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R-CG-119 Lactoferrin(LF)-PEG-Alkyne Lactoferrin-poly(ethylene glycol)-Alkyne,Lactoferrin(LF)-PEG-Alkyne,Alkyne-peg-LF from ruxii.Lactoferrin (LF) is an important non heme iron binding glycoprotein in milk. It is a monomer glycoprotein with bactericidal activity in neutrophils.Lactoferrin is not only involved in the transport of iron, but also has powerful biological functions such as broad-spectrum antibacterial, antioxidant, anticancer, regulating immune system, etc. it is considered as a new antibacterial, anticancer drug and a food and feed additive with great development potential. price>
R-M-804 Cortistatin-17 (human) trifluoroacetate salt Cortistatin-17 shows structural similarities to somatostatin. The peptide binds to all somatostatin receptor subtypes (SSTR) in a similar way as the rat cortistatin. Its inhibitory effects on forskolin-stimulated cAMP production in chinese hamster ovary cells expressing SSTR2-5 are dose dependent but slightly less efficient than that of somatostatin-14. price>
R-R-1953 ULK1-IN-2 CAS No.2497409-01-3 ULK1-IN-2 (compound 3s) is a potent ULK1 inhibitor. ULK1-IN-2 shows highest cytotoxic effect against cancer cell lines, with IC50 of 1.94 μM in A549. ULK1-IN-2 can induce apoptosis and simultaneously block autophagy, and can be used to study NSCLC (Non-small cell lung cancer). price>
R-CG-120 mPEG-thioketal(TK)-NH2 methoxy polyethylene glycol-thioketal(TK)-Amine,mPEG-thioketal(TK)-NH2,Amine-thioketal(TK)-mpeg,mpeg-thioketal(TK)-Amino from ruixi.thioketal(TK) has the characteristics of active oxygen reaction.In ROS environment, the chemical bond of keto mercaptan breaks, forming ketone and mercaptan, realizing drug release. As the final product, mPEG-thioketal(TK)-NH2 has ROS response characteristics, so as to realize the drug delivery system. price>
R-M-805 Cortistatin-29 (human) trifluoroacetate salt Cortistatin-29 (human) (CST (human)) represents an antiinflammatory, immunomodulatory factor with a potential multistep therapeutic use in the treatment of septic shock and Crohn disease. price>
R-R-1954 Darapladib CAS No.356057-34-6 Darapladib (SB-480848)/CAS No.356057-34-6 is an orally active, selective and reversible Lp-PLA2 inhibitor (IC50=0.25 nM). Darapladib can trigger irreversible actions on glioma cell apoptosis and induce cycle arrest. Darapladib can be used in the study of atherosclerosis and cancer. price>
R-CG-121 mPEG-thioketal(TK)-Mal methoxy polyethylene glycol-thioketal(TK)-Maleimide,mPEG-thioketal(TK)-Mal,Mal-tk-mpeg from ruixi.thioketal(TK) has the characteristics of active oxygen reaction.In ROS environment, the chemical bond of keto mercaptan breaks, forming ketone and mercaptan, realizing drug release. As the final product, mPEG-thioketal(TK)-NH2 has ROS response characteristics, so as to realize the drug delivery system. price>
R-M-806 CRAMP (mouse) trifluoroacetate salt,CAS : 376364-36-2 CRAMP is a cathelin-related antimicrobial peptide expressed in the embryonic and adult mouse. Functional studies showed CRAMP to be a potent antibiotic against Gram-negative bacteria by inhibiting growth of a variety of bacterial strains and by permeabilizing the inner membrane of E.coli directly. price>
R-R-1955 Bcl-xL antagonist 2 CAS No.1235032-75-3 Bcl-xL antagonist 2/CAS No.1235032-75-3 is a potent, selective, and orally active antagonist of BCL-XL with an IC50 and Ki of 0.091 μM and 65 nM, respectively. Bcl-xL antagonist 2 promotes the apoptosis of cancer cells. Bcl-xL antagonist 2 has the potential for the research of the chronic lymphocytic leukemia (CLL) and non-Hodgkin’s lymphoma (NHL). price>
