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R-R-0303 FAPI FAPI stands for fibroblast activation protein inhibitor. FAPI compounds are a class of small molecule inhibitors designed to target and inhibit fibroblast activation protein (FAP). FAP is an enzyme that is overexpressed in the tumor microenvironment of various cancers, including pancreatic, colorectal, lung, and breast cancer. price>
R-Mcs-303 DOTAP:DOPC:Chol(5:65:30:molar ratio)-based Fluoroliposome Containing Encapsulated Texas Red-Dextran DOTAP:DOPC:Chol(5:65:30:molar ratio)-based Fluoroliposome Containing Encapsulated Texas Red-Dextran10k describes a mildly cationic,fluorescent liposome designed for cell uptake studies, membrane integrity analysis, and fluorescence-guided tracking. price>
R-XASYS-00304 Fuziline,cas:80665-72-1 Fuziline is a diterpene alkaloid that has been found in A. lateralis and has cardioprotective activity.It reduces sodium pentobarbital-induced cell death in primary neonatal rat cardiomyocytes when used at concentrations ranging from 0.1 to 10 µM. price>
R-R-0304 UAMC1110 UAMC-1110, also known as SP-13786, is a novel potent and selective inhibitor of fibroblast activation protein (fap), displaying low nanomolar inhibitory potency and high selectivity against the related dipeptidyl peptidases (dpps) dppiv, dpp9, dppii, and prolyl oligopeptidase (prep). price>
R-Mcs-304 DOTAP:DOPC:Chol-based Fluoroliposome Containing Encapsulated Rhodamine B-Dextran10k DOTAP:DOPC:Chol(5:65:30:molar ratio)-based Fluoroliposome Containing Encapsulated Rhodamine B-Dextran10k is a mildly cationic, biocompatible fluorescent liposome specifically formulated for tracking, cellular uptake, and membrane integrity studies. price>
R-XASYS-00305 Necrox-5 (methanesulfonate),cas:1383718-29-3 Necrox-5(C25H31N3O3S•2CH4O3S,1383718-29-3) is a cell permeable inhibitor of necrosis that also demonstrates strong mitochondrial reactive oxygen species and ONOO- scavenging activity.It predominantly localizes in mitochondria, selectively blocking oxidative stress-induced necrotic cell death (0.1 μM necrox-5 inhibits ~50% cell death in H9C2 cells exposed to 400 μM t-BHP) price>
R-R-0305 NH2-UAMC1110 NH2-UAMC1110 is a UAMC1110 derivative that can be used in the synthesis of FAPI-QS. FAPI-QS is a chelating agent that can be used to manufacture high tumor selectivity and high dose radiotracers for the diagnosis and treatment of tumors. price>
R-Mcs-305 DOTAP:DOPC:Chol-based Fluoroliposome Containing Encapsulated Tetramethylrhodamine-Dextran10k DOTAP:DOPC:Chol(5:65:30:molar ratio)-based Fluoroliposome Containing Encapsulated Tetramethylrhodamine-Dextran10k is a mildly cationic, fluorescent liposome designed for live-cell tracking, endocytosis research, and release profiling. price>
R-XASYS-00306 Terrecyclic Acid,cas:83058-94-0 Terrecyclic acid is a sesquiterpene originally isolated from A. terreus with antibiotic and anticancer activity.It is active against S. aureus, B. subtilis, and M. roseus (MICs = 25, 50, and 25 μg/ml, respectively). Terrecyclic acid induces a heat shock response, increases levels of reactive oxygen species (ROS), and inhibits NF-κB activity and cell growth in 3T3-Y9-B12 cells. price>
R-R-0306 DOTA-Octreotide DOTA-Octreotide, also known as DOTA-TOC, is a radiolabeled peptide-based radiopharmaceutical used in diagnostic imaging and targeted therapy for certain neuroendocrine tumors (NETs). price>
R-Mcs-306 DOTAP:DOPC:Chol(5:65:30:molar ratio)-based Fluoroliposome Containing Encapsulated pHrodo Red-Dextran DOTAP:DOPC:Chol(5:65:30:molar ratio)-based Fluoroliposome Containing Encapsulated pHrodo Red-Dextran10k is a mildly cationic, pH-sensitive fluorescent liposome engineered for cell uptake tracking, acidic organelle targeting, and pH-triggered delivery studies. price>
R-XASYS-00307 Daunorubicin (hydrochloride),cas:23541-50-6 Daunorubicin is an antitumor antibiotic.1 At 0.2-1μM, daunorubicin induces apoptosis in mature monocytic U937 and myelocytic HL-60 acute myeloid leukemia (AML) cells. However, immature AML cells (CD 34+-KG1a, -KG1, or -HEL cells) appear resistant to apoptosis at similar concentrations. price>
