Xi'an ruixi Biological Technology Co

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Catalog	name	Description	price
R-R-2126	CLK1-IN-3 CAS No.2922550-28-3	CLK1-IN-3 (compound 10ad)/CAS No.2922550-28-3 is a potent and selective Clk1 inhibitor, with an IC50 of 5 nM and over 300-fold selectivity for Dyrk1A. CLK1-IN-3 also shows a relatively potent inhibition against Clk2 and Clk4, with IC50 values of 42 and 108 nM, respectively. CLK1-IN-3 potently induces autophagy in vitro. CLK1-IN-3 can be used for acute liver injury (ALI) research.	price>
R-Y-C-1031	3-Mercaptopropionic acid modified CdTe (MPA-CdTe QDs)	3-Mercaptopropionic acid modified CdTe，MPA-CdTe QDs from ruixi.3-Mercaptopropionic acid (3-MPA) is used as a self-assembled monolayer (SAM) with a thiol and carboxylic groups. It has short carbon chains and is mainly used as a capping agent on a variety of nanoparticles.3-MPA is used as a capping agent on CdTe quantum dot nanocrystals (QD NCs) that may be used as labeling materials in biomedical applications.	price>
R-C-427	PS-b-PAMD	PAM is full name of polyacrylamide.The molecules of the product can be bridged and adsorbed with the suspended particles dispersed in the solution,which has a strong flocculation effect.	price>
R-R-2127	THZ-P1-2 CAS No.2058075-45-7	THZ-P1-2/CAS No.2058075-45-7 is a first-in-class and selective PI5P4K inhibitor, with an IC50 of 190 nM for PI5P4Kα. THZ-P1-2 covalently targets cysteines on a disordered loop in PI5P4Kα/β/γ. THZ-P1-2 causes autophagy disruption and upregulates TFEB signaling. THZ-P1-2 displays anticancer activity in leukemia cell lines.	price>
R-ICG-009	ICG-β-Cyclodextrin	Indocyanine green modified β - cyclodextrin，ICG-β-Cyclodextrin from ruixi.Indogenine Geen is a kind of negatively charged polymethylene dye, which can combine with protein to form non-public fluorescent complex. ICG can be used to separate several marker proteins, including human serum albumin, nuclease A and transferrin.	price>
R-C-428	PS-b-PANa	Our company cooperates with many well-known domestic laboratories to produce diblock copolymers and triblock copolymers ps-b-pana,pss-b-pmb amphiphilic copolymers.Our company strictly controls the quality of products.All copolymers can provide information such as NMR spectra.The substitution rate and activity purity of products can reach more than 90%.	price>
R-R-2128	Laduviglusib monohydrochloride CAS No.1797989-42-4	Laduviglusib (CHIR-99021) monohydrochloride/CAS No.1797989-42-4 is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib monohydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib monohydrochloride is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusib monohydrochloride enhances mouse and human embryonic stem cells self-renewal. Laduviglusib monohydrochloride induces autophagy.	price>
R-C-429	PSSA-b-PEO	Polyethylene oxide (PEO),also known as polyethylene oxide,is a kind of crystalline,thermoplastic water-soluble polymer.It can form complexes with many organic low molecular compounds,polymers and some inorganic electrolytes.	price>
R-R-2129	Adezmapimod hydrochloride CAS No.869185-85-3	Adezmapimod (SB 203580) hydrochloride/CAS No.869185-85-3 is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively. Adezmapimod hydrochloride inhibits LCK, GSK3β and PKBα with IC50s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod hydrochloride is an autophagy and mitophagy activator.	price>
R-C-430	PDMS-b-PAA	PAA alias acrylic resin emulsion;acrylic modified resin;auxiliary tanning agent; acrylic monomer polymer.Poly two methyl siloxane(Polydimethylsiloxane) is a hydrophobic silicone material,also known as two methyl silicone oil.	price>
