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R-R-1652 Aspidin BB CAS No.584-28-1 Aspidin BB/CAS No.584-28-1 is a phloroglucinol derivative, which can be isolated from the aerial part of Dryopteris championii. Aspidin BB has anticancer activity. Aspidin BB induces cell cycle arrest and apoptosis in human ovarian HO-8910 cells. price>
R-M-289 H-Leu-Gly-OH,CAS: 686-50-0 The dipeptide Leu-Gly inhibits the ubiquitin-mediated proteolysis.Leu-Gly is a dipeptide formed from L-leucine and glycine residues. It has a role as a metabolite. It is a tautomer of a Leu-Gly zwitterion. price>
R-R-1653 Brazilin CAS No.474-07-7 Brazilin/CAS No.474-07-7 is a red dye precursor obtained from the heartwood of several species of tropical hardwoods. Brazilin inhibits the cells proliferation, promotes apoptosis, and induces autophagy through the AMPK/mTOR pathway. Brazilin shows chondroprotective and anti-inflammatory activities. price>
R-M-291 3X Flag Peptide trifluoroacetate salt 3X FLAG peptide TFA(CAS :402750-12-3) is a synthetic peptide with a 3-time repeated DYKXXD motif. price>
R-R-1654 nor-NOHA acetate CAS No.1140844-63-8 nor-NOHA acetate (Nω-Hydroxy-nor-L-arginine acetate)/CAS No.1140844-63-8 is a specific and reversible arginase inhibitor, induces apoptosis in ARG2-expressing cells under hypoxia but not normoxia. Anti-leukemic activity, effective in endothelial dysfunction, immunosuppression and metabolism. price>
R-M-292 Glycyl-L-valine A good substrate for dipeptide hydrolase activities in rat intestinal mucosa.Glycyl-L-valine is a dipeptide that contains glycine and valine. price>
R-R-1655 Prostaglandin A2 CAS No.13345-50-1 Prostaglandin A2 (PGA2)/CAS No.13345-50-1, a human endogenous metabolite of PGE2, is an antitumor agent. Prostaglandin A2 induces p53-dependent apoptosis. Prostaglandin A2 also has antiviral activity. price>
R-M-293 Ac-Arg-Gly-Lys-AMC trifluoroacetate salt Ac-Arg-Gly-Lys-AMC trifluoroacetate salt(CAS :660846-99-1)from ruixi.Control for the two step histone deacetylase assay with Ac-Arg-Gly-Lys(Ac)-AMC. Ac-RGK-AMC corresponds to the product of the deacetylase reaction, which is subsequently cleaved by trypsin. price>
R-R-1656 4-Bromo A23187 CAS No.76455-48-6 4-Bromo A23187/CAS No.76455-48-6 is a halogenated analog of the highly selective calcium ionophore A-23187. 4-Bromo A23187, a calcium modulator, induces apoptosis in different cells, including HL-60 cells. price>
R-M-500 Ac-Arg-Gly-Lys(Ac)-AMC trifluoroacetate salt Ac-RGK(Ac)-AMC(CAS :660846-97-9),fluorogenic substrate for assaying histone deacetylase (HDAC) activity in a two-step enzymatic reaction. The assay consists of the initial lysine deacetylation by HDAC followed by the release of the fluorescent group by trypsin. price>
R-R-1657 Azadirachtin CAS No.11141-17-6 Azadirachtin/CAS No.11141-17-6, one of the most promising botanical insecticides, is widely used for pest control. Azadirachtin induces apoptosis in insect cell lines, including Sf9, SL-1 and BTI-Tn-5B1-4. price>
R-M-501 Ac-Arg-Leu-Arg-AMC trifluoroacetate salt Ac-RLR-AMC(CAS :929903-87-7),fluorogenic substrate for assaying the trypsin-like activity of purified proteasomes (Km = 78 μM). price>
R-R-1658 Chaetoglobosin A CAS No.50335-03-0 Chaetoglobosin A/CAS No.50335-03-0, the active principle within the extract of Penicillium aquamarinium, is a member of the cytochalasan family. Chaetoglobosin A preferentially induces apoptosis. Chaetoglobosin A targets filamentous actin in CLL cells and thereby induces cell-cycle arrest and inhibits membrane ruffling and cell migration. price>
R-M-502 Ac-Arg-Ser-Leu-Lys-AMC trifluoroacetate salt Ac-RSLK-AMC(CAS : 259176-76-6),a fluorogenic substrate for Site-1 protease (S1P), a mammalian subtilisin-related serine protease that cleaves sterol regulatory element-binding proteins (SREBPs).The peptide sequence RSLK corresponds to the internal propeptide cleavage site that generates active S1P. price>
R-R-1659 Casein Kinase inhibitor A51 CAS No.2079068-74-7 Casein Kinase inhibitor A51/CAS No.2079068-74-7 is a potent and orally active casein kinase 1α (CK1α) inhibitor. Casein Kinase inhibitor A51 induces leukemia cell apoptosis, and has potent anti-leukemic activities. price>
R-M-503 Ac-Asp-Arg-Leu-Asp-Ser-OH Ac-Asp-Arg-Leu-Asp-Ser-OH(CAS:153959-57-0),Ac-DRLDS from ruixi.The acetylated pentapeptide Ac-DRLDS inhibits tumor cell adhesion to laminin, fibronectin, vitronectin, and RGDS-IgG substrates. Ac-DRLDS also inhibits tumor cell adhesion to CS-1-IgG as well as the CS-1-derived peptide (EILDV), in a concentration-dependent manner. Although the inhibitory effect was less than that of EILDV, this peptide retains the properties of both RGDS and EILDV. price>
R-R-1660 Patulin CAS No.149-29-1 Patulin (Terinin)/CAS No.149-29-1 is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, is suspected to be clastogenic, mutagenic, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage. price>
R-M-504 Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-OH Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-OH,CAS : 66641-26-7 from ruixi.Renin cleavage of Ac-DRVYIHPFHLLVYS yields N-terminally acetylated angiotensin I and LVYS. price>
R-R-1661 (Rac)-Hesperetin-d3 CAS No.1346605-26-2 (Rac)-Hesperetin-d3/CAS No.1346605-26-2 is the deuterium labeled (Rac)-Hesperetin. (Rac)-Hesperetin is the racemate of Hesperetin. Hesperetin is a natural flavanone, and acts as a potent and broad-spectrum inhibitor against human UGT activity. Hesperetin induces apoptosis via p38 MAPK activation. price>
R-M-505 NAAG NAAG,N-Acetyl-L-aspartyl-L-glutamic acid(CAS :3106-85-2) from ruixi.An endogenous dipeptide with high affinity for a brain glutamate receptor. NAAG is the most abundant peptide neurotransmitter in the mammalian central nervous system. price>