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Catalog	name	Description	price
R-PL-0122	PAA-PEG-NHS	Polyacrylic acid-polyethylene glycol-N-Hydroxysuccinimide,PAA-PEG-NHS from ruixi Polyacrylic acid-polyethylene glycol-N-Hydroxysuccinimide(PLLA-PEG-NHS ) is a functional amphiphilic block copolymer to prepare targeted micelles or nanoparticles.Block copolymer micelles are widely used in drug delivery applications.PEG is the hydrophilic part and PAAis the hydrophobic part which forms the micelle core wherein the hydrophobic drug is loaded.	price>
R-1050-20k	NHS-PEG-CHO	The active ester reacts with primary amine group at ph7-8.5 to form stable amide bond.Polyethylene glycol can increase the solubility and stability of drugs, reduce the immunogenicity of peptides and proteins,and inhibit the nonspecific binding of charged molecules on the modified surface.It can modify proteins, peptides and other small molecular materials.It is widely used in pharmaceutical research,drug release,new nano materials research and cell culture.	price>
R-DS-0067	MC-DA7R-PEG-DSPE	MC-DA7R-PEG-DSPE liposome delivery system can transport BBB and BBTB, target glioma cells,stem cells and tumor neovascularization.After doxorubicin was loaded,MC-DA7R-PEG-DSPE liposomes could effectively inhibit tumor angiogenesis and pseudo angiogenesis,promote apoptosis of glioma cells,and reduce the number of glioma stem cells,thus enhancing the anti glioma effect of doxorubicin.The median survival time of the model animals was longer than that of single targeted molecular modified liposomes (MC-PEG-DSPE liposome and DA7R-PEG-DSPE liposome) 63.6% and 38.5% respectively.	price>
R-R-1161	AS1949490 CAS No.1203680-76-5	AS1949490/CAS No.1203680-76-5 is a potent, orally active, selective SHIP2 phosphatase inhibitor with IC50 values of 0.34, 0.62, 13, >50, >50, and >50 µM for Mouse SHIP2, Human SHIP2, Human SHIP1, Human PTEN, Human synaptojanin, and Human myotubularin, respectively. AS1949490 increases the phosphorylation of Akt, glucose consumption and glucose uptake. AS1949490 activates intracellular insulin signalling pathways. AS1949490 can be used for research of diabetes.	price>
R-PL-0123	PAA-PEG-Alkyne	Polyacrylic acid-polyethylene glycol-Alkyne,PAA-PEG-Alkyne from ruixi Polyacrylic acid-polyethylene glycol-Alkyne(PLLA-PEG-Alkyne ) is a functional amphiphilic block copolymer to prepare targeted micelles or nanoparticles.Block copolymer micelles are widely used in drug delivery applications.PEG is the hydrophilic part and PAAis the hydrophobic part which forms the micelle core wherein the hydrophobic drug is loaded.	price>
QY-C-1101	9,10-anthracene dicarboxylic acid	Ruixi Biotechnology Co.,Ltd.is a well-known biotechnology company in China.At present,its products mainly include synthetic phospholipids,PEG derivatives, block copolymers,gold nanoparticles,magnetic nanoparticles,mesoporous silica, reactive fluorescent dyes,fluorescent quantum dots,dot chemistry and macrocyclic ligands,etc.	price>
R-DS-0068	MC-PEG-DSPE	After doxorubicin was loaded,MC-DA7R-PEG-DSPE liposomes could effectively inhibit tumor angiogenesis and pseudo angiogenesis,promote apoptosis of glioma cells,and reduce the number of glioma stem cells,thus enhancing the anti glioma effect of doxorubicin.The median survival time of the model animals was longer than that of single targeted molecular modified liposomes (MC-PEG-DSPE liposome and DA7R-PEG-DSPE liposome) 63.6% and 38.5% respectively.	price>
R-R-1162	PI3K-IN-46 CAS No.304645-61-2	PI3K-IN-46 (Intermediate 4)/CAS No.304645-61-2 is an intermediate in the synthesis of PI3K inhibitor (2-imino-azolinone-vinyl fused-benzene derivative) that can be used for the research of autoimmune disorders, cardiovascular diseases, and neurodegenerative diseases.	price>
R-PL-0124	PAA-PEG-SH	Polyacrylic acid-polyethylene glycol-Thiol,PAA-PEG-SH from ruixi Polyacrylic acid-polyethylene glycol-Thiol (PLLA-PEG-Thiol ) is a functional amphiphilic block copolymer to prepare targeted micelles or nanoparticles.Block copolymer micelles are widely used in drug delivery applications.PEG is the hydrophilic part and PAAis the hydrophobic part which forms the micelle core wherein the hydrophobic drug is loaded.	price>