R-R-2130	Zeaxanthin dipalmitate CAS No.144-67-2	Zeaxanthin dipalmitate (Physalien)/CAS No.144-67-2 is a wolfberry-derived carotenoid, has anti-inflammatory and anti-oxidative stress effects. Zeaxanthin dipalmitate directly interact with p2X7 receptor (Kd=81.2 nM) and adiponectin receptor 1 (AdipoR1; Kd=533 nM) in a positive dose-dependent manner. Zeaxanthin dipalmitate restores mitochondrial autophagy functions suppressed by ethanol intoxication. Zeaxanthin dipalmitate can be used in the research of alcoholic fatty liver disease (AFLD) and retinitis pigmentosa (RP).	price>
R-C-431	P2VP-b-PEO	P2VP-b-PEO is also a pH responsive amphiphilic polymer.When the pH value changes from acidic to neutral or alkaline,the copolymer formed by poly (2-vinylpyridine) and polyoxyethylene (p2vp-b-peo) can undergo a reversible micellization process in aqueous solution through protonation.P2VP can also make triblock copolymers pH responsive.Lee et al. Developed a series of block copolymers with tertiary amine groups.Their micellization process is pH responsive.	price>
R-R-2131	PF-543 CAS No.1415562-82-1	PF-543 (Sphingosine Kinase 1 Inhibitor II)/CAS No.1415562-82-1 is a potent, selective, reversible and sphingosine-competitive SPHK1 inhibitor with an IC50 of 2 nM and a Ki of 3.6 nM. PF-543 is >100-fold selectivity for SPHK1 over SPHK2. PF-543 is an effective potent inhibitor of sphingosine 1-phosphate (S1P) formation in whole blood with an IC50 of 26.7 nM. PF-543 induces apoptosis, necrosis, and autophagy.	price>
R-C-432	P2VP-b-PMAA	Biodegradable block copolymers are new drug delivery materials with potential development.They can adjust their physical and chemical properties by adjusting the composition of blocks or adding new blocks that meet the requirements.They have good biocompatibility.They are increasingly used as carriers for a variety of drug delivery systems,including non bioactive drugs and bioactive drugs,such as proteins and peptides Antigen,etc.	price>
R-R-2132	Laduviglusib trihydrochloride CAS No.1782235-14-6	Laduviglusib (CHIR-99021) trihydrochloride/CAS No.1782235-14-6 is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib trihydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib trihydrochloride is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusib trihydrochloride enhances mouse and human embryonic stem cells self-renewal. Laduviglusib trihydrochloride induces autophagy.	price>
R-C-433	ABT-888	ABT-888 is an effective inhibitor of PARP.It has good oral bioavailability,can cross the blood-brain barrier,and can enhance temozolomide,platinum, cyclophosphamide and radiation.This broad spectrum of chemical and radioenhancement makes this compound an attractive candidate for clinical evaluation.	price>
R-R-2133	AC-73 CAS No.775294-71-8	AC-73/CAS No.775294-71-8 is a first specific, orally active inhibitor of cluster of differentiation 147 (CD147), which specifically disrupts CD147 dimerization, thereby mainly suppressing the CD147/ERK1/2/STAT3/MMP-2 pathways. AC-73 inhibits the motility and invasion of hepatocellular carcinoma cells. AC-73 is also an anti-proliferative agent and an inducer of autophagy in leukemic cells.	price>
R-C-434	Omipalisib (GSK2126458)	Omipalisib (GSK2126458)is an orally active and highly selective inhibitor of PI3K with Kis of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM for p110α/β/δ/γ,mTORC1/2,respectively.Omipalisib has anti-cancer activity.	price>
R-R-2134	(rel)-ML-SI3 CAS No.2108567-79-7	(rel)-ML-SI3/CAS No.2108567-79-7 is the isomer of ML-SI3 (HY-139426). ML-SI3 is a TRPML Channel Inhibitor. ML-SI3 blocks TRPML1 and TRPML2 with IC50s of 4.7 μM and 1.7 μM, respectively. ML-SI3 prevents lysosomal calcium efflux and blocks downstream TRPML1-mediated induction of autophagy.	price>
R-C-435	BMS777607	Bms-777607 is a met related inhibitor, which acts on c-Met,Axl,Ron and TYRO3 with IC50 of 3.9 nm,1.1 nm,1.8 nm and 4.3 nm respectively in cell-free assay.The selectivity of bms-777607 on met related targets is 40 times higher than that on Lck,VEGFR-2 and TrkA/B,and more than 500 times higher than that on other receptor and non receptor kinases.	price>

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