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Catalog	name	Description	price
R-M-471	Abz-Ala-Phe-Ala-Phe-Asp-Val-Phe-3-nitro-Tyr-Asp-OH trifluoroacetate salt	Abz-AFAFDVY(NO₂)D,a fluorogenic (FRET) substrate for endoproteinase AspN,Asp-specific proteases from Staphylococcus aureus,Bacillus licheniformis and Streptomyces griseus.	price>
R-M-689	Endomorphin-1 trifluoroacetate salt	Endomorphin-1 trifluoroacetate salt,CAS :189388-22-5 from ruixi.Endomorphin-1 (YPWF-amide) is the most potent and selective endogenous agonist for the mu-opiate receptor so far described .It may be a natural ligand for this receptor.Endomorphin-1 has been shown to inhibit the aggregation of Aβ in vitro and is effective in vivo.	price>
R-R-1842	Ursonic acid CAS No.6246-46-4	Ursolic acid/CAS No.6246-46-4, a naturally occurring triterpenoid, induces the apoptosis of human cancer cells through multiple signaling pathways.	price>
R-CG-021	DSPE-Se-Se-PEG-sh	1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Se-Se-(polyethylene glycol)-thiol,DSPE-Se-Se-PEG-sh from ruixi.The diselenium bond(se-se) is a new type of GSH responsive covalent chemical bond. DSPE is linked to the double selenium bond then coupling PEG thiol(peg-sh).The product(DSPE-Se-Se-PEG-thiol)with GSH responsive double selenium micelles was prepared.By using the double selenium bond material, the drug can be released from the carrier rapidly in the environment of high GSH, so it can be used in drug delivery system (DDS).	price>
R-M-472	Abz-Ala-Phe-Arg-Phe-Ser-Gln-EDDnp trifluoroacetate salt	Abz-AFRFSQ-EDDnp, best human kallikrein 6 (hK6) FRET substrate so far described.	price>
R-M-690	Endomorphin-2 trifluoroacetate salt	Endomorphin-2 trifluoroacetate salt ,CAS: 141801-26-5 from ruixi.Endomorphin-2 (YPFF-amide) shows, as endomorphin-1, the highest affinity and specificity for the mu-opiate receptor found so far in the mammalian nervous system. It has potent mu-selective bioactivity, including analgesia. Szegedi et al. showed that endomorphin-2 protects against Aβ 1-42 in vitro and in vivo. Acylated endomorphin-2 is used as cosmetic ingredient for sensitive skin care.	price>
R-R-1843	Trametinib-13C,d3 CAS No.2712126-59-3	Trametinib-13C,d3/CAS No.2712126-59-3 is the 13C- and deuterium labeled Trametinib. Trametinib (GSK1120212; JTP-74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib activates autophagy and induces apoptosis.	price>
R-CG-022	DSPE-Se-Se-PEG-N3	1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Se-Se-(polyethylene glycol)-Azide,DSPE-Se-Se-PEG-N3 from ruixi.The diselenium bond(se-se) is a new type of GSH responsive covalent chemical bond. DSPE is linked to the double selenium bond then coupling PEG thiol(peg-N3).The product(DSPE-Se-Se-PEG-N3)with GSH responsive double selenium micelles was prepared.By using the double selenium bond material, the drug can be released from the carrier rapidly in the environment of high GSH, so it can be used in drug delivery system (DDS).	price>
R-M-473	Abz-Arg-Val-Lys-Arg-Gly-Leu-Ala-m-nitro-Tyr-Asp-OH trifluoroacetate salt	Internally quenched fluorogenic peptide substrate containing anthranilic acid as fluorescent donor and m-nitro-tyrosine as acceptor (quencher).The sequence Abz-RVKRGLAY(NO₂)E is based on the sequence of hemagglutinin.The FRET substrate is efficiently cleaved by furin, a subtilisin-like eukaryotic serine endoprotease.Its kcat/Km value is over 2000-fold higher than that of the commonly used substrate Boc-Arg-Val-Arg-Arg-AMC (I-1645).FRET Substrate for the basic residue-specific yeast aspartyl protease yapsin 1.	price>
R-M-691	β-Endorphin (30-31) (human)	β-Endorphin (30-31) (human),CAS: 7412-78-4 from ruixi.The C-terminal dipeptide Gly-Glu was shown to be an effective neurotrophic factor for the maintenance of acetylcholinesterase at both superior cervical ganglia in the denervated cat. Moreover,β-endorphin can bind to serum glycoproteins at sites for which glycyl-L-glutamic acid competes. A potential impurity of glycyl-L-glutamine used as source for L-glutamine.	price>
