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R-9991-2k NH2-PEG-Streptavidin Amine-polyethylene glycol-Streptavidin,NH2-PEG-Streptavidin from ruixi.Streptavidin is a protein with similar biological characteristics to avidin,which is the secretion of Streptomyces avidinii. price>
R-C-420 PEO-b-PAMD Polyethylene oxide(PEO),also known as polyethylene oxide,is a kind of crystalline,thermoplastic water-soluble polymer.It can form complexes with many organic low molecular compounds,polymers and some inorganic electrolytes. price>
R-R-2120 MG-115 CAS No.133407-86-0 MG-115/CAS No.133407-86-0 is a potent and reversible proteasome inhibitor, with Kis of 21 nM and 35 nM for 20S and 26S proteasome, respectively. MG-115 specifically inhibit the chymotrypsin-like activity of the proteasome, induces p53-dependent apoptosis. price>
R-SP-001 Streptavidin-PEG-MAL Streptavidin-polyethylene glycol-Maleimide,Streptavidin-PEG-MAL from ruixi.Streptavidin is a protein with similar biological characteristics to avidin,which is the secretion of Streptomyces avidinii. price>
R-C-421 PEO-b-PTMEG Polyethylene oxide (PEO),also known as polyethylene oxide,is a kind of crystalline,thermoplastic water-soluble polymer.It can form complexes with many organic low molecular compounds,polymers and some inorganic electrolytes. Properties:white vinegar solid,when the temperature exceeds room temperature,it will become transparent liquid.It is soluble in alcohols,esters,ketones,aromatic hydrocarbons and chlorinated hydrocarbons,but insoluble in aliphatic hydrocarbons and water.When the molecular weight increases,the solubility decreases.At room temperature,PTMEG has water absorption.Its water absorption depends on its molecular weight,and it can absorb 2% water at the highest. price>
R-R-2121 Indophagolin CAS No.1207660-00-1 Indophagolin/CAS No.1207660-00-1 is a potent, indoline-containing autophagy inhibitor (IC50=140 nM). Indophagolin antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71, 2.40 and 3.49 μM, respectively. Indophagolin also antagonizes the Gq-protein-coupled P2Y4, P2Y6, and P2Y11 receptors (IC50s =3.4~15.4 μM). Indophagolin has a strong antagonistic effect on serotonin receptor 5-HT6 (IC50=1.0 μM) and a moderate effect on receptors 5-HT1B, 5-HT2B, 5-HT4e, and 5-HT7. price>
RG-F-001 Streptavidin-peg-NHS Streptavidin-polyethylene glycol-N-Hydroxysuccinimide,Streptavidin-peg-NHS from ruixi.Streptavidin is a protein with similar biological characteristics to avidin, which is the secretion of Streptomyces avidinii. price>
R-C-422 PEO-b-PnM Polyethylene oxide (PEO),also known as polyethylene oxide,is a kind of crystalline,thermoplastic water-soluble polymer.It can form complexes with many organic low molecular compounds,polymers and some inorganic electrolytes. Polymethacrylic acid,transparent and fragile solid,soluble in water,soluble in ethylene glycol ether,dimethylformamide, methanol,ethanol,insoluble in acetone and ether. price>
R-R-2122 MMRi62 CAS No.352693-80-2 MMRi62/CAS No.352693-80-2, a ferroptosis inducer targeting MDM2-MDM4 (negative regulators of tumor suppressor p53). MMRi62 shows a P53-independent pro-apoptotic activity against pancreatic ductal adenocarcinoma (PDAC) cells and induce autophagy. MMRi62 inducesferroptosis, resulting in a increase of reactive oxygen and lysosomal degradation of ferritin heavy chain (FTH1). MMRi62 also leads to proteasomal degradation of mutant p53, also inhibits orthotopic xenograft PDAC mouse model in vivo with high frequency mutation characteristics of KRAS and TP53.12. price>
RG-F-002 Streptavidin-peg-cooh Streptavidin-polyethylene glycol-Carboxyl,Streptavidin-peg-cooh from ruixi.Streptavidin is a protein with similar biological characteristics to avidin, which is the secretion of Streptomyces avidinii. price>
