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Catalog	name	Description	price
R-R-1574	Alrizomadlin CAS No.1818393-16-6	Alrizomadlin (APG-115)/CAS No.1818393-16-6 is an orally active MDM2 protein inhibitor binding to MDM2 protein with IC50 and Ki values of 3.8 nM and 1 nM, respectively. Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-dependent manner.	price>
R-OR-562	PEI-PDEA	Polyethyleneimine (PEI), also known as polyaazacyclopropane, is a kind of water-soluble polymer. Under certain conditions, polyethyleneimine solid materials can absorb a large amount of carbon dioxide in humid air, and the separation process is very convenient. Carbon dioxide can be permanently sealed in polyethyleneimine solid materials, and can also be extracted and used in other fields.	price>
R-UYH470	Oil soluble Upconverting Nanoparticle, Core-shell	Oil dispersible upconverting nanoparticles(UCNPS),Oil soluble Upconverting Nanoparticle, Core-shell from ruixi.The upconversion nanoparticles, which use near-infrared continuous laser as the excitation source, have deep light penetration depth, no background fluorescence interference, and almost no damage to biological tissues.Oil soluble modified up conversion nanoparticles have good stability and can be used in the study of drug loaded imaging system.	price>
R-M-153	Insulin B (22-25),CAS: 34367-73-2	Insulin B (22-25),H-Arg-Gly-Phe-Phe-OH is a kind of diabetes peptides.According to data from the International Diabetes Federation,more than 422 million people around the world suffer from diabetes mellitus, a chronic metabolic disorder characterized by hyperglycemia. Diabetes mellitus can be divided into two main types, type 1 or insulin-dependent diabetes mellitus (IDDM) and type 2, or non-insulin-dependent diabetes mellitus (NIDDM). The absolute lack of insulin, due to destruction of the insulin producing pancreaticβ-cells,is the particular disorder in type 1 diabetes.Type 2 diabetes is mainly characterized by the inability of cells to respond to insulin. The condition affects mostly the cells of muscle and fat tissue, and results in a condition known as “insulin resistance”.	price>
R-M-194	cGKI Kinase Inhibitor Peptide	The peptide is a synthetic inhibitor of the cGKI protein kinase. The sequence corresponds to the mutated S32A phosphorylation site analog within residues 29-35 of human histone H2B. The cGKI kinase belongs to the AGC Ser/Thr family, cGMP subfamily, and has two isoforms, alpha and beta, that become active upon homodimerization and cGMP binding.	price>
R-R-1575	Hydroxysafflor yellow A CAS No.78281-02-4	Hydroxysafflor yellow A (Safflomin A)/CAS No.78281-02-4 is a natural product of flavonoids isolated from safflower. Hydroxysafflor yellow A can inhibit cell proliferation and promote apoptosis through the autophagy pathway. Hydroxysafflor yellow A has anti-inflammatory, antioxidant and antitumor effects. Hydroxysafflor yellow A can be used in the study of cardiovascular disease.	price>
R-OR-563	MANNOSE-BSA	ANNOSE-BSA ，MANNOSE-Bovine serum albumin from ruixi.Mannose coupled bovine serum albumin.Bovine serum albumin is widely used in biochemical experiments.BSA is generally used as a stabilizer to limit the enzyme or modified enzyme in the preservation solution and reaction solution, because some enzymes are unstable or low activity at low concentration. When BSA is added, it may play a role of "protection" or "carrier".	price>
R-UW365	NaYF4,Yb,Tm@NaYF4,Water soluble Upconverting Nanoparticle, Core-shell,EX:808nm	Water dispersible upconverting nanoparticles, absorbance 808 nm,Water soluble Upconverting Nanoparticle, Core-shell from ruixi.The upconversion nanoparticles, which use near-infrared continuous laser as the excitation source, have deep light penetration depth, no background fluorescence interference, and almost no damage to biological tissues.Water soluble up conversion nanoparticles have good stability and can be used in the study of drug loaded imaging system.	price>
R-M-154	XPC Peptide	Xeroderma pigmentosum group C-complementing protein (XPC) is involved in DNA excision repair by recognizing DNA damage and altering chromatin structure for damage-processing enzymes. Defects in XPC are a cause of xeroderma pigmentosum complementation group C characterized by solar sensitivity and skin cancer predisposition.	price>