R-TD-0010	W-QDs	The water-soluble quantum dots,which are chemically modified,have good biocompatibility,can be connected specifically,and have little harm to organism,and can be labeled and detected in vivo.Fluorescent dyes are generally toxic and biocompatibility is poor.	price>
R-DS-0069	DA7R-PEG-DSPE	After doxorubicin was loaded,MC-DA7R-PEG-DSPE liposomes could effectively inhibit tumor angiogenesis and pseudo angiogenesis,promote apoptosis of glioma cells,and reduce the number of glioma stem cells,thus enhancing the anti glioma effect of doxorubicin.The median survival time of the model animals was longer than that of single targeted molecular modified liposomes (MC-PEG-DSPE liposome and DA7R-PEG-DSPE liposome) 63.6% and 38.5% respectively.	price>
R-R-1163	Pichromene CAS No.883046-50-2	Pichromene (S14161)/CAS No.883046-50-2 is an anticancer agent and weak PI3K inhibitor. Pichromene can effectively inhibit tumor growth in leukemia mouse models and can be used in cancer research.	price>
R-PL-0125	PAA-PEG-Biotin	Polyacrylic acid-polyethylene glycol-Biotin,PAA-PEG-Biotin from ruixi Polyacrylic acid-polyethylene glycol-Biotin(PAA-PEG-Biotin) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-CD-002	DBCO-C4-NHS Ester	DBCO-C4-NHS Ester is an amine-reactive building block used for modification of amine-containing molecule in organic media.The extended 4-carbon atom spacer arm drastically improves solubility of this reagent in commonly used organic solvents such as dichloromethane, chloroform,THF,and ethyl acetate.In addition extended spacer arm significantly improves derivatization efficiency and stability of conjugates.	price>
R-DS-0070	DSPE-PEG-M2pep(YEQDPWGVKWWY)	Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs.The liposome can not stay in the tumor site for a long time after intravenous injection,but the targeted liposome prepared by connecting peptide on the surface of liposome can reach the target site immediately after intravenous injection and stay in the tumor site for a long time. The drug released from the liposome can improve the therapeutic effect of tumor.Polyethylene glycol phospholipid is an excellent material to form liposomes,which can be used for gene transfection, vaccine delivery,drug delivery and targeted drug use.	price>
R-R-1164	Umbralisib R-enantiomer CAS No.1532533-69-9	Umbralisib R-enantiomer (TGR-1202 R-enantiomer)/CAS No.1532533-69-9 is a PI3Kδ inhibitor, which is the less active enantiomer of TGR-1202.	price>
R-PL-0126	PAA-PEG-CHO	Polyacrylic acid-polyethylene glycol-aldehyde,PAA-PEG-CHO from ruixi Polyacrylic acid-polyethylene glycol-aldehyde(PAA-PEG-CHO ) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-R1910	RB-PLGA	Rhodamine B is a synthetic dye with bright pink color.It is red to violet powder, blue red in aqueous solution and red in alcohol solution.It is commonly used as a fluorescent staining agent for cells in the laboratory.	price>
R-DS-0071	GLP-1-PEG-DSPE	Glucagon like peptide-1 (GLP-1) is a kind of brain gut peptide secreted by ileal endocrine cells.It is mainly used as the target of type 2 diabetes drugs.PEG modification makes the previously insoluble peptides less soluble and highly mobile.PEG modification can reduce the filtration of drugs by kidney,reduce its pyrogen,reduce the digestion of protease, and enhance its transport capacity by protecting the body immune system.GLP-1 has two Lys located in the inactive site, which provides great flexibility for modification.	price>
R-R-1165	WYE-687 dihydrochloride CAS No.1702364-87-1	WYE-687 dihydrochloride/CAS No.1702364-87-1 is an ATP-competitive mTOR inhibitor with an IC50 of 7 nM. WYE-687 dihydrochloride concurrently inhibits activation of mTORC1 and mTORC2. WYE-687 also inhibits PI3Kα and PI3Kγ with IC50s of 81 nM and 3.11 μM, respectively.	price>

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