R-C-423 PEO-b-PPO Polyethylene oxide (PEO),also known as polyethylene oxide,is a kind of crystalline,thermoplastic water-soluble polymer.It can form complexes with many organic low molecular compounds,polymers and some inorganic electrolytes.The linear polyether is obtained by ring opening polymerization of propylene oxide. Poly(1,2-propanediol ether)with low molecular weight is a random stereopolymer with hydroxyl end. price>
R-R-2123 RapaLink-1 CAS No.1887095-82-0 RapaLink-1/CAS No.1887095-82-0, the third-generation bivalent mTOR inhibitor, combines Rapamycin (HY-10219) with MLN0128 (HY-13328, a second-generation mTOR kinase inhibitor) by an inert chemical linker. RapaLink-1 shows better efficacy than Rapamycin or mTOR kinase inhibitors (TORKi), potently blocking cancer-derived, activating mutants of mTOR. RapaLink-1 can cross the blood-brain barrier. RapaLink-1 binding to FKBP12 results in targeted and durable inhibition of mTORC1. RapaLink-1 plays an antithrombotic role in antiphospholipid syndrome by improving autophagy. Anticancer activity. price>
RG-F-003 Streptavidin-peg-SH Streptavidin-polyethylene glycol-Thiol,Streptavidin-peg-SH from ruixi.Streptavidin is a protein with similar biological characteristics to avidin, which is the secretion of Streptomyces avidinii. price>
R-C-424 PEO-b-PtBuA Homopolymer and copolymer of butyl acrylate.Bulk self polymer is a very soft and sticky colorless transparent rubber material.Polyethylene oxide(PEO),also known as polyethylene oxide,is a kind of crystalline,thermoplastic water-soluble polymer.It can form complexes with many organic low molecular compounds,polymers and some inorganic electrolytes. price>
R-R-2124 Peretinoin CAS No.81485-25-8 Peretinoin/CAS No.81485-25-8 is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as retinoid X receptor (RXR) and retinoic acid receptor (RAR). Peretinoin reduces the mRNA level of sphingosine kinase 1 (SPHK1) in vitro by downregulating a transcription factor, Sp1. Peretinoin prevents the progression of non-alcoholic steatohepatitis (NASH) and the development of hepatocellular carcinoma (HCC) through activating the autophagy pathway by increased Atg16L1 expression. Peretinoin inhibits HCV RNA amplification and virus release by altering lipid metabolism with a EC50 of 9 μM. price>
RG-F-004 Streptavidin-peg-N3 Streptavidin-polyethylene glycol-N3,Streptavidin-peg-Azide from ruixi.Streptavidin is a protein with similar biological characteristics to avidin, which is the secretion of Streptomyces avidinii. price>
R-C-425 PEO-b-PtBUM Tert butyl methacrylate is used as coating,fabric treatment agent and insulating material.Polyethylene oxide (PEO),also known as polyethylene oxide,is a kind of crystalline,thermoplastic water-soluble polymer.It can form complexes with many organic low molecular compounds,polymers and some inorganic electrolytes. price>
R-R-2125 PD98059 CAS No.167869-21-8 PD98059/CAS No.167869-21-8 is a potent and selective MEK inhibitor with an IC50 of 5 µM. PD98059 binds to the inactive form of MEK, thereby preventing activation of MEK1 (IC50 of 2-7 µM) and MEK2 (IC50 of 50 µM) by upstream kinases. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR), and suppresses TCDD binding (IC50 of 4 μM) and AHR processing (IC50 of 1 μM). PD98059 also inhibits autophagy. price>
RG-F-005 Streptavidin-peg-alkyne Streptavidin-polyethylene glycol-Alkyne,Streptavidin-peg-Alkyne from ruixi.Streptavidin is a protein with similar biological characteristics to avidin, which is the secretion of Streptomyces avidinii. price>
R-C-426 PIB-b-PEO Polyethylene oxide(PEO),also known as polyethylene oxide,is a kind of crystalline,thermoplastic water-soluble polymer.It can form complexes with many organic low molecular compounds,polymers and some inorganic electrolytes.The linear polyether pib-peo polyisobutylene block copolymer micelles are formed by ring opening polymerization of propylene oxide.The core-shell structure of the micelles is formed spontaneously by the dissolution of amphiphilic block copolymers in water. price>