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Catalog	name	Description	price
R-DS-0061	DSPE-PEG-TxID	Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs.Peptide carrier targeting technology is known as a new generation of targeted drug development technology.	price>
R-R-1155	KP372-1 CAS No.1374996-60-7	KP372-1/CAS No.1374996-60-7 is an Akt inhibitor that inhibits proliferation and induces apoptosis and anoikis. KP372-1 is also an NQO1 redox cycling agent that causes DNA damage (including DNA breakage) by generating ROS. KP372-1 can be used in cancer research (such as head and neck squamous cell carcinoma (HNSCC) and pancreatic cancer).	price>
R-PL-0117	4arm/8arm-PLA-PEG	4arm/8arm Poly(D,L-lactide)-polyethylene glycol,4arm/8arm-PLA-PEG from ruixi Multiarm block copolymers 4arm/8arm-PLA-PEG. .The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid.	price>
RY-C-0817	mPEG-SS-NH2	Polymer micelles are a kind of nanoparticles with unique core-shell structure formed by self-assembly of amphiphilic polymers in selective solvents.They are commonly used as self-contained drug carriers.	price>
R-DS-0062	DSPE-PEG-TR	The active and passive DSPE-PEG micelles containing coumarin-6 were constructed by linking tr peptide with DSPE-PEG.After that,we separated glioma stem cells by fluorescence activated immune cell sorting method and tumor ball culture method. By confocal microscopy and flow cytometry,the uptake of TR modified micelles by tumor stem cells was increased,which proved that tr modified micelles were targeted in vitro.	price>
R-R-1156	SEW2871 CAS No.256414-75-2	SEW2871/CAS No.256414-75-2 is an orally active, potent, highly selective S1P1 (sphingosine-1-phosphate type 1 receptor) agonist, with an EC50 of 13.8 nM. SEW2871 activates ERK, Akt, and Rac signaling pathways and induces S1P1 internalization and recycling. SEW2871 reduces lymphocyte numbers in blood.	price>
R-PL-0118	PLA-PEG-CHEMS	Poly(D,L-lactide)-polyethylene glycol-CHEMS, PLA-PEG-CHEMS from ruixi Poly(D,L-lactide)-polyethylene glycol-CHEMS (PLA-PEG-CHEMS) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-DS-0063	DSPE-PEG-VAP	As a somatostatin analogue,VAP is used as a modifier of tumor targeting delivery system because of its high affinity with somatostatin receptor.Dspe-peg-vap was prepared by chemical coupling of α-NH2 of D-phenylalanine with nhs-pegdspe, and then modified paclitaxel loaded nano micelle delivery system with dspe-peg-vap.	price>
R-R-1157	PI3K/Akt/CREB activator 1 CAS No.2708177-73-3	PI3K/Akt/CREB activator 1 (compound AE-18)/CAS No.2708177-73-3 is a potent, orally active PI3K/Akt/CREB activator. PI3K/Akt/CREB activator 1 promotes neuronal proliferation, induced differentiation of Neuro-2a cells into a neuron-like morphology, and accelerated the establishment of axon-dendrite polarization of primary hippocampal neurons through upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway. PI3K/Akt/CREB activator 1 can be used in research of vascular dementia (VaD).	price>
R-PL-0119	PAA-PEG-NH2	Polyacrylic acid-polyethylene glycol-Amine,PAA-PEG-NH2 from ruixi Polyacrylic acid-polyethylene glycol-Amine (PAA-PEG-NH2 ) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-DS-0064	c(RGDDYK)-PEG3400-DSPE	c(RGDDYK) is a model peptide targeting molecule,which can be modified on the surface of liposomes.The immunogenicity and related mechanism of peptide mediated targeting nanoparticles were systematically studied.After intravenous injection of c(RGDDYK) modified liposomes,a large number of antibodies were produced. Repeated injections resulted in the deposition of immune complexes with antibodies in liver,kidney and lung tissues,activating the complement system, releasing allergens and cytokines,resulting in hypersensitivity such as capillary leakage,alveolar protein deposition,inflammatory cell infiltration,kidney and liver congestion,resulting in hypothermia or death in mice.	price>
