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R-R-1599 Eriocitrin CAS No.13463-28-0 Eriocitrin/CAS No.13463-28-0 is a flavonoid isolated from lemons that is a powerful antioxidant. Eriocitrin inhibits the proliferation of liver cancer cells by arresting the cell cycle in the S phase by upregulating p53, cyclin A, cyclin D3 and CDK6. Eriocitrin triggers apoptosis by activating intrinsic signaling pathways involving mitochondria. price>
R-OR-573 DSPE-PEG2k-anti-Flt1 ,(Sequence of polypeptide:GNQWFI) 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(polyethylene glycol)-anti-Flt1,DSPE-PEG2k-anti-Flt1 from ruixi.Although the peptide can not directly inhibit the proliferation or migration of endothelial cells, it can significantly inhibit the binding of VEGF or PIGF to the receptor, and block the pathway of neovascularization from the beginning. price>
R-M-218 [DPhe7] Bradykinin Peptide [DPhe7] Bradykinin Peptid from ruixi.Bradykinin is a peptide that exhibits natriuretic, antioxidative, vasodilatory, and pro-angiogenic activities. Bradykinin stimulates bradykinin receptors and increases PLC activity, decreasing ENaC open probability, inhibiting distal nephron Na+ transport, and inducing natriuresis. In vitro, bradykinin decreases H2O2-induced senescence, increases activity of superoxide dismutase (SOD), and suppresses DNA damage, ROS production, and NADPH oxidase activity. Additionally, bradykinin increases expression of VEGF and promotes tube formation in prostate cancer cells. price>
R-R-1600 Humulone CAS No.26472-41-3 Humulone (α-Lupulic acid)/CAS No.26472-41-3, a prenylated phloroglucinol derivative, is a potent cyclooxygenase-2 (COX-2) inhibitor. Humulone acts as a positive modulator of GABAA receptor at low micromolar concentrations. Humulone is an inhibitor of bone resorption. Humulone possesses antioxidant, anti-angiogenic and apoptosis-inducing properties. price>
R-OR-580 PCL5000-Hyd--PEG5000-DOTA Poly(ε-caprolactone)5k-hydrazone-Polyethylene glycol5k-DOTA,PCL5000-Hyd--PEG5000-DOTA from ruixi.Ruixi Biotechnology Co., Ltd. is a well-known biotechnology company. Our company focuses on the production and sales of scientific research level drug delivery and drug nano targeting products. At present, our products mainly include synthetic phospholipids, PEG derivatives, block copolymers, nano gold, magnetic nanoparticles, mesoporous silica, reactive fluorescent dyes, fluorescent quantum dots, click Chemistry and macrocyclic ligands, etc. price>
R-M-219 [Des-Pro2] Bradykinin Peptide [Des-Pro2] Bradykinin Peptide from ruixi.Bradykinin is a peptide that exhibits natriuretic, antioxidative, vasodilatory, and pro-angiogenic activities. Bradykinin stimulates bradykinin receptors and increases PLC activity, decreasing ENaC open probability, inhibiting distal nephron Na+ transport, and inducing natriuresis. In vitro, bradykinin decreases H2O2-induced senescence, increases activity of superoxide dismutase (SOD), and suppresses DNA damage, ROS production, and NADPH oxidase activity. price>
R-R-1601 Everolimus CAS No.159351-69-6 Everolimus (RAD001)/CAS No.159351-69-6, a rapamycin derivative, is a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to produce an immunosuppressive complex. Everolimus inhibits tumor cell proliferation and induces apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activity. price>
R-OR-581 Coumarin-Hyaluronic acid Coumarin labeled hyaluronic acid.Coumarin is the general name of o-hydroxycinnamic acid lactone, which has sweet fragrance.Hyaluronic acid is a kind of acid mucopolysaccharide, which has many important physiological functions in the body due to its unique molecular structure and physical and chemical properties price>
R-M-220 [Des-Gly10, D-Leu6, ProNHEt9] LH-RH Leuprolide Peptide Leuprolide (leuprorelin) is a peptide analog of gonadotropin-releasing hormone (GnRH) that binds and activates the GnRH1 receptor. Leuprorelin modulates fertility by stimulating release of reproductive hormones. Leuprorelin also prevents stress-induced immunosuppression in animal models. Additionally, leuprorelin exhibits anticancer activity, inhibiting proliferation of prostate cancer cells in vitro. Leuprorelin also inhibits proliferation of endometrial cancer cells by suppressing expression of human telomerase reverse transcriptase (hTERT). In endometrial cells, leuprorelin induces apoptosis by increasing levels of Bax and FasL and decreasing levels of Bcl-2. Leuprorelin also exhibits anti-angiogenic activity, decreasing production of VEGF-A and IL-1β in endothelial cells. price>
