Xi'an ruixi Biological Technology Co

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Catalog	name	Description	price
R-C-032	DSPE-PEG (2000) Carboxylic Acid	Ruixi Biotechnology Co.,Ltd.is a polymer manufacturer and distributor in China. Our company can synthesize PEG derivatives,amphiphilic block copolymers and biodegradable amphiphilic block copolymers,as well as poly amino acid peg block copolymers.The company can provide poly lysines (PLL),poly glutamic acid and poly-L-aspartic Acid polyaspartic acid, poly (l-omnimine) ornithine, poly-L-arginine polyarginine,poly sarcosines and other products.We can also copolymerize these products with PEG, and provide PLL or PGA active groups, including N3,biotin and other active groups.Our PLL polylysine and PGA polyglutamic acid modify different active groups.The active groups can be modified at the end of the straight chain or on the branched chain of the poly amino acid.	price>
R-R-1211	YH-306 CAS No.1373764-75-0	YH-306/CAS No.1373764-75-0 is an antitumor agent. YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway. YH-306 significantly inhibits the migration and invasion of colorectal cancer cells. YH-306 potently suppresses uninhibited proliferation and induces cell apoptosis. YH-306 suppresses the activation of FAK, c-Src, paxillin, and PI3K, Rac1 and the expression of MMP2 and MMP9. YH-306 also inhibita actin-related protein (Arp2/3) complex-mediated actin polymerization.	price>
R-PL-0168	DSPE-PEG-Niacin	1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(polyethylene glycol)-Niacin,DSPE-PEG-Niacin from ruixi Triblock copolymer DSPE-PEG-Niacin .Niacin/Nicotic acid PEG derivatives are a class of bioactive PEGs that can be used to for drug delivery or bioassay development.	price>
R-DS-0021	DPPE-PEG-polypeptide GE11（YHWYGYTPQNVI）	Peptide GE11 is a small molecular peptide obtained by phage peptide library screening technology.It is composed of 11 amino acids (yhwygytpqnvi).GE11 modified micelles are targeting EGFR.The results show that the prepared active targeting EGFR micelles accelerate the cell uptake of drugs,and EGFR is overexpressed on the surface of non-small cell lung cancer.Ge11,a target peptide of EGFR,has been widely used in tumor targeted delivery of genes and drugs.Phospholipid micelles have good tumor tissue penetration,and the introduction of targeted phospholipid micelles may obtain better drug aggregation effect in tumor tissues.	price>
R-C-005	DSPE-PEG (2000) Cyanur	Cyanur PEG-DSPE is an endgroup functionalized PEG-lipid conjugate used for attachment of peptides,antibodies, etc.under mild basic conditions.Proteins can be coupled to this membrane anchor without the need for previous derivatization.	price>
R-R-1212	SAR-260301 CAS No.1260612-13-2	SAR-260301/CAS No.1260612-13-2 is an orally available and selective PI3Kβ inhibitor with an IC50 of 23 nM.	price>
R-PL-0169	DSPE-PEG-ITC	1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(polyethylene glycol)-Isothiocyanate,DSPE-PEG-ITC from ruixi Isothiocyanate is the chemical group –N=C=S, formed by substituting the oxygen in the isocyanate group with a sulfur. The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid.	price>
R-DS-0022	DMPE-PEG-polypeptide GE11（YHWYGYTPQNVI）	GE11,a target peptide of EGFR, has been widely used in tumor targeted delivery of genes and drugs.Phospholipid micelles have good tumor tissue penetration,and the introduction of targeted p.hospholipid micelles may obtain better drug aggregation effect in tumor tissues.Peptide GE11 is a small molecular peptide obtained by phage peptide library screening technology.It is composed of 11 amino acids (yhwygytpqnvi).The results showed that EGFR was over expressed on the surface of NSCLC.	price>
R-C-014	DSPE-PEG-VE	Poly (ethylene glycol) (DSPE) is a combination of phospholipid and polyethylene glycol,which has hydrophilicity and hydrophobicity.Polyethylene glycol phospholipid liposomes can be used for drug delivery,gene transfection and vaccine delivery.Pegylated phospholipids can significantly improve blood circulation time and stabilize drug encapsulation.These materials can also be used for targeted drug delivery by modifying ligands with target surfaces such as antibodies and peptides.	price>
R-R-1213	Deoxyshikonin CAS No.43043-74-9	Deoxyshikonin/CAS No.43043-74-9 increases the expression of VEGF-C and VEGF-A mRNA in HMVEC-dLy, promotes HIF-1α and HIF-1β subunit interaction and binds to specific DNA sequences targeted by HIF. Deoxyshikonin inhibited colorectal cancer (CRC) through the PI3K/Akt/mTOR pathway. Deoxyshikonin has proangiogenesis effect and antitumor activity. Deoxyshikonin is an antibacterial agent against methicillin-resistant S. aureus (MRSA) and S. pneumonia (MIC=17 μg/mL).	price>
