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Catalog	name	Description	price
R-R-1972	GK563 CAS No.2351820-19-2	GK563/CAS No.2351820-19-2 is a selective Ca2+-independent phospholipase A2 (GVIA iPLA2) inhibitor with an IC50 value of 1 nM. GK563 is 22000 times more active against GVIA iPLA2 than GIVA cPLA2. GK563 reduces β-cell apoptosis induced by proinflammatory cytokines, raising the possibility that it can be beneficial in countering autoimmune diseases, such as type 1 diabetes.	price>
R-CG-137	mPEG-PGA-g-PEI-g-DXMS（20%）	mPEG-PGA-g-PEI-g-DXMS，Methoxy-poly(ethylene glycol)-poly(L-glutamic acid)-graft-Polyethylenimine-graft-Dexamethasone from ruixi.MPEG copolymerized PGA, and then grafted to Pei. Thus, mpeg-pga-g-pei is formed. Then dexamethasone was grafted onto mpeg-pga-g-pei. Finally, the product was prepared into nanoparticles with positive charge for drug delivery system.	price>
R-M-823	Endotrophin (mouse) trifluoroacetate salt,CAS:1678414-54-4	Endotrophin is a carboxyl-terminal cleavage product of collagen 6 alpha-3 chain which is produced and released by adipocytes and massively upregulated in malignant tumors of breast, liver colon and pancreas. Endotrophin provides a link between obesity and aggressive tumor growth and may serve as sensitive diagnostic marker and valid therapeutic target for designing better strategies to treat cancer and ameliorate obesity-induced insulin resistance.	price>
R-R-1973	Lobetyolin CAS No.129277-38-9	Lobetyolin/CAS No.129277-38-9, a bioactive compound, is derived from Codonopsis pilosula. Lobetyolin has anti-inflammatory, anti-oxidative and xanthine oxidase inhibiting activities. Lobetyolin also induces the apoptosis via the inhibition of ASCT2-mediated glutamine metabolism. Lobetyolin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-DZPE-001	mPEG-PGA-g-PEI	Methoxy-poly(ethylene glycol)-poly(L-glutamic acid)-graft-Polyethylenimine，mPEG-PGA-g-PEI from ruixi.Mpeg-pga-g-pei was obtained by copolymerizing PGA with MPEG and grafting it to Pei.Finally, the product has a drug delivery system.	price>
R-M-824	Endothelin (16-21) trifluoroacetate salt,CAS : 121377-67-1	The endothelin C-terminal fragment HLDIIW was found to be a full agonist at ET-B receptors while being inactive or weakly active at ET-A receptors. The tryptophan in position 21 played a key role in the activity of ET (16-21) at the ET-B receptors.	price>
R-R-1974	9-ING-41 CAS No.1034895-42-5	9-ING-41 (Elraglusib)/CAS No.1034895-42-5 is a maleimide-based ATP-competitive and selective glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 of 0.71 μM. 9-ING-41 significantly leads to cell cycle arrest, autophagy and apoptosis in cancer cells. 9-ING-41 has anticancer activity and has the potential for enhancing the antitumor effects of chemotherapeutic agents.	price>
R-PLF32150	mPEG2000-PLA1300-FITC	Methoxy-poly(ethylene glycol)2k-Poly(D,L-lactide) 1300-FITC,mPEG2000-PLA1300-FITC ,mPEG-PLA-Fluorescein from ruixi.MPEG copolymerized PLA,then fluorescein modified MPEG PLA.Thus forming the final product mPEG2000-PLA1300-FITC.The product can be used in drug delivery system.	price>
R-M-825	Endotoxin Inhibitor	The cyclic peptide KTKCKFLKKC has ben shown to form a strong complex with lipid A, the toxic component of the endotoxin lipopolysaccharide (LPS) . It detoxifies LPS in vitro and prevents LPS-induced cytokine release and lethality in vivo. Furthermore, it shows neither antibiotic activity nor toxicity . KTKCKFLKKC bears a structural resemblance to the peptide antibiotic and endotoxin inhibitor polymyxin B. It could be of use as an adjuvant for antibiotic therapy.	price>
