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R-M-157 [Val5] Angiotensin II Peptide Angiotensin II is the physiologically active form and regulates both the volume and the mineral balance in the body through vasoconstriction, aldosterone release, sodium uptake and thirst stimulation. Angiotensin II is a natural ligand for angiotensin II type 1 receptors. [Val5] Angiotensin II peptide is an angiotensin II analog that is an agonist for AT1 angiotensin receptors. price>
R-M-198 KL-1 Peptide KL-1 Peptide corresponds to aa 185-196 of Kit Ligand (KITLG, KL) also known as Stem Cell Factor (SCF). A soluble form (sKITLG) is produced by proteolytic processing of transmembrane KITLG at aa190. KL-1 peptide is used as a substrate for proteases such as furin. SCF stimulates the proliferation of mast cells, augments the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture, and mediates cell-cell adhesion. SCF acts synergistically with other cytokines such as interleukins. price>
R-R-1579 Perhexiline maleate CAS No.6724-53-4 Perhexiline maleate/CAS No.6724-53-4 is an orally active CPT1 and CPT2 inhibitor that reduces fatty acid metabolism. Perhexiline maleate induces mitochondrial dysfunction and apoptosis in hepatic cells. Perhexiline maleate can cross the blood brain barrier (BBB) and shows anti-tumor activity. Perhexiline maleate can be used in the research of cancers, and cardiovascular disease like angina. price>
R-DZ0190 Chitosan-β-Cyclodextrin Chitosan-β-Cyclodextrin, Chitosan-β-CD from ruixi.Chitosan is a product of N-deacetylation of chitosan. Chitin, chitosan and cellulose have similar chemical structure. It is widely used in food additives, cosmetics, antibacterial agents, medical fibers, medical dressings, artificial tissue materials, drug slow-release materials, gene transfer carriers, biomedical fields, medical absorbable materials, medical and Many fields such as drug development and other daily chemical industries.β - cyclodextrin is widely used in pharmaceutical excipients and food additives. price>
R-M-158 Cyclo(-Pro-Tyr),CAS:4549-02-4 The host-specific phytotoxin cyclo(Pro-Tyr),CAS:4549-02-4 produced by Alternaria alternata on spotted knapweed is an ideal prototype for creating a safe and an environmentally friendly antiknapweed herbicide. Furthermore, this cyclic dipeptide induced a high degree of phosphorylation of histones. price>
R-M-199 Elastase Substrate Peptide This peptide is a fluorogenic substrate for elastase, a peptidase S1 family member that cleaves at Ala-Xaa sites within proteins, including elastin. The peptide is labeled with rhodamine 110, a highly fluororescent dye upon substrate cleavage (Abs/Em = 497/520 nm). price>
R-R-1580 Mensacarcin CAS No.808750-39-2 Mensacarcin/CAS No.808750-39-2, a highly complex polyketide, strongly inhibits cell growth universally in cancer cell lines and potently induces apoptosis in melanoma cells. Mensacarcin targets to mitochondria, affects energy metabolism in mitochondria, and activates caspase-dependent apoptotic pathways. Mensacarcin, an antibiotic, can be used as a cytotoxic component of antibody-drug conjugates (ADCs). price>
R-OR-567 CHOL-PEG2000-NAcPGPv Cholesterol-polyethylene glycol2k-NAcPGPv,CHOL-PEG2000-NAcPGPv from ruixi.N-acetylproline-glycine-proline is a matrix derived chemokine produced by collagen degradation. price>
R-M-159 Cyclo(-Leu-Pro),CAS:2873-36-1 Cyclo(Leu-Pro) showed antibacterial activity. Yan et al. observed that Cyclo(Leu-Pro) produced by Achromobacter xylosoxidans inhibited aflatoxin production by Aspergillus parasiticus. The diketopiperazine was shown to inhibit catecholamine release in vitro. It could play a role in the hypothalamic modulation of appetite suppressant circuitry. Cyclo(L-Leu-L-Pro) is a diketopiperazine metabolite and it has been isolated from various bacterial and fungal species including Streptomyces. It is active against twelve strains of vancomycin-resistant enterococci (VRE) and also inhibits growth of K562, HL-60, and U937 leukemia cells in a concentration-dependent manner when used at concentrations of 1-500 µg/ml. price>
