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R-Mcs-316 L-α-PC:Chol:DOPE-Glutaryl(69:30:1molar ratio) Fluorescent Lipid Dansyl lipid (headgroup) L-α-PC:Chol:DOPE-Glutaryl(69:30:1molar ratio) Fluorescent Lipid Dansyl lipid (headgroup) is a neutral fluorescent liposome. A dansyl-labeled lipid is incorporated at the headgroup level to enable fluorescent visualization or analytical tracking. price>
R-XASYS-00317 Kaempferol 3-glucuronide,cas:22688-78-4 Kaempferol 3-glucuronide(C21H18O12,462.4) is a flavonol glycoside that has been found in Fragaria and an active metabolite of kaempferol that has diverse biological activities.It is formed from kaempferol primarily in the small intestine. price>
R-R-0317 (68Ga)Nota-prgd2 (68Ga)NOTA-PRGD2/CAS:1345968-02-6 is a radiolabeled compound used in molecular imaging and targeted therapy for cancer.In addition to its imaging applications, (68Ga)NOTA-PRGD2 can also be explored for targeted therapy. For example, therapeutic agents or radioisotopes can be attached to the peptide sequence, potentially allowing for the specific delivery of treatment to cancer cells expressing high levels of integrin receptors. price>
R-Mcs-317 L-α-PC:Chol:DOPE-Glutaryl(69:30:1molar ratio) Fluorescent Lipid Pyrene lipid (headgroup) L-α-PC:Chol:DOPE-Glutaryl(69:30:1molar ratio) Fluorescent Lipid Pyrene lipid (headgroup) is a neutral fluorescent liposome. A pyrene-labeled lipid, with the fluorophore attached to the headgroup, is incorporated for fluorescent tracking or analysis. price>
R-XASYS-00318 Yatein,cas:40456-50-6 Yatein(C22H24O7,400.4) is a lignan that has been found in C. formosana and has diverse biological activities.It inhibits the cytochrome P450 (CYP) isoform CYP3A4 (IC50 = 1 μM).Yatein inhibits herpes simplex virus (HSV-1) replication in a plaque reduction assay (IC50 = 30.6 μM). price>
R-R-0318 NOTA-WL12 NOTA-WL12 is a chelator-peptide conjugate, which can be used in molecular imaging and targeted therapy.NOTA-WL12 can potentially be used in targeted therapy. By attaching therapeutic agents or radioisotopes to the WL12 peptide, it can be used to deliver treatment specifically to the cells or tissues expressing the target protein or receptor, potentially enhancing the efficacy of the treatment and reducing side effects. price>
R-Mcs-318 L-α-PC:Chol:DOPE-Succinyl(69:30:1molar ratio) Fluorescent Lipid DiA L-α-PC:Chol:DOPE-Succinyl(69:30:1molar ratio) Fluorescent Lipid DiA is a neutral fluorescent liposome,for potential chemical conjugation. A DiA-labeled lipid (DiA: 4-(4-(dihexadecylamino)styryl)-N-methylpyridinium iodide) is incorporated for membrane fluorescence labeling, with the dye embedded in the lipid bilayer due to its long alkyl chains. price>
R-XASYS-00319 Methylophiopogonanone B,cas:74805-91-7 Methylophiopogonanone B(C19H20O5,328.4) is an isoflavone that has been found in O. japonicus and has diverse biological activities.It increases Rho activity in normal human epidermal melanocytes (NHEMs) when used at a concentration of 1 µM. price>
R-R-0319 Dota-ggga Dota-ggga, also known as D-ggga CAS:149206-86-0, is a chemical compound that has recently gained attention in the scientific community due to its potential therapeutic applications. This compound has been found to have a unique mechanism of action that makes it a promising candidate for the treatment of various diseases. price>
R-Mcs-319 L-α-PC:Chol:DOPE-Succinyl(69:30:1molar ratio) Fluorescent Lipid DiD L-α-PC:Chol:DOPE-Succinyl (69:30:1) DiD-labeled liposomes were used to monitor cellular uptake in real time via live-cell fluorescence microscopy and in vivo biodistribution imaging. This liposome serves as a stable, trackable nanocarrier with: Long-wavelength fluorescence (DiD) for deep-tissue imaging; Mildly anionic surface due to succinylated DOPE; Suitability for further surface modification (via -COOH); High compatibility for cell tracking, biodistribution, and drug delivery studies. price>