R-R-1975	Fipronil CAS No.120068-37-3	Fipronil/CAS No.120068-37-3 is a broad-spectrum insecticide effective against Lepidoptera species as well as thrips, locusts, ants, cockroaches, fleas and ticks. Fipronil selectively inhibits GABA receptor with IC50s of 30 nM and 1600 nM for cockroach and rat GABA receptors, respectively. Glutamate-gated chloride channels (GluCls), which are present in cockroaches but not in mammals, are sensitive to the blocking effect of Fipronil. Fipronil also induces apoptosis in HepG2 cells and promotes the expression of CYP1A1 and CYP3A4 mRNA in human hepatocytes.	price>
R-PL1435-10k	SH-PEG5k-PLL5k-Folate	Thiol -Poly(ethylene glycol)-Poly(L-lysine)-Folic acid,Thiol -Poly(ethylene glycol)-Poly(L-lysine)-Folate ,SH-PEG5k-PLL5k-Folate ,SH-PEG5k-PLL5k-FA from ruixi.Peg-pll-folate with sulfhydryl functional group and folate group at the end of PEG block was used to prepare nanoparticles and micelles for targeted drug delivery. PLA-PEG is one of the most commonly used biodegradable ABC polymers. Folic acid targeted delivery has become an alternative therapy for many cancer and inflammatory diseases and imaging.	price>
R-M-826	Endotoxin Substrate acetate salt,CAS : 68223-96-1	Boc-LGR-pNA, a chromogenic substrate for horseshoe crab clotting enzyme, which is used in quantitative assays of endotoxin.	price>
R-R-1976	Juglanin CAS No.5041-67-8	Juglanin/CAS No.5041-67-8, a occurring flavonoid that can be isolated from crude Polygonum aviculare, is a JNK acticator, with anti-inflammatory, anti-oxidant and anti-tumor activities. Juglanin can induce apoptosis and autophagy on human breast cancer cells.	price>
R-Y081	Ingenol Mebutate-CY7	Ingenol Mebutate-Cyanine7，Ingenol Mebutate-CY7 from ruixi.Cy7 dye labeling of Morinda macrocarpa methyl butenate.As a kind of cell death inducer, the great Morinda methyl butate is a kind of cell death inducer.Ruixi biotech provides a variety of dyestuffs to mark Morinda macrosomate, such as cy7 dyestuffs, Cy3 dyestuffs, Cy5 dyestuffs, FITC fluorescein and so on.	price>
R-M-827	Axltide trifluoroacetate salt	Axltide trifluoroacetate salt is A substrate for Axl, DDR2, Mst1,and JAK2 kinases.	price>
R-R-1977	CPTH2 CAS No.357649-93-5	CPTH2/CAS No.357649-93-5 is a potent histone acetyltransferase (HAT) inhibitor. CPTH2 selectively inhibits the acetylation of histone H3 by Gcn5. CPTH2 induces apoptosis and decreases the invasiveness of a clear cell renal carcinoma (ccRCC) cell line through the inhibition of acetyltransferase p300 (KAT3B).	price>
R-Y082	Ingenol Mebutate-CY3	Ingenol Mebutate-Cyanine3，Ingenol Mebutate-CY3 from ruixi.Cy3 dye labeling of Morinda macrocarpa methyl butenate.As a kind of cell death inducer, the great Morinda methyl butate is a kind of cell death inducer.Ruixi biotech provides a variety of dyestuffs to mark Morinda macrosomate, such as cy7 dyestuffs, Cy3 dyestuffs, Cy5 dyestuffs, FITC fluorescein and so on.	price>
R-M-828	Autoinducing Peptide I trifluoroacetate salt	Autoinducing peptide (AIP) activating the agr (accessory gene regulator) locus to control the expression of extracellular proteins in S. aureus.	price>
R-R-1978	Almorexant CAS No.871224-64-5	Almorexant (ACT 078573)/CAS No.871224-64-5 is an orally active, potent and competitive dual orexin receptor antagonist, with Kd values of 1.3 nM (OX1) and 0.17 nM (OX2), respectively. Almorexant reversibly blocks signaling of orexin-A and orexin-B peptides. Almorexant totally blocked the intracellular Ca2+ signal pathway. Almorexant stimulates caspase-3 activity in AsPC-1 cells and induces apoptosis.	price>
R-Y083	Ingenol Mebutate-CY5	Ingenol Mebutate-Cyanine5，Ingenol Mebutate-CY5 from ruixi.Cy5 dye labeling of Morinda macrocarpa methyl butenate.As a kind of cell death inducer, the great Morinda methyl butate is a kind of cell death inducer.Ruixi biotech provides a variety of dyestuffs to mark Morinda macrosomate, such as cy7 dyestuffs, Cy3 dyestuffs, Cy5 dyestuffs, FITC fluorescein and so on.	price>

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