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R-SZ-0002 UCNPS-COOH Carboxylation is a large class of chemical reactions in organic chemistry,which refers to the addition of carboxyl functional groups to substrates,and the reverse reaction is decarboxylation.The long wavelength near-infrared light-emitting materials can be converted into visible light or ultraviolet light with shorter wavelength through photon up conversion process.Rare earth upconversion luminescent material is a kind of luminescent material which can emit visible light under near-infrared light excitation.It can convert long wave radiation into short wave radiation through multi-photon mechanism,so it is called up conversion.Its characteristic is that the photon energy absorbed by the material is lower than that emitted by the material. price>
R-DS-0042 DSPE-PEG-HBVpreS1(2-21Aa) Using HBVPreS1/2-21myr as target medium,long-acting circulating liposome (LCL) as drug carrier and fluorescein sodium (FS) as fluorescence mode to evaluate drugs,a novel drug delivery system targeting NTCP receptor was prepared by ethanol injection.HBVPreS1/2-21myr-peg2000-dspe was used as the raw material of liposome synthesis,mixed with soybean phospholipid,cholesterol and other liposome formula components,heated and prepared liposomes. price>
R-R-1135 Rotundic acid CAS No.20137-37-5 Rotundic acid/CAS No.20137-37-5, a triterpenoid obtained from Ilex rotunda Thunb., induces DNA damage and cell apoptosis in hepatocellular carcinoma through AKT/mTOR and MAPK Pathways. Rotundic acid possesses anti-inflammatory and cardio-protective abilities. price>
R-PL-0098 PCL-PEG-Silane poly(ε-caprolactone)-polyethylene glycol--silane.PCL-PEG-Silane from ruixi Triblock copolymer PCL-PEG-Silane.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-SZ-0001 UCNPS-NH2 upconversion fluorescent nanomaterials have the advantages of high fluorescence intensity,good stability and high detection sensitivity,and show broad application prospects in the fields of biology and medicine.Ruixi can provide such products Amino-functionalized upconverting nanoparticles. price>
R-DS-0043 DSPE-PEG2000-MAL-RGD(Arg-Gly-Asp-DPhe-Cys) A novel amphiphilic polymer block (dspe-peg2000-mal-RGD)was synthesized by linking RGD peptide with dspe-peg2000-mal.the BODIPY fluorescent dye was self-assembled with dspe-peg2000-mal-RGD to obtain a water-soluble bodipy-pc-RGD fluorescent probe complex,The optical properties of the fluorescent probe were measured by field emission transmission electron microscope and fluorescence microscope.It was found that the fluorescent probe had regular morphology, uniform size,about 143 nm in diameter,and had good near-infrared fluorescence characteristics. price>
R-R-1136 Cyclovirobuxine D CAS No.860-79-7 Cyclovirobuxine D (CVB-D)/CAS No.860-79-7 is the main active component of the traditional Chinese medicine Buxus microphylla. Cyclovirobuxine D induces autophagy and attenuates the phosphorylation of Akt and mTOR. Cyclovirobuxine D inhibits cell proliferation of gastric cancer cells through suppression of cell cycle progression and inducement of mitochondria-mediated apoptosis. Cyclovirobuxine D is beneficial for heart failure induced by myocardial infarction. price>
R-PL-0099 PCL-PEG-ACRL poly(ε-caprolactone)-polyethylene glycol--Acrylates,PCL-PEG-ACRL from ruixi poly(ε-caprolactone)-polyethylene glycol--Acrylates (PCL-PEG-ACRL) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery. price>
R-AS-0003 UCNPS-Biotin Biotin is the carrier of carboxyl group in many carboxylation reactions requiring ATP.The carboxyl group temporarily binds to a nitrogen atom in the biotin bicyclic system,such as in the pyruvate carboxylase catalyzed carboxylation of pyruvate to oxaloacetic acid.Animal lack of biotin causes skin diseases and hair loss.Upconversion nanoparticles have been widely used in biomedical field due to their excellent photostability,including in vitro bioimaging,in vivo bioimaging,biological detection,immunohistochemistry, microarray detection,photodynamic therapy and light controlled drug activation. price>