R-M-195	Trypsin Substrate Peptide	This peptide is a fluorogenic substrate for trypsin, a peptidase S1 family members that cleaves at Arg-Xaa and Lys-Xaa sites within proteins. The peptide is labeled with rhodamine 110, a highly fluororescent dye upon substrate cleavage (Abs/Em = 497/520 nm).	price>
R-R-1576	Taurodeoxycholic acid CAS No.516-50-7	Taurodeoxycholic acid/CAS No.516-50-7, a bile acid, stabilizes the mitochondrial membrane, decreases free radical formation. Taurodeoxycholic acid inhibits apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation.	price>
R-OR-564	mPEG2K-hyd-PEI25K	methoxy polyethylene glycol 2k-hydrazone-Polyethyleneimine,mPEG2K-hyd-PEI25K from ruixi.One end of the hydrazone bond is connected with the methoxy polyetherylene glycol, and the other end is connected with the polyetherimide.Polyetherimide is called PEI for short. Pei has a strong high-temperature stability, so the superior thermal stability of Pei can be used to make high-temperature and heat-resistant devices. Pei also has good flame retardancy, chemical resistance and electrical insulation properties.	price>
R-M-155	Tyr-Specific Protein Kinase Inhibitor Peptide	This peptide is an inhibitor for tyrosine protein kinases such as EGFR and Src subfamily members (IC50=7.5 mM for pp60 v-src).The sequence corresponds to residues 140-160 of the proto-oncogene tyrosine protein kinase Src (c-Src).	price>
R-M-196	Ser25 PKC [19-31] Peptide	This is a peptide derived from the pseudosubstrate regulatory domain of PKC α residues (19-31) with alanine being replaced with serine at position 25.This peptide is a pseudosubstrate for a number of serine/threonine kinases, including protein kinase A (PKA), protein kinase B (PKB), protein kinase C (PKC), protein kinase CHK1, and glycogen synthase kinase 3 (GSK3) different isoforms. The peptide sequence is derived from the residues 19-31 of human protein kinase C isoforms alpha and beta, which contains the R-X-X-S/T consensus motif for Ser/Thr kinases that phosphorylate the Ser25 within this peptide.	price>
R-R-1577	Piclidenoson CAS No.152918-18-8	Piclidenoson (IB-MECA)/CAS No.152918-18-8 is a first-in-class, orally active and selective A3 adenosine receptor (A3AR) agonist. Piclidenoson exhibits antiproliferative effect and induces apoptosis in different cancer cell types like melanoma, leukemia. Piclidenoson can be used for the research of autoimmune inflammatory diseases and COVID-19.	price>
R-OR-565	Hemin-NHS	Hemin Chloride-N-hydroxysuccinimide，hemin-NHS from ruixi.Heme chloride is the purification form of natural heme in vitro. Hemin is widely used in medicine, food, chemical industry, health products, construction and cosmetics industry. In the pharmaceutical industry, it can be used as semi synthetic bilirubin raw material, and can be used to prepare anticancer drugs; in clinical, it can be made into heme iron supplement; in the cosmetics industry, it is an important raw material	price>
R-M-156	Tyrosine Protein Kinase Substrate Peptide	This peptide is a substrate for tyrosine protein kinases such as EGFR and Src subfamily members. The sequence derives from the residues 412-422 of the Tyr-419 tyrosine autophosphorylation site of the proto-oncogene tyrosine protien kinase Src (c-Src).	price>
R-M-197	S6 Kinase Substrate [229-239] Peptide	Ribosomal protein S6 is the major substrate of protein kinases in eukaryote ribosomes. The phosphorylation is stimulated by growth factors, tumor promoting agents and mitogens and the dephosphorylation by growth arrest. The 229-239 peptide contain two phosphorylation sites, Ser235 and Ser236.	price>
R-R-1578	Citreoviridin CAS No.25425-12-1	Citreoviridin/CAS No.25425-12-1, a toxin from Penicillium citreoviride NRRL 2579, inhibits brain synaptosomal Na+/K+-ATPase whereas in microsomes, both Na+/K+-ATPase and Mg2+-ATPase activities are significantly stimulated in a dose-dependent manner. Citreoviridin inhibits cell proliferation and enhances apoptosis of human umbilical vein endothelial cells.	price>
R-OR-566	PLGA25K-PEG5K-choline	Poly(lactic-co-glycolic acid)25k-polyethylene glycol5k-choline, PLGA25000-PEG5000-choline from ruixi.Choline is a positively charged tetravalent base, which is the component of all biofilms and the precursor of acetylcholine in cholinergic neurons. Choline promotes brain development, memory and information transmission.	price>

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