R-R-1158	Pachymic acid CAS No.29070-92-6	Pachymic acid/CAS No.29070-92-6 is a lanostrane-type triterpenoid from P. cocos. Pachymic acid inhibits Akt and ERK signaling pathways.	price>
R-PL-0120	PAA-PEG-COOH	Polyacrylic acid-polyethylene glycol-carboxyl,PAA-PEG-COOH from ruixi Polyacrylic acid-polyethylene glycol-carboxyl(PAA-PEG-COOH) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-FA-001	FA-PEG-Glycyrrhetinic acid	Folic acid is a kind of water-soluble vitamin,which is named after the rich content of green leaves,also known as pteroylglutamic acid.Glycyrrhetinic acid has the anti-inflammatory effect of butazone or hydrocortisone.	price>
R-DS-0065	LyP-1-PEG3400-DSPE	Cyclopeptide LyP-1 modified liposomes:polypeptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs. It has also been proved by experiments that it can enhance the targeting specificity of drugs,enhance the targeted absorption of drugs,improve the anti-tumor effect,and at the same time,it can improve the original insoluble properties of some small molecule drugs.Peptide carrier targeting technology is known as a new generation of targeted drug development technology.	price>
R-R-1159	Vevorisertib trihydrochloride CAS No.1416775-08-0	Vevorisertib (ARQ 751) trihydrochloride/CAS No.1416775-08-0 is a selective, allosteric, pan-AKT and AKT1-E17K mutant inhibitors. Vevorisertib trihydrochloride potently inhibit phosphorylation of AKT. Vevorisertib trihydrochloride has Kd values of 1.2 nM and 8.6 nM for AKT1 and AKT1-E17K, respectively. Vevorisertib trihydrochloride has IC50 values of 0.55, 0.81, and 1.3 nM for AKT1, AKT2, and AKT3, respectively. Vevorisertib trihydrochloride can be used for the research of cancer.	price>
R-PL-0121	PAA-PEG-MAL	Polyacrylic acid-polyethylene glycol-Maleimide,PAA-PEG-MAL from ruixi Polyacrylic acid-polyethylene glycol-Maleimide(PLLA-PEG-MAL) is a functional amphiphilic block copolymer to prepare targeted micelles or nanoparticles.Block copolymer micelles are widely used in drug delivery applications.PEG is the hydrophilic part and PAAis the hydrophobic part which forms the micelle core wherein the hydrophobic drug is loaded.	price>
R-N-001	Acrylates-PEG-N3	Azide can cyclize with terminal alkyne in the presence of copper catalyst. Acrylates can generate hydrogels.Polyethylene glycol can increase the solubility and stability of drugs,reduce the immunogenicity of peptides and proteins,and inhibit the nonspecific binding of charged molecules on the modified surface.It can modify proteins,peptides and other small molecular materials.It is widely used in pharmaceutical research,drug release,new nano materials research and cell culture.	price>
R-DS-0066	c(RGDyK)-pHA-PEG-DSPE	Peptide mediated targeting drug nanopreparation is an active targeting drug preparation which introduces peptide targeting molecules onto the surface of nano carriers.It can increase the amount of drugs reaching tumor tissue and tumor cells,and achieve the goal of effective treatment of tumor.c(RGDyK) was used as a model peptide targeting molecule,which could be modified on the surface of liposomes.The immunogenicity and related mechanism of peptide mediated targeting nanoparticles were systematically studied.	price>
R-R-1160	Deferoxamine CAS No.70-51-9	Deferoxamine (Deferoxamine B)/CAS No.70-51-9 is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine upregulates HIF-1α levels with good antioxidant activity. Deferoxamine also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. Deferoxamine can be used in studies of diabetes, neurodegenerative diseases as well as anti-cancer and anti-COVID-19.	price>

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