R-R-0307 Hynic-TOC Hynic-TOC/Hynic-Toc Trifluoroacetate/Cas257943-19-4 from ruixi. Hynic-TOC, also known as 6-hydrazinonicotinyl-Tyr3-octreotide, is a radiolabeled peptide-based radiopharmaceutical used in nuclear medicine imaging. price>
R-Mcs-307 DOTAP:DOPC:Chol-based Fluoroliposome Containing Encapsulated pHrodo Green-Dextran10k DOTAP:DOPC:Chol(5:65:30:molar ratio)-based Fluoroliposome Containing Encapsulated pHrodo Green-Dextran10k is a mildly cationic, pH-sensitive fluorescent liposome, optimized for cellular uptake studies, acidic compartment tracking, and pH-responsive delivery analysis. Applications Live-cell imaging of liposome internalization and endosomal trafficking. Quantifying pH-sensitive uptake and delivery. Assessing pH-triggered release or fusion of liposomes in biological media. Nanoparticle design validation for acid-sensitive delivery platforms. Fluorescence-based assays using microscopy, flow cytometry, or plate readers. price>
R-XASYS-00308 Procyanidin B1,cas:20315-25-7 Procyanidin B1(C30H26O12,578.5) is a polyphenol flavonoid existing as a dimer of (+)-catechin and (−)-epicatechin. It inhibits hepatitis C virus RNA replication (EC50 = 72 µM), while (+)-catechin and (−)-epicatechin do not, up to concentrations of 200 µM.1 Procyanidin B1 (10 µg/ml) price>
R-R-0308 Pentixafor CAS: 1341207-62-2 Pentixafor is a medicinal compound that has been developed as an anticancer agent. This compound is an analog of the CXCR4 receptor inhibitor, which is found in human urine and Chinese medicinal herbs. Pentixafor works by inhibiting kinases that are involved in cancer cell growth and survival, leading to apoptosis or programmed cell death. It specifically targets tumor cells and prevents them from spreading to other parts of the body. Pentixafor has shown promising results in preclinical studies for the treatment of various types of cancer, including breast, prostate, and lung cancer. Its ability to selectively target cancer cells makes it a potential breakthrough in cancer treatment research. price>
R-Mcs-308 L-α-PC:Chol:DOPE-Glutaryl(69:30:1molar ratio) Fluorescent Lipid DiI L-α-PC:Chol:DOPE-Glutaryl(69:30:1molar ratio) Fluorescent Lipid DiI is a fluorescently traceable, surface-modifiable liposome. Applications: Live-cell imaging of liposome uptake and trafficking. Targeted delivery platform (via DOPE–Glutaryl–ligand conjugation). Membrane interaction or fusion assays using DiI fluorescence. In vivo biodistribution studies of fluorescent nanoparticles. Functionalization with antibodies or peptides via EDC/NHS chemistry. price>
R-XASYS-00309 Sitamaquine (tosylate),cas:1019640-33-5 Sitamaquine(C21H33N3O•C7H8O3S,515.7) is an antileishmanial agent.It is active against L. donovani, L. infantum, L. mexicana, L. braziliensis, and L. tropica.It inhibits mitochondrial complex II, also known as succinate dehydrogenase (SDH), in a cell-free assay when used at concentrations ranging from 10 to 200 µM. price>
R-R-0309 NOTA-NFB NOTA-NFB is a very useful peptide labeling reagent that can label proteins or other biomolecules with groups with specific functions. By using NOTA-NFB, it is easier to study the function and behavior of biomolecules, as well as their interactions with other molecules. price>
R-Mcs-309 L-α-PC:Chol:DOPE-Glutaryl(69:30:1molar ratio) Fluorescent Lipid DiO L-α-PC:Chol:DOPE-Glutaryl(69:30:1molar ratio) Fluorescent Lipid DiO is designed for surface functionalization and green fluorescence-based tracking. Applications: Fluorescent tracking of liposomes in vitro and in vivo. Live-cell uptake studies using green fluorescence. Conjugation to targeting ligands for cell- or tissue-specific delivery (via DOPE–Glutaryl). Dual-labeling with other fluorophores for multicolor analysis. Membrane fusion or interaction assays. price>