Home > Keywords >
Catalog | name | Description | price |
---|---|---|---|
R-R-1959 | AS-99 TFA | AS-99 TFA is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 µM, Kd= 0.89 µM) with anti-leukemic activity. AS-99 TFA blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo. | price> |
R-CG-126 | mPEG-thioketal(TK)-Alkyne | methoxy polyethylene glycol-thioketal(TK)-Alkyne,mPEG-thioketal(TK)-Alkyne from ruixi.thioketal(TK) has the characteristics of active oxygen reaction. In ROS environment, the chemical bond of keto mercaptan breaks, forming ketone and mercaptan, realizing drug release. As the final product, mPEG-thioketal(TK)-NH2 has ROS response characteristics, so as to realize the drug delivery system. | price> |
R-M-810 | Tyr-CRF (human, rat),CAS : 100513-58-4 | Tyr-CRF (human, rat),CAS :100513-58-4 from ruixi.It can be applied to pituitary & hypothalamic hormones.It can only be used for scientific research, not for human body. | price> |
R-R-1960 | ADH-6 TFA | ADH-6 TFA is a tripyridylamide compound. The self-assembly of the aggregated nucleonic domain of the mutant p53 DBD was abolished by ADH-6. ADH-6 TFA targets and dissociates mutant p53 aggregates in human cancer cells, thereby restoring p53 transcriptional activity, leading to cell cycle arrest and apoptosis. ADH-6 TFA has the potential to study cancer diseases. | price> |
R-MP-001 | mpeg-pALD(propionaldehyde) | mpeg-pALD(propionaldehyde),mPEG-aldehyde,mPEG-ALD,Methoxy-PEG-Propionaldehyde,mPEG-Propionaldehyde,Methoxypoly(ethylene glycol)-propionaldehyde from ruixi.mPEG-aldehyde (propionaldehyde) reacts with amine and N-terminal of peptide and protein to form an imine containing a C=N double bond, which can be further reduced. PEG aldehyde or ketone derivatives can be used in reversible PEGylation through its reaction with hydrazine or hydrazide forming a hydrolytic acyl hydrozone linkage. | price> |
R-M-811 | CCAP | Native and synthetic CCAP displayed high ino- and chronotropic effects on a semi-isolated crab heart preparation. | price> |
R-R-1961 | Astaxanthin CAS No.472-61-7 | Astaxanthin/CAS No.472-61-7, the red dietary carotenoid, is an orally effective and potent antioxidant. Astaxanthin inhibits NF-κB and down-regulates VEGF in blood glucose. Astaxanthin exerts anti-cancer cell proliferation, increases apoptosis, impairs migration and invasion by activating PPARγ and reducing the expression of STAT3. Astaxanthin also has neuroprotective and anti-inflammatory activity and can be used in studies of cancer, diabetic retinopathy, cardiovascular disease, and in the coloring of animal feed. | price> |
R-CG-127 | Glycyrrhetinic acid(GA)-peg-cooh | Glycyrrhetinic acid(GA)-peg-cooh,Glycyrrhetinic acid-polyethylene glycol-carboxy,GA-PEG-COOH,Glycyrrhetinic acid(GA)-peg-carboxylic acid from ruixi.The main functional components of Glycyrrhiza are glycyrrhizic acid. The molecular structure of glycyrrhizic acid contains 1 molecule glycyrrhetinic acid and 2 molecule glucuronic acid. Glycyrrhetinic acid has anti-inflammatory, anti-oxidation, anti-tumor, antibacterial, anti-virus and other functions. | price> |
R-M-812 | (H-Cys-Gly-OH)₂(Disulfide bond),CAS: 7729-20-6 | (H-Cys-Gly-OH)₂(Disulfide bond),Besides its reduced form, this product of glutathione metabolism is found in plasma. | price> |
R-R-1962 | A-192621 CAS No.195529-54-5 | A-192621/CAS No.195529-54-5 is a potent, nonpeptide, orally active and selective endothelin B (ETB) receptor antagonist with an IC50 of 4.5 nM and a Ki of 8.8 nM. The selectivity of A-192621 is 636-fold higher than ETA (IC50 of 4280 nM and Ki of 5600 nM). A-192621 promotes apoptosis in PASMCs. A-192621 alos causes elevation of arterial blood pressure and an elevation in the plasma ET-1 level. | price> |