R-XASYS-00320 Cardanol monoene,cas:501-26-8 Cardanol monoene(C21H34O,302.5) is a phenol found in cashew nut shell liquid that reversibly inhibits tyrosinase with an IC50 value of 56 µM in vitro.It halts the cell cycle at the S phase and inhibits proliferation dose- and time-dependently in M14 melanoma cells (IC50s = 23.15 and 12.30 µM after 24 and 48 hours of treatment, respectively). price>
R-R-0320 cyclic Arg(Pbf)-Gly-Asp(Ot-Bu)-D-Tyr(Ot-Bu)-Lys(NH2) Cyclic Arg(Pbf)-Gly-Asp(Ot-Bu)-D-Tyr(Ot-Bu)-Lys(NH2)/CAS: 903518-34-3 refers to a specific sequence of amino acids forming a cyclic peptide. Arg-Gly-Asp-Tyr-Lys in this peptide is of particular interest in the field of peptide chemistry and molecular biology, as it is a component of the RGD (Arg-Gly-Asp) motif, which has high affinity for integrin receptors and is involved in cell adhesion, migration, and other cellular processes. Peptides containing the RGD motif have been extensively studied for their potential applications in targeted drug delivery, molecular imaging, and as therapeutics for conditions such as cancer and angiogenesis-related diseases. price>
R-Mcs-320 L-α-PC:Chol:DOPE-Succinyl(69:30:1molar ratio) Fluorescent Lipid DiI L-α-PC:Chol:DOPE-Succinyl(69:30:1molar ratio) Fluorescent Lipid DiI is a neutral or mildly anionic fluorescent liposome. L-α-PC:Chol:DOPE-Succinyl (69:30:1) liposomes labeled with DiI were used to visualize membrane fusion events and assess intracellular trafficking via confocal fluorescence microscopy. price>
R-XASYS-00321 Lipofermata,cas:297180-15-5 Lipofermata(C15H10BrN3OS,360.2) is an inhibitor of fatty acid transport (IC50 = 4.84 μM in Caco-2 cells).It inhibits uptake of long- and very long-chain, but not medium-chain, fatty acids in mmC2C12, rnINS-1E, Caco-2, and HepG2 cells (IC50s = 3-6 μM).Lipofermata inhibits induction of BiP and CHOP, apoptosis, and lipid droplet accumulation. price>
R-R-0321 Cyclo(-RGDfK) Cyclo(-RGDfK)/cas:161552-03-0 is a cyclic peptide sequence containing the RGD motif. Cyclo(-RGDfK) and related cyclic peptides containing the RGD motif have been extensively studied for their potential applications in cancer targeting, tumor imaging, and angiogenesis inhibition. These peptides have shown promise in targeted drug delivery systems, molecular imaging, and as therapeutic agents due to their high affinity for integrin receptors, which are often overexpressed in cancer cells and angiogenic blood vessels. price>
R-Mcs-321 L-α-PC:Chol:DOPE-Succinyl(69:30:1molar ratio) Fluorescent Lipid DiO L-α-PC:Chol:DOPE-Succinyl(69:30:1molar ratio) Fluorescent Lipid DiO were used to monitor cellular uptake in real time via live-cell fluorescence microscopy and in vivo biodistribution imaging. price>
R-Mcs-322 L-α-PC:Chol:DOPE-Succinyl(69:30:1molar ratio) Fluorescent Lipid DiR L-α-PC:Chol:DOPE-Succinyl(69:30:1molar ratio) Fluorescent Lipid DiR were used to monitor cellular uptake in real time via live-cell fluorescence microscopy and in vivo biodistribution imaging. price>
R-XASYS-00322 Sesamolin,cas:526-07-8 Sesamolin(C20H18O7,370.4) is a lignin found in S. indicum with diverse biological activities. It reduces lipid peroxidation in rat liver and kidneys in vivo but has no effect on lipid peroxidation activity of rat liver microsomes in vitro. price>
R-R-0322 Cyclic(RGDyK) Cyclo(RGDyK)/CAS: 250612-42-1 is a selective and potent αVβ3 integrin inhibitor with IC50 value of 20 nM [1]. The αVβ3 integrin, expressed on various malignant human tumors and on endothelial cells, plays an important role in tumor-induced angiogenesis and tumor metastasis. Therefore, αVβ3 integrin is a potential therapeutic target for tumor disease. Inhibition of αVβ3 integrin by αVβ3 antagonists not only blocked blood vessel formation but further led to tumor regression. price>
R-XASYS-00323 Cinnabarinic Acid,cas:606-59-7 Cinnabarinic acid(C14H8N2O6,300.3) is an agonist of metabotropic glutamate receptor 4 (mGluR4) and active metabolite of 3-hydroxyanthranilic acid.It is formed via two-step oxidation of 3-hydroxyanthranilic acid. price>