R-R-1844	PARP14 inhibitor H10 CAS No.2084811-68-5	PARP14 inhibitor H10/CAS No.2084811-68-5, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (≈24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis.	price>
R-M-474	Abz-Asp-Asp-Ile-Val-Pro-Cys-Ser-Met-Ser-3-nitro-Tyr-Thr-NH₂	The internally quenched (FRET) substrate Abz-DDIVPCSMSY(NO₂)T-NH₂allows the direct, specific detection of NS3-4A protease activity .	price>
R-M-692	γ-Endorphin	γ-Endorphin,CAS :60893-02-9 from ruixi.It can be applied to Opioid Research.	price>
R-R-1845	Eftozanermin alfa CAS No.1820660-69-2	Eftozanermin alfa (ABBV-621)/CAS No.1820660-69-2 is a second-generation tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) agonist. Eftozanermin alfa induces apoptosis in tumor cells by activation of death receptors 4/5. Eftozanermin alfa can be used for the research of multiple solid and heme malignancies.	price>
R-CG-023	DSPE-Se-Se-PEG-alkyne	1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Se-Se-(polyethylene glycol)-alkyne,DSPE-Se-Se-PEG-N3 from ruixi.The diselenium bond(se-se) is a new type of GSH responsive covalent chemical bond. DSPE is linked to the double selenium bond then coupling PEG thiol(peg-alkyne).The product(DSPE-Se-Se-PEG-alkyne)with GSH responsive double selenium micelles was prepared.By using the double selenium bond material, the drug can be released from the carrier rapidly in the environment of high GSH, so it can be used in drug delivery system (DDS).	price>
R-M-475	Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH,CAS:827044-38-2	Abz-GIVRAK(Dnp), a very efficient and selective FRET substrate for human cathepsin B.	price>
R-M-693	Endothelin-1 (human, bovine, dog, mouse, porcine, rat) acetate salt	Endothelin-1 (human, bovine, dog, mouse, porcine, rat) acetate salt,CAS: 117399-94-7 from ruixi.Endothelin-1, a 21-amino acid peptide from vascular endothelial cells of different mammalian species, is one of the most potent vasoconstrictors. ET-1 exerts a wide variety of effects on both vascular and non-vascular (e.g. heart, lung, brain) tissues. Toxic peptides from a snake venom, the sarafotoxins, show structural and functional homology to ET-1. The role of ET-1 in clinical hypertension has been reviewed by Dhaun et al. and by Sreenivas and Oparil. ET-1 plays a central role in lung fibrosis.	price>
R-R-1846	Puromycin aminonucleoside CAS No.58-60-6	Puromycin aminonucleoside (NSC 3056)/CAS No.58-60-6 is the aminonucleoside portion of the antibiotic puromycin, and used in nephrosis animal models. Puromycin aminonucleoside induces apoptosis. Puromycin aminonucleoside is a reversible inhibitor of dipeptidyl peptidase II and cytosol alanyl aminopeptidase. Puromycin aminonucleoside induces secretion of cell migrasome.	price>
R-CG-024	DSPE-Se-Se-PEG-CHO	1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Se-Se-(polyethylene glycol)-CHO ,DSPE-Se-Se-PEG-N3 from ruixi.The diselenium bond(se-se) is a new type of GSH responsive covalent chemical bond. DSPE is linked to the double selenium bond then coupling PEG thiol(peg-CHO).The product(DSPE-Se-Se-PEG-CHO)with GSH responsive double selenium micelles was prepared.By using the double selenium bond material, the drug can be released from the carrier rapidly in the environment of high GSH, so it can be used in drug delivery system (DDS).	price>
R-M-476	Abz-Gly-p-nitro-Phe-Pro-OH trifluoroacetate salt	Fluorogenic (FRET) substrate for angiotensin I-converting enzyme (ACE). Enzymatic cleavage of Abz-Gly-Nph-Pro yields Abz-Gly-OH emitting at 420 nm.	price>

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