R-DS-0044 DSPE-PEG3400-c(RGDfk)(cyclo (Arg-Gly-Asp-d-Phe-Lys)) Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs. price>
R-R-1137 PF-AKT400 CAS No.1004990-28-6 PF-AKT400/CAS No.1004990-28-6 is a broadly selective, potent, ATP-competitive Akt inhibitor, displays 900-fold greater selectivity for PKBα (IC50=0.5 nM) than PKA (IC50=450 nM). price>
R-PLA-0038 3 arm/4 arm/6 arm/21 arm-PS Star Polymer 3 arm/4 arm/6 arm/21 arm-2-Polystyrene Star Polymer,3 arm/4 arm/6 arm/21 arm-PS Star Polymer from ruixi.3 arm/4 arm/6 arm/21 arm-PS is both star polymer and block polymer.Star polymers consist of many linear polymers fused at the central point and a large number of chain-end functions. Because of this unique structure, star polymers exhibit remarkable properties and properties that simple linear polymers cannot achieve. Therefore, they constitute a unique and technically important class of nanomaterials, which have been or are being used in many applications of life science and nanotechnology. price>
R-AS-0004 UCNPS-FA Upconversion luminescent nanomaterials (ucnps) have high chemical stability, excellent light stability,narrow band gap emission,strong tissue penetration ability under the excitation of near-infrared laser,no damage to biological tissue,no interference of background fluorescence,etc.it has a wide range of applications in biomedicine,such as biological imaging,biological detection, multimodal imaging,cancer photodynamic therapy,and so on Medicine,etc.Folic acid,found in plants,is a B-group vitamin and a water-soluble vitamin. price>
R-DS-1000 DSPE-PEG2000-CRGDK(Cys-Arg-Gly-Asp-Lys) Polyethylene glycol phospholipid is an excellent material to form liposomes, which can be used for gene transfection,vaccine delivery,drug delivery and targeted drug use.Phospholipids are hydrophobic and hydrophilic.It can be used to modify protein drugs,peptide compounds,organic small molecule drugs,biomaterials and so on.CRGDK is a straight chain. price>
R-R-1138 CHPG CAS No.170846-74-9 CHPG/CAS No.170846-74-9 is a selective mGluR5 agonist, and attenuates SO2-induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells. CHPG protects against traumatic brain injury (TBI) in vitro and in vivo by activation of the ERK and Akt signaling pathways. price>
R-PL-0100 PCL-PEG-LA poly(ε-caprolactone)-polyethylene glycol--Lipoic acid,PCL-PEG-LA from ruixi poly(ε-caprolactone)-polyethylene glycol--Lipoic acid (PCL-PEG-LA ) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery. price>
R-SZ-0003 UCNPS-PEG Compared with traditional fluorescent materials,upconversion fluorescent nanoparticles have the following advantages:1) near-infrared light as excitation light source,1) improve its penetration ability in biological tissues;2) reduce the damage of light source to biological samples;3) as the absorption of light in vivo is mainly concentrated in the ultraviolet visible region,so it is less interfered by autofluorescence.These advantages make upconversion fluorescent materials widely used in molecular detection and imaging in vivo. price>
R-DS-0045 DSPE-PEG3400-RGERPPR DSPE conjugated polyethylene glycol is a combination of phospholipid and polyethylene glycol,which has hydrophilicity and hydrophobicity.Polyethylene glycol phospholipid liposomes can be used for drug delivery,gene transfection and vaccine delivery.Pegylated phospholipids can significantly improve blood circulation time and stabilize drug encapsulation.These materials can also be used for targeted drug delivery by modifying ligands with target surfaces such as antibodies and peptides. price>
R-R-1139 AKT-IN-6 CAS No.1430056-54-4 AKT-IN-6 (Example 13)/CAS No.1430056-54-4 is a potent Akt inhibitor. AKT-IN-6 inhibits Akt1, Akt2 and Akt3 with IC50s < 500nM, respectively. (patent WO2013056015A1). price>
R-PL-0101 PCL-PEG-Tosyl poly(ε-caprolactone)-polyethylene glycol--Tosylate PCL-PEG-Tosyl from ruixi poly(ε-caprolactone)-polyethylene glycol--Tosylate (PCL-PEG-Tosyl ) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery. price>