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R-R-1443 Trabectedin-d3 Trabectedin D3 (Ecteinascidin 743 D3) is deuterium labeled Trabectedin. Trabectedin is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbone cleavage and cancer cells apoptosis, and increases the generation of ROS in MCF-7 and MDA-MB-453 cells. Trabectedin has tje potential for soft tissue sarcoma and ovarian cancer treatment. price>
R-OR-344 CY3-Polyglycine Cyanine3-Polyglycine CY3-Polyglycine from ruixi Cyanine3 labeled Polyglycine.Polyglycine is a substance used to modify carbon fiber microelectrode differential pulse voltammetry for the determination of uric acid.Polyglycine has been used as an external intensity standard for measuring cross polarization (CP) nuclear magnetic resonance (NMR) spectrum measurements and ion mobility mass spectrometry. It is suitable for use as a model for UV resonance Raman spectroscopy studies. price>
R-M-020 ZIF-71,zeolitic imidazolate framework-71 ZIF-71,zeolitic imidazolate framework-71 from ruixi.Zif-71 has super hydrophobic pore channel and very flexible pore structure, which can be used as an excellent filler for organic pervaporation membrane of bioethanol recovery.Zif-71 membrane has good separation performance for ethanol water mixture. price>
R-R-1444 Toyocamycin CAS No.606-58-6 Toyocamycin (Vengicide)/CAS No.606-58-6 is an adenosine analog produced by Streptomyces diastatochromogenes, acts as an XBP1 inhibitor. Toyocamycin blocks RNA synthesis and ribosome function, and induces apoptosis. Toyocamycin affects IRE1α-XBP1 pathway, and inhibits XBP1 mRNA cleavage with an IC50 value of 80 nM with affecting IRE1α auto-phosphorylation. Toyocamycin specifically inhibits CDK9 with an IC50 value of 79 nM. price>
R-OR-345 CY3-Poly-L-valine Cyanine3-Poly-L-valine CY3-Poly-L-valine from ruixi Cyanine3 labeled Poly-L-valine.Ruixi biology provides a variety of fluorescein labeled compounds. For example, fluorescein FITC labeled compounds, rhodamine B-labeled compounds, Cy3, cy3.5, Cy5, Cy5, cy7, cy7.5 and other labeled compounds. Our technology is gradually mature, and our products are recognized by universities at home and abroad. Welcome to consult our products. price>
R-M-021 ZIF-224,zeolitic imidazolate framework-224 ZIF-224,zeolitic imidazolate framework-224 from ruixi.ZIF is the framework material of zeolites imidazole ester, which is a porous crystal material.ZIF is a potential active inorganic filler for gas separation membrane.ZIF based materials can be used in low energy gas separation, catalytic nano reactor and sensor technology. price>
R-R-1445 Damnacanthal CAS No.477-84-9 Damnacanthal/CAS No.477-84-9 is an anthraquinone isolated from the root of Morinda citrifolia. Damnacanthal is a highly potent, selective inhibitor of p56lck tyrosine kinase activity. Natural Damnacanthal inhibits p56 lck autophosphorylation and phosphorylation of exogenous substrates with IC50s of 46 nM and 220 nM, respectively. Damnacanthal is a potent inducer of apoptosis with anticancer activity. Damnacanthal also has antinociceptive, anti-inflammatory effects in mice and anti-fungal activity against Candida albicans. price>
R-OR-346 CY3--Poly-L-Arginine Cyanine3-Poly-L-Arginine CY3--Poly-L-Arginine from ruixi Cyanine3 labeled Poly-L-Arginine.Poly-L-arginine hydrochloride is a positively charged synthetic polyamino acid having one HCl per arginine unit. It is a crystalline solid soluble in water. Applications for poly-L-arginine hydrochloride include the layer-by-layer deposition techniques and the complexation with nucleic acids for gene expression. price>
R-M-022 ZIF-14,zeolitic imidazolate framework-14 ZIF-14,zeolitic imidazolate framework-14 from ruixi.Zif-14 is a kind of gas storage and adsorption material, which can be used as drug carrier for drug adsorption and release.ZIF is the framework material of zeolites imidazole ester, which is a porous crystal material.ZIF is a potential active inorganic filler for gas separation membrane.ZIF based materials can be used in low energy gas separation, catalytic nano reactor and sensor technology. price>
R-R-1446 SC144 hydrochloride CAS No.917497-70-2 SC144 hydrochloride/CAS No.917497-70-2 is a first-in-class, orally active gp130 (IL6-beta) inhibitor. SC144 hydrochloride binds gp130, induces gp130 phosphorylation (S782) and deglycosylation, abrogates Stat3 phosphorylation and nuclear translocation, and further inhibits the expression of downstream target genes. SC144 hydrochloride shows potent inhibition of gp130 ligand-triggered signaling. SC144 hydrochloride induces apoptosis in human ovarian cancer cells. price>