R-PL-0170	DSPE-PEG-Tretinoin	1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(polyethylene glycol)-Tretinoin,DSPE-PEG-Tretinoin from ruixi Triblock copolymer DSPE-PEG-Tretinoin .The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid.	price>
R-DS-0023	DOPE-PEG-polypeptide GE11(YHWYGYTPQNVI）	Peptide GE11 is a small molecular peptide obtained by phage peptide library screening technology.It is composed of 11 amino acids (yhwygytpqnvi).Ge11 modified micelles are targeting EGFR.The results show that the prepared active targeting EGFR micelles accelerate the cell uptake of drugs,and EGFR is overexpressed on the surface of non-small cell lung cancer.GE11,a target peptide of EGFR,has been widely used in tumor targeted delivery of genes and drugs.Phospholipid micelles have good tumor tissue penetration,and the introduction of targeted phospholipid micelles may obtain better drug aggregation effect in tumor tissues.	price>
R-C-015	DSPE-PEG-PCL	PEG-PCL can be used in targeted drug research and widely used in protein carrier and ligand crosslinking. Polyethylene glycol polycaprolactone can be used as drug loaded microspheres,microcapsules,vesicles and micelles,which can be used to achieve sustained and controlled release of drugs,and can also be used as tissue engineering scaffold materials with good hydrophilicity.DSPE (1,2-distearyl-sn-glycerin-3-phosphate ethanolamine) is a saturated 18 carbon phospholipid,which is commonly used in the synthesis of liposomes.Polyethylene glycol (PEG)-coupled DSPE is hydrophilic and can be used for drug delivery,gene transfection and biomolecular modification.The PEGylation of phospholipids significantly improved the capsules.	price>
R-R-1214	PI3K-IN-30 CAS No.2281803-22-1	PI3K-IN-30 (compound 6d)/CAS No.2281803-22-1 is a potent PI3K inhibitor with IC50s of 5.1, 136, 30.7 and 8.9 nM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively.	price>
R-PL-0171	DSPE-PEG-ISC	1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(polyethylene glycol)-Isocyanate,DSPE-PEG-ISC from ruixi DSPE PEG has both hydrophilicity and hydrophobility and can be used for drug delivery, gene transfection and vaccine delivery as well. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drugs and are the excellent liposome formation materials. These liposomes can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies, peptides.	price>
R-DS-0024	PLGA-PEG-polypeptide GE11(YHWYGYTPQNVI）	Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs.Peptide carrier targeting technology is known as a new generation of targeted drug development technology.	price>
R-C-016	DSPE-PEG-PLA	PEG-PLA can be used in the research of targeted drugs and the crosslinking of protein carriers and ligands.Polyethylene glycol polylactic acid can be used as drug loaded microspheres,microcapsules,vesicles and micelles,which can be used to achieve drug sustained-release and controlled-release.It can also be used as a tissue engineering scaffold with good hydrophilicity.DSPE(1,2-distearyl-sn-glycerin-3-phosphate ethanolamine) is a saturated 18 carbon phospholipid,which is commonly used in the synthesis of liposomes.Polyethylene glycol (PEG) - coupled DSPE is hydrophilic and can be used for drug delivery,gene transfection and biomolecular modification.	price>
R-R-1215	Buparlisib Hydrochloride CAS No.1312445-63-8	Buparlisib Hydrochloride (BKM120 Hydrochloride)/CAS No.1312445-63-8 is a pan-class I PI3K inhibitor, with IC50 of 52 nM/166 nM/116 nM/262 nM for p110α/p110β/p110δ/p110γ, respectively.	price>
R-PL-0172	Cholesterol-PEG-Phenyl	Cholesterol-polyethylene glycol-Phenyl,Cholesterol-PEG-Phenyl from ruixi Cholesterol is one of the important constituent of all membranes. It is made up of a hydrophobic, planar, a polar hydroxyl group, fused-ring nucleus and a short hydrocarbon tail.	price>
R-DS-0025	PCL-PEG-polypeptide GE11(YHWYGYTPQNVI）	Poly(ε-caprolactone)-Polyethylene glycol-polypeptide GE11(YHWYGYTPQNVI） ,GE11,a target peptide of EGFR,has been widely used in tumor targeted delivery of genes and drugs.Phospholipid micelles have good tumor tissue penetration,and the introduction of targeted p.hospholipid micelles may obtain better drug aggregation effect in tumor tissues.Peptide GE11 is a small molecular peptide obtained by phage peptide library screening technology.It is composed of 11 amino acids (yhwygytpqnvi).The results showed that EGFR was over expressed on the surface of NSCLC.	price>

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