R-R-1602 Lexibulin CAS No.917111-44-5 Lexibulin (CYT-997)/CAS No.917111-44-5 is a potent and orally active tubulin polymerisation inhibitor with IC50s of 10-100 nM in cancer cell lines; with potent cytotoxic and vascular disrupting activity in vitro and in vivo. Lexibulin induces cell apoptosis and induces mitochondrial ROS generation in GC cells. price>
R-OR-582 C16-TK-COOH C16-thioketal-carboxyl,C16-TK-COOH from ruixi.Ruixi Biotechnology Co., Ltd. is a well-known biotechnology company. Our company focuses on the production and sales of scientific research level drug delivery and drug nano targeting products. At present, our products mainly include synthetic phospholipids, PEG derivatives, block copolymers, nano gold, magnetic nanoparticles, mesoporous silica, reactive fluorescent dyes, fluorescent quantum dots, click Chemistry and macrocyclic ligands, etc. price>
R-M-221 [D-Trp11] Neurotensin (NT) Peptide Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscles. price>
R-R-1603 Isosilybin A CAS No.142796-21-2 Isosilybin A/CAS No.142796-21-2, a flavonolignan isolated from silymarin, has anti-prostate cancer (PCA) activity. Isosilybin A inhibits proliferation and induces G1 phase arrest and apoptosis in cancer cells, which activates apoptotic machinery in PCA cells via targeting Akt-NF-κB-androgen receptor (AR) axis. price>
R-OR-583 PINPAM2.5K-PLGA6K-PEG1K PINPAM2500-Poly(lactic-co-glycolic acid)6000-Polyethylene glycol1000,Ruixi Biotechnology Co., Ltd. is a well-known biotechnology company. Our company focuses on the production and sales of scientific research level drug delivery and drug nano targeting products. At present, our products mainly include synthetic phospholipids, PEG derivatives, block copolymers, nano gold, magnetic nanoparticles, mesoporous silica, reactive fluorescent dyes, fluorescent quantum dots, click Chemistry and macrocyclic ligands, etc. price>
R-M-222 [Arg8] Vasotocin Peptide [Arg8] vasotocin is a 9-mer peptide corresponding to aa20-28 sequence from the vasotocin-neurophysin VT precursor. Vasotocin is an antidiuretic hormone present in the neurohypophysis. Vasotocin is related to vasopressin and oxytocin hormones with similar oxytocic and vasoconstrictor properties. [Arg8]-Vasotocin is a hormone present in the neurohypophysis of nonmammalian vertebrates that is related to vasopressin and oxytocin. The demonstration of vasotocin in the mammalian pineal gland, subcommissural organ and fetal pituitary gland by bioassay has led to hypotheses regarding the function of this hormone in various reproductive processes. price>
R-R-1604 Difopein TFA Difopein (TFA), a specific and competitive inhibitor of 14-3-3 protein (a highly conserved eukaryotic regulatory molecule), blocking the ability of 14-3-3 to bind to target proteins and inhibits 14-3-3/Ligand interactions. Difopein (TFA) leads to induction of apoptosis and enhances the ability of cisplatin to kill cells. price>
R-OR-585 Acrylamide-Ferrocene Acrylamide(AA)-Ferrocene from ruixi.Acrylamide is a colorless and transparent sheet crystal, containing double bond and amide group, with the chemical continuity of double bond.Ferrocene is an organic transition metal compound with aromatic properties. Ferrocene, also known as dicyclopentadiene iron and cyclopentadienyl iron, is an organic metal compound with the formula of Fe (C5H5) 2. price>
R-WY203 ACA-PEG-N3 ACA-PEG-N3 ,acrylamide-Polyethylene glycol-azide from ruixi. Acrylamide peg azide (N3) is a heterobifunctional peg reagent. Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. price>
R-R-1605 Cucurbitacin B CAS No.6199-67-3 Cucurbitacin B/CAS No.6199-67-3 belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest, but induces cell apoptosis. Cucurbitacin B has potent anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective activity. price>
R-OD-001 DOTA-Dextran DOTA-Dextran from ruixi.Dextran is a homopolysaccharide composed of glucose as monosaccharide, and the glucose units are connected by glycosidic bond. Dextran is one of the bacterial polysaccharides, also known as dextran. price>