R-OR-347 CY5.5-Poly-Lysines Cyanine5.5-Poly-Lysines CY5.5--Poly-Lysines from ruixi Cyanine5.5(CY5.5)labeled Poly-Lysines.RUIXIBIOTECH provides a variety of chemically functionalized and bioconjugated Poly-L-lysine with different functionality. These functional polylysine products were purified by size chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo. price>
R-M-023 ZIF-15,zeolitic imidazolate framework-15 ZIF-15,zeolitic imidazolate framework-15 from ruixi.ZIF is the framework material of zeolites imidazole ester, which is a porous crystal material.ZIF is a potential active inorganic filler for gas separation membrane.ZIF based materials can be used in low energy gas separation, catalytic nano reactor and sensor technology. price>
R-R-1447 Sotetsuflavone CAS No.2608-21-1 Sotetsuflavone/CAS No.2608-21-1 is a flavonoid that can be isolated from Cycas revolute. Sotetsuflavone inhibits migration and invasion of A549 cells by reversing EMT, and induces cell apoptosis and autophagy. Sotetsuflavone inhibits HIF-1α, VEGF, angiostatin, MMP-9, and MMP-13 expression in A549 cells. price>
R-OR-348 CY5.5--Poly-L-aspartic acid Cyanine5.5-Poly-L-aspartic acid CY5.5--Poly-L-aspartic acid from ruixi Cyanine5.5(CY5.5)labeled Poly-L-aspartic acid.Polyaspartic acid (PASP) is a kind of poly amino acids. Polyaspartic acid is easily broken by microorganisms and fungi because of the peptide bond on its main chain. The final degradation products are harmless ammonia, carbon dioxide and water. price>
R-M-024 ZIF-60,zeolitic imidazolate framework-60 ZIF-60,zeolitic imidazolate framework-60 from ruixi.ZIF is the framework material of zeolites imidazole ester, which is a porous crystal material.ZIF is a potential active inorganic filler for gas separation membrane.ZIF based materials can be used in low energy gas separation, catalytic nano reactor and sensor technology. price>
R-R-1448 Rilmenidine hemifumarate CAS No.207572-68-7 Rilmenidine hemifumarate/CAS No.207572-68-7, an innovative antihypertensive agent, is an orally active, selective I1 imidazoline receptor agonist. Rilmenidine hemifumarate is an alpha 2-adrenoceptor agonist. Rilmenidine hemifumarate induces autophagy. Rilmenidine hemifumarate acts both centrally by reducing sympathetic overactivity and in the kidney by inhibiting the Na+/H+ antiport. Rilmenidine hemifumarate modulates proliferation and stimulates the proapoptotic protein Bax thus inducing the perturbation of the mitochondrial pathway and apoptosis in human leukemic K562 cells . price>
R-OR-349 CY5.5-Poly-Glutamic Acid Cyanine5.5-Poly-Glutamic Acid CY5.5--Poly-Glutamic Acid from ruixi Cyanine5.5(CY5.5)labeled Poly-Glutamic Acid. Polyglutamic acid (γ - PGA), also known as natto gum and polyglutamic acid, is a kind of water-soluble, biodegradable, non-toxic biopolymer produced by microbial fermentation. γ - PGA polyglutamic acid is a viscous substance. price>
R-M-026 ZIF-268,zeolitic imidazolate framework-268 ZIF-268,zeolitic imidazolate framework-268 from ruixi.ZIF is the framework material of zeolites imidazole ester, which is a porous crystal material.ZIF is a potential active inorganic filler for gas separation membrane.ZIF based materials can be used in low energy gas separation, catalytic nano reactor and sensor technology. price>
R-R-1449 GW779439X CAS No.551919-98-3 GW779439X/CAS No.551919-98-3 is a pyrazolopyridazine identified in an inhibitor of the S. aureus PASTA kinase Stk1. GW779439X potentiates the activity of β-lactam antibiotics against various MRSA and MSSA isolates, some even crossing the breakpoint from resistant to sensitive. GW779439X is an AURKA inhibitor and induces apoptosis by the caspases 3/7 pathway. MRSA:methicillin-resistant S. aureus; MSSA: methicillin-sensitive S. aureus price>
R-OR-350 CY5.5-Poly-L-serine Cyanine5.5-Poly-L-serine CY5.5-Poly-L-serine from ruixi Cyanine5.5(CY5.5)labeled Poly-L-serine.Ruixi biology provides a variety of fluorescein labeled compounds. For example, fluorescein FITC labeled compounds, rhodamine B-labeled compounds, Cy3, cy3.5, Cy5, Cy5, cy7, cy7.5 and other labeled compounds. Our technology is gradually mature, and our products are recognized by universities at home and abroad. Welcome to consult our products. price>