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R-R-1112 Sophocarpine monohydrate CAS No.145572-44-7 Sophocarpine (monohydrate)/CAS No.145572-44-7 is one of the significant alkaloid extracted from the traditional herb medicine Sophora flavescens which has many pharmacological properties such as anti-virus, anti-tumor, anti-inflammatory. Sophocarpine (monohydrate) significantly inhibits the growth of gastric cancer (GC) cells through multiple mechanisms such as induction of autophagy, activation of cell apoptosis and down-regulation of cell survival PI3K/AKT signaling pathway. Sophocarpine (monohydrate) has been demonstrated to have anti-tumor activity in various cancer cells, including hepatocellular carcinoma, prostate cancer and colorectal cancer. price>
R-POL1398-X PAA-SH Poly(acrylic acid), (α-thiol, ω-bromo)-terminated PAA-SH SH-PAA from ruixi Amphiphilic block copolymer PAA-SH.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-DP-064 DSPE-PEG-PEI PEG-PEI is a copolymer of cationic poly (ethylene imine) (PEI) and polyethylene glycol (PEG).It has been well studied and can significantly improve the delivery of oligonucleotides and nucleic acids (DNA, siRNA) in vitro and in vivo.By changing the MW of Pei and PEG,PEG-PEI drug conjugates,polymers or nanoparticles with dynamic range,surface charge and stability can be prepared,which is important for transfection efficiency. price>
R-R-1113 Phellodendrine CAS No.6873-13-8 Phellodendrine/CAS No.6873-13-8, a isoquinoline alkaloid, is one of important characteristic ingredients in the Phellodendron amurense. phellodendrine is against AAPH-induced oxidative stress through regulating the AKT/NF-κB pathway. Phellodendrine has good antioxidant, and anti-inflammatory effect . price>
R-PL-0078 PMAA-NH2 Poly(methacrylic acd), α-amino-terminated PMAA-NH2 NH2-PMAA from ruixi Amphiphilic block copolymer PMAA-NH2.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-DP-132 DSPE-PEG-Chitin Chitin,also known as chitin,is the structure of N-acetylglucosamine which is polymerized by β- linkage.Polyethylene glycol is a polymer of ethylene oxide hydrolysate,which is non-toxic and non irritating,and is widely used in various pharmaceutical preparations. price>
R-R-1114 Alphitolic acid CAS No.19533-92-7 Alphitolic acid (Aophitolic acid)/CAS No.19533-92-7 is an anti-inflammatory triterpene could found in quercus aliena. Alphitolic acid blocks Akt–NF-κB signaling to induce apoptosis. Alphitolic acid induces autophagy. Alphitolic acid has anti-inflammatory activity and down-regulates the NO and TNF-α production. Alphitolic acid can be used for cancer and inflammation research. price>
R-PL-0079 PtBA-NH2 Poly(tert-butyl acrylate), α-amino-terminated PtBA-NH2 NH2-PtBA Amphiphilic block copolymer PtBA-NH2.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-DP-095 DSPE-PEG2K-MMPs MMPs can degrade almost all kinds of protein components in the extracellular matrix (ECM),destroy the histological barrier of tumor cell invasion,and play a key role in tumor invasion and metastasis.According to the substrate and fragment homology,MMPs can be divided into six categories:collagenase, gelatinase,matrix degradation factor,matrix lysin,furin activated MMP and other secreted MMP. price>
R-R-1115 MKC-1 CAS No.125313-92-0 MKC-1 (Ro-31-7453)/CAS No.125313-92-0 is an orally active and potent cell cycle inhibitor with broad antitumor activity. MKC-1 inhibits the Akt/mTOR pathway. MKC-1 arrests cellular mitosis and induces cell apoptosis by binding to a number of different cellular proteins including tubulin and members of the importin β family. price>
R-PL-0080 COOH-PtBA-COOH Poly(tert-butyl acrylate), α,ω-bis(carboxy)-terminated COOH-PtBA-COOH COOH-PtBA-COOH from ruixi Triblock copolymer COOH-PtBA-COOH .The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-DP-097 DSPE-PEG-GRGDS Glycine arginine glycine aspartic acid serine(grgds)is a pentapeptide containing RGD sequence.It plays an important role in monitoring angiogenesis around tumor tissue and can be used in the design of targeted delivery system of anticancer drugs.Grgds modified liposomes can be used as a carrier of anticancer drugs to target tumor cells,which provides a new idea for tumor targeted therapy. price>
R-R-1116 Arnicolide D CAS No.34532-68-8 Arnicolide D/CAS No.34532-68-8 is a sesquiterpene lactone isolated from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling pathways. Arnicolide D inhibits Nasopharyngeal carcinoma (NPC) cell viability in a concentration- and time-dependent manner. price>
R-PL-0081 PtBA-SH Poly(tert-butyl acrylate), (α-thiol, ω-bromo)-terminated PtBA-SH SH-PtBA from ruixi Amphiphilic block copolymer PtBA-SH.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-D-002-2k DSPE-PEG-DSPE Phospholipid peg is an excellent material for preparing liposomes.Modification of proteins,peptides and other small molecular materials.It is widely used in drug release,nano material research and cell culture. price>
R-R-1117 AKT-IN-3 CAS No.2374740-21-1 AKT-IN-3 (compound E22)/CAS No.2374740-21-1 is a potent, orally active low hERG blocking Akt inhibitor, with 1.4 nM, 1.2 nM and 1.7 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-3 (compound E22) also exhibits good inhibitory activity against other AGC family kinases, such as PKA, PKC, ROCK1, RSK1, P70S6K, and SGK. AKT-IN-3 (compound E22) induces apoptosis and inhibits metastasis of cancer cells. price>
R-PL-0082 PtBMA-NH2 Poly(tert-butyl methacrylate), α-amino-terminated PtBMA-NH2 NH2-PtBMA from ruixi Amphiphilic block copolymer PtBMA-NH2.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid price>
R-DP-096 DSPE-PEG-iRGD DSPE peg irgd is provided by Ruixi. Irgd peptide (cyclo (crgdkgpdc)) is a cyclic peptide composed of nine amino acids.It first binds to AV integrins,and then enzymolysis produces crgdk/R,which interacts with neuropilin-1,thus promoting the tissue penetration of drugs and targeting tumor and tumor infiltration. price>
R-R-1118 SY-LB-35 CAS No.2603461-70-5 SY-LB-35/CAS No.2603461-70-5 is a potent bone morphogenetic protein (BMP) receptor agonist. SY-LB-35 can stimulate significant increases in cell number and cell viability in the C2C12 myoblast cell line, and causes shifts towards the S and G2/M phases of the cell cycle. SY-LB-35 stimulates canonical Smad and non-canonical PI3K/Akt, ERK, p38 and JNK intracellular signaling pathways. price>
R-PL-0084 PMMA-NH2 Poly(methyl methacrylate), α-amino-terminated PMMA-NH2 NH2-PMMA from ruixi Amphiphilic block copolymer PMMA-NH2.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>