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Catalog	name	Description	price
R-R-1919	Phthalazinone pyrazole CAS No.880487-62-7	Phthalazinone pyrazole/CAS No.880487-62-7 is a potent, selective, and orally active inhibitor of Aurora-A kinase with an IC50 of 0.031 μM. Phthalazinone pyrazole can arrests mitosis and subsequently inhibit tumor growth via apoptosis of proliferating cells. Phthalazinone pyrazole suppresses the epithelial-mesenchymal transition (EMT) during the differentiation of hepatocyte-like cells (HLCs) from human embryonic stem cells.	price>
R-CG-087	PCL-Hydrazone(hyd)-peg-Biotin	Poly(ε-caprolactone)-Hydrazone(hyd)- poly(ethylene glycol)-BIOTIN,PCL-Hydrazone(hyd)-peg-Biotin from ruixi.Hydrazone bond has pH response effect. PCL was linked to hydrazone bond and PEG Biotin was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells.	price>
R-M-771	Cecropin P1 trifluoroacetate salt	Cecropin P1 (SWLSKTAKKLENSAKKRISEGIAIAIQGGPR), a homolog of insect cecropins isolated from pig intestine, was thought to be the first mammalian antimicrobial peptide. Later studies showed that the peptide is produced by the intestinal parasitic nematode Ascaris suum. The 31 amino acid peptide is highly potent against Gram-negative bacteria but has a reduced activity against Gram-positive bacteria. A disruptive effect on bacterial membranes has been proposed as mechanism of antimicrobial activity.	price>
R-R-1920	Lometrexol CAS No.106400-81-1	Lometrexol (DDATHF)/CAS No.106400-81-1, an antipurine antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol can further inhibit de novo purine synthesis, causing abnormal cell proliferation and apoptosis, even cell cycle arrest. Lometrexol has anticancer activity. Lometrexol also is a potent human Serine hydroxymethyltransferase1/2 (hSHMT1/2) inhibitor.	price>
R-CG-088	PCL-Hydrazone(hyd)-peg-Thiol(sh)	Poly(ε-caprolactone)-Hydrazone(hyd)- poly(ethylene glycol)-Thiol,PCL-Hydrazone(hyd)-peg-sh from ruixi.Hydrazone bond has pH response effect. PCL was linked to hydrazone bond and PEG thiol was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells.	price>
R-M-772	Cecropin B (free acid) trifluoroacetate salt	Cecropin B (free acid) trifluoroacetate salt ,CAS:203265-23-0 from ruixi.It can be used Antimicrobial & Antiviral Peptides.	price>
R-R-1921	Lometrexol hydrate CAS No.1435784-14-7	Lometrexol (DDATHF) hydrate/CAS No.1435784-14-7, an antipurine antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol hydrate can further inhibit de novo purine synthesis, causing abnormal cell proliferation and apoptosis, even cell cycle arrest. Lometrexol hydrate has anticancer activity. Lometrexol hydrate also is a potent human Serine hydroxymethyltransferase1/2 (hSHMT1/2) inhibitor.	price>
R-CG-089	PCL-Hydrazone(hyd)-peg-Azide(N3)	Poly(ε-caprolactone)-Hydrazone(hyd)- poly(ethylene glycol)-Thiol,PCL-Hydrazone(hyd)-peg-sh from ruixi.Hydrazone bond has pH response effect. PCL was linked to hydrazone bond and PEG thiol was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells.	price>
R-M-773	Amyloid β-Protein (1-39) trifluoroacetate salt	Amyloid β-Protein (1-39) trifluoroacetate salt,CAS:115427-62-8 from ruixi.It can be used Alzheimer Disease.	price>
R-R-1922	Pinoresinol CAS No.487-36-5	Pinoresinol/CAS No.487-36-5 is a lignol of plant origin serving for defense in a caterpillar. Pinoresinol drastically sensitizes cancer cells against TNF-related apoptosis-inducing ligand (TRAIL) -induced apoptosis.	price>
R-CG-090	PCL-Hydrazone(hyd)-peg-Alkyne	Poly(ε-caprolactone)-Hydrazone(hyd)- poly(ethylene glycol)-Alkyne,PCL-Hydrazone(hyd)-peg-Alkyne from ruixi.Hydrazone bond has pH response effect. PCL was linked to hydrazone bond and PEG Alkyne was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells.	price>
R-M-774	Granuliberin-R trifluoroacetate salt	Granuliberin-R is a mast cell degranulating peptide, originally isolated from the skin of the frog Rana rugosa.	price>
R-R-1923	EGFR T790M/L858R-IN-2	EGFRT790M/L858R-IN-2 is a potent and selective EGFRT790M/L858R inhibitor with IC50 values of 3.5, 1290 nM for EGFRT790M/L858R, EGFR WT, respectively. EGFRT790M/L858R-IN-2 decreases the expression of p-EGFR, P-AKT, P-ERK1/2. EGFRT790M/L858R-IN-2 induces Apoptosis and cell cycle arrest in the G1 phase. EGFRT790M/L858R-IN-2 shows anti-cancer activity.	price>
R-CG-091	PCL-Hydrazone(hyd)-peg-folate(FA)	Poly(ε-caprolactone)-Hydrazone(hyd)- poly(ethylene glycol)-folate,PCL-Hydrazone(hyd)-peg-folate from ruixi.Hydrazone bond has pH response effect. PCL was linked to hydrazone bond and PEG folate was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells.	price>
R-M-775	GRF (1-29) amide (human) acetate salt	GRF (1-29) amide (sermorelin) is the shortest GRF fragment with full biological activity.	price>
R-R-1924	Peimisine CAS No.19773-24-1	Peimisine (Ebeiensine)/CAS No.19773-24-1 is a muscarinic M receptor antagonist and angiotensin converting enzyme (ACE) inhibitor. Peimisine shows anti-tumor, anti-inflammatory, antihypertensive activities. Peimisine can induce apoptosis and be used in cough and asthma research.	price>
R-CG-092	PCL-Hydrazone(hyd)-peg-OH	Poly(ε-caprolactone)-Hydrazone(hyd)- poly(ethylene glycol)-hydroxyl ,PCL-Hydrazone(hyd)-peg-OH from ruixi.Hydrazone bond has pH response effect. PCL was linked to hydrazone bond and PEG-hydroxyl was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells.	price>
R-M-776	GRF (1-29) amide (rat)	It is a synthetic peptide, only used for scientific research, not for human body.	price>
R-R-1925	Dalotuzumab CAS No.1005389-60-5	Dalotuzumab (MK-0646)/CAS No.1005389-60-5 is a recombinant humanized monoclonal antibody (IgG1 type) targeting IGF-1R. Dalotuzumab acts by inhibiting IGF-1- and IGF-2-mediated tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation. Dalotuzumab also induces apoptosis and cycle arrest. Dalotuzumab in combination with other anticancer agents such as statins can enhance the antitumor activity of Dalotuzumab in vitro and in vivo.	price>
R-CG-093	PCL-Hydrazone(hyd)-peg-CHO	Poly(ε-caprolactone)-Hydrazone(hyd)- poly(ethylene glycol)-CHO,PCL-Hydrazone(hyd)-peg-CHO from ruixi.Hydrazone bond has pH response effect. PCL was linked to hydrazone bond and PEG-CHO was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure, the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells.	price>

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