R-M-200 Cathepsin L Substrate Peptide This peptide is a fluorogenic substrate for cathepsin L and plasmin, peptidase C1 family members that cleave at Arg-Xaa and Lys-Xaa sites within proteins. The peptide is labeled with rhodamine 110, a highly fluororescent dye upon substrate cleavage (Abs/Em = 497/520 nm). price>
R-R-1581 Ecdysone CAS No.3604-87-3 Ecdysone (α-Ecdysone)/CAS No.3604-87-3, a major steroid hormone in insects and herbs, triggers mineralocorticoid receptor (MR) activation and induces cellular apoptosis. Ecdysone plays essential roles in coordinating developmental transitions and homeostatic sleep regulation through its active metabolite 20-hydroxyecdysone (Crustecdysone; 20E; HY-N6979). price>
R-OR-5677 NGR-PEG2K-PLA Poly(D,L-lactide)-Polyethylene glycol2k-NGR,Sequence number of NgR peptide:Asparagic acid-Arginine-Glycine,NGR-PEG2K-PLA from ruixi.NgR peptide is a kind of target peptide which can bind to CD13 receptor on tumor neovascular endothelial cells. It can locate liposome in tumor tissue, make the drugs in liposome concentrate in tumor site, so as to improve tumor effect. price>
R-M-160 Cyclo(-Leu-Phe),CAS: 7280-77-5 Cyclo(L-phenylalanyl-L-leucyl),Cyclo(-Leu-Phe) is a member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione in which one hydrogen at position 3 and one hydrogen at position 6 are replaced by benzyl and isobutyl groups (the 3S,6S-diastereomer). It has a role as a metabolite. This diketopiperazine is converted into the antibacterial dehydropeptide albonoursin by cyclo(Leu-Phe) oxidase from S. albulus KO-23. price>
R-M-201 CaMKII Substrate Peptide This peptide is a substrate (Km = 7.5 mM) for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family. The sequence derives from the residues 1-10 of the glycogen synthase containing a phosphorylation site at Ser-7 within the R-X-X-S/T consensus site and is amidated at the C-terminus end. CaMKII is a prominent kinase in the central nervous system that functions in long-term potentiation and neurotransmitter release. Phosphorylation of the substrate is calcium and calmodulin dependent. price>
R-R-1582 Melatonin-d4 CAS No.66521-38-8 Melatonin-d4/CAS No.66521-38-8 is deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Antioxidative and anti-inflammatory properties. Melatonin is a selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation. price>
R-OR-568 PAE10K-PEG5K-glutamine(Connected by carboxyl group) poly(β-amino esters)10k-polyethylene glycol5k-glutamine,PAE10000-PEG5000-glutamine(Connected by carboxyl group) from ruixi.Glutamine, scientific name 2-amino-4-carbamoyl butyric acid, English glutamine (Gln).Poly (β - aminoester) is a kind of drug carrier with pH sensitivity, low toxicity, simple synthesis method and various structures. It has a broad medical prospect in tumor targeting drug system. price>
R-M-161 cyclo-GP,CAS :3705-27-9 Cyclo(Gly-Pro) has been detected in rat brain. In the passive avoidance test in rats, synthetic cycloprolylglycine showed 76% antiamnesic activity.Cyclo(Gly-L-Pro) is a cyclodipeptide isolated from the roots of Panax notoginseng (Burk.)F.H.Chen. Cyclo(Gly-L-Pro) was reported to inhibit TNF-α release, IL-1β and IL-6 mRNA expression and NO production. price>
R-M-202 Calcineurin Substrate Peptide The calcineurin substrate peptide corresponds to a sequence from the regulatory RII subunit of cAMP-dependent protein kinase. Calcineurin substrate can be used for assaying protein phosphatase-2B (calcineurin) activity. price>
R-R-1583 MYC-RIBOTAC MYC-RIBOTAC is a ribonuclease-targeting chimera (RIBOTAC) to MYC internal ribosome entry site (IRES).MYC-RIBOTAC contains a MYC mRNA-binder and a small molecule that recruits and locally activates RNase L1 and decreases the mRNA and protein expression levels of MYC, induces apoptosis. MYC-RIBOTAC can be used for anticancer research. price>
R-DZP003 Poly(DMA-co-NAS)MW:7500-8000 Ruixi Biotechnology Co., Ltd. is a well-known biotechnology company. Our company focuses on the production and sales of scientific research level drug delivery and drug nano targeting products. At present, our products mainly include synthetic phospholipids, PEG derivatives, block copolymers, nano gold, magnetic nanoparticles, mesoporous silica, reactive fluorescent dyes, fluorescent quantum dots, click Chemistry and macrocyclic ligands, etc. price>