accumulate in FAP-positive tumors and disrupt the functions of cancer-associated fibroblasts (CAFs) within the tumor microenvironment. By inhibiting FAP activity, this compound aims to potentially slow tumor growth, enhance the efficacy of other cancer treatments, and modulate the tumor microenvironment. price>
R-Mcs-302 DOTAP:DOPC:Chol-based Fluoroliposome Containing Encapsulated Fluorescent Dextran10K DOTAP:DOPC:Chol(5:65:30:molar ratio)-based Fluoroliposome Containing Encapsulated Fluorescent Dextran10K is a mildly cationic, biocompatible fluorescent liposome system, engineered for bioimaging, endocytosis studies, and controlled-release tracking. price>
R-XASYS-00303 CAY10730,cas:2206677-06-5 CAY10730 is a turn-on fluorescent probe for the detection of nitroreductase activity, a marker of hypoxia.In the presence of nitroreductase, CAY10730 is transformed into a highly fluorescent molecule that displays excitation/emission maxima of 454/520 nm, respectively. price>