R-CG-122 mPEG-thioketal(TK)-NHS methoxy polyethylene glycol-thioketal(TK)-N-hydroxylsuccinimide,mPEG-thioketal(TK)-NHS,NHS-tk-mpeg from ruixi.thioketal(TK) has the characteristics of active oxygen reaction.In ROS environment, the chemical bond of keto mercaptan breaks, forming ketone and mercaptan, realizing drug release. As the final product, mPEG-thioketal(TK)-NH2 has ROS response characteristics, so as to realize the drug delivery system. price>
R-M-807 CRAMP-18 (mouse) trifluoroacetate salt CRAMP-18 (mouse) corresponds to the functional region of the antibacterial peptide CRAMP. It displayed potent antibacterial activity against several bacteria with no hemolytic activity (minimal inhibitory concentration: 12.5-50 µM). price>
R-R-1956 Loncastuximab tesirine CAS No.1879918-31-6 Loncastuximab tesirine/CAS No.1879918-31-6 is a human cluster of differentiation 19 (CD19)-directed antibody-drug conjugate (ADC). Once bound to CD19 on the cell membrane, loncastuximab tesirine is rapidly internalised and triggers cell death. Loncastuximab tesirin induces cell apoptosis, it can be used for the research of diffuse large B-cell lymphoma. price>
R-CG-123 mPEG-thioketal(TK)-biotin methoxy polyethylene glycol-thioketal(TK)-biotin,mPEG-thioketal(TK)-biotin,biotin-tk-mpeg from ruixi.thioketal(TK) has the characteristics of active oxygen reaction.In ROS environment, the chemical bond of keto mercaptan breaks, forming ketone and mercaptan, realizing drug release. As the final product, mPEG-thioketal(TK)-NH2 has ROS response characteristics, so as to realize the drug delivery system. price>
R-M-818 CRF (bovine) trifluoroacetate salt,CAS : 92307-52-3 CRF (bovine) trifluoroacetate salt,CAS : 92307-52-3 from ruixi.It can be applied to pituitary & hypothalamic hormones. price>
R-R-1957 SB-218078 CAS No.135897-06-2 SB-218078/CAS No.135897-06-2 is a potent, selective, ATP-competitive and cell-permeable checkpoint kinase 1 (Chk1) inhibitor that inhibits Chk1 phosphorylation of cdc25C with an IC50 of 15 nM. SB-218078 is less potently inhibits Cdc2 (IC50 of 250 nM) and PKC (IC50 of 1000 nM). SB-218078 causes apoptosis by DNA damage and cell cycle arrest. price>
R-CG-124 mPEG-thioketal(TK)-sh methoxy polyethylene glycol-thioketal(TK)-thiol,mPEG-thioketal(TK)-sh,Hs-tk-mpeg from ruixi.thioketal(TK) has the characteristics of active oxygen reaction. In ROS environment, the chemical bond of keto mercaptan breaks, forming ketone and mercaptan, realizing drug release. As the final product, mPEG-thioketal(TK)-NH2 has ROS response characteristics, so as to realize the drug delivery system. price>
R-M-808 CRF (human, rat) acetate salt CRF (corticotropin-releasing factor) is a 41-peptide produced mainly in the hypothalamus. The peptide hormone stimulates ACTH release from the anterior lobe of the pituitary gland. CRH plays an important role in the endocrine, behavioral, and immune response to stress and probably as well in the regulation of energy balance. price>
R-R-1958 Periplocin CAS No.13137-64-9 Periplocin/CAS No.13137-64-9 is a cardiotonic steroid isolated from root-bark Periploca sepium Bunge. Periplocin promotes tumor cell apoptosis and inhibits tumor growth. Periplocin has the potential to facilitate wound healing through the activation of Src/ERK and PI3K/Akt pathways mediated by Na/K-ATPase. price>
R-CG-125 mPEG-thioketal(TK)-N3 methoxy polyethylene glycol-thioketal(TK)-Azide,mPEG-thioketal(TK)-N3,Azide-thioketal(TK)-mpeg from ruixi.thioketal(TK) has the characteristics of active oxygen reaction.In ROS environment, the chemical bond of keto mercaptan breaks, forming ketone and mercaptan, realizing drug release. As the final product, mPEG-thioketal(TK)-NH2 has ROS response characteristics, so as to realize the drug delivery system. price>
R-M-809 Biotinyl-CRF (human, rat),CAS : 105883-79-2 Biotinyl-CRF (human, rat),CAS : 105883-79-2 from ruixi. It is a kind of biotinylated peptides, which can be applied to pituitary & hypothalic hormones. price>