R-CG-128 | Glycyrrhetinic acid(GA)-peg-NH2 | Glycyrrhetinic acid(GA)-peg-NH2,Glycyrrhetinic acid-polyethylene glycol-Amine,GA-PEG-NH2 from ruixi.The main functional components of Glycyrrhiza are glycyrrhizic acid. The molecular structure of glycyrrhizic acid contains 1 molecule glycyrrhetinic acid and 2 molecule glucuronic acid. Glycyrrhetinic acid has anti-inflammatory, anti-oxidation, anti-tumor, antibacterial, anti-virus and other functions. | price> |
R-M-813 | (H-Cys-Tyr-OH)₂(Disulfide bond) | (H-Cys-Tyr-OH)₂(Disulfide bond),CAS: 7369-94-0 from ruixi. It can be used for Di- and Tripeptides. | price> |
R-R-1963 | Thienopyridone CAS No.1018454-97-1 | Thienopyridone/CAS No.1018454-97-1 is a potent and selective phosphatase of regenerating liver (PRL) phosphatase inhibitor with IC50s of 173 nM, 277 nM and 128 nM for PRL-1, PRL-2, and PRL-3, respectively. Thienopyridone shows minimal effects on other phosphatases. Thienopyridone induces p130Cas cleavage and apoptosis and has anticancer effects. | price> |
R-CG-129 | Glycyrrhetinic acid(GA)-peg-mal | Glycyrrhetinic acid(GA)-peg-mal,Glycyrrhetinic acid-polyethylene glycol-Maleimide ,GA-PEG-mal from ruixi.The main functional components of Glycyrrhiza are glycyrrhizic acid. The molecular structure of glycyrrhizic acid contains 1 molecule glycyrrhetinic acid and 2 molecule glucuronic acid. Glycyrrhetinic acid has anti-inflammatory, anti-oxidation, anti-tumor, antibacterial, anti-virus and other functions. | price> |
R-M-711 | Bradykinin acetate salt | Bradykinin acetate salt,CAS :6846-03-3 from ruixi.The pharmacological properties of bradykinin include smooth muscle contraction, vasodilation and hypotension. Bradykinin increases capillary permeability together with edema formation and induction of pain. Bradykinin induces bronchoconstriction in asthmatic subjects and symptoms of rhinitis in nasal provocation. | price> |
R-M-814 | (H-Cys-Val-OH)₂(Disulfide bond),CAS :21141-84-4 | (H-Cys-Val-OH)₂(Disulfide bond),CAS :21141-84-4 from ruixi. It can be used for Di- and Tripeptides. | price> |
R-R-1964 | NSC348884 CAS No.81624-55-7 | NSC348884/CAS No.81624-55-7 is a nucleophosmin (NPM) inhibitor, it disrupts oligomer formation and induces apoptosis, inhibits cell proliferation with IC50s of 1.7-4.0 μM in distinct cancer cell lines. NSC348884 can be used for the research of cancer. | price> |
R-CG-130 | Glycyrrhetinic acid(GA)-peg-nhs | Glycyrrhetinic acid(GA)-peg-nhs,Glycyrrhetinic acid-polyethylene glycol-N-hydroxylsuccinimide ,GA-PEG-nhs from ruixi.The main functional components of Glycyrrhiza are glycyrrhizic acid. The molecular structure of glycyrrhizic acid contains 1 molecule glycyrrhetinic acid and 2 molecule glucuronic acid. Glycyrrhetinic acid has anti-inflammatory, anti-oxidation, anti-tumor, antibacterial, anti-virus and other functions. | price> |
R-M-815 | H-Cys-psi(CH₂NH)Val-psi(CH₂NH)Phe-Met-OH trifluoroacetate salt | B581, Cys-psi(CH₂NH)-Val- psi[CH₂NH]-Phe-Met is a farnesyltransferase (FTase) inhibitor of special stability and membrane permeability. Due to its high selectivity, B581 is more than 30-fold more active against FTase (IC₅₀= 21 nM in vitro) than against geranylgeranyltransferase (GGTase). Inhibitors of the farnesyltransferase are potential candidates for the development of anticancer drugs. | price> |
R-R-1965 | SIRT6 activator 12q CAS No.2601734-99-8 | SIRT6 activator 12q/CAS No.2601734-99-8 is potent, selective and orally active SIRT6 activator with IC50 values of 171.20, >200, >200, >200, 0.58 μM for SIRT1, SIRT2, SIRT3, SIRT5, SIRT6, respectively. SIRT6 activator 12q inhibits cell growth and migration. SIRT6 activator 12q induces Apoptosis and cell cycle arrest at G2 phase. SIRT6 activator 12q shows anticancer activity. | price> |