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Catalog	name	Description	price
R-C-506	Laquinimod cas:248281-84-7	Laquinimod is a potent immunomodulator which prevents neurodegeneration and inflammation in the central nervous system.	price>
R-R-2206	Metformin hydrochloride CAS No.1115-70-4	Metformin hydrochloride/CAS No.1115-70-4 inhibits the mitochondrial respiratory chain in the liver, it can lead to the activation of AMPK and improve insulin sensitivity for type 2 diabetes research. Metformin hydrochloride triggers autophagy.	price>
R-C-507	Mastinib cas:790299-79-5	Masitinib(AB1010)is a potent,orally bioavailable,and selective inhibitor of c-Kit(IC50=200 nM for human recombinant c-Kit).It also inhibits PDGFRα/β(IC50s=540/800 nM),Lyn(IC50= 510 nM for LynB),Lck,and,to a lesser extent,FGFR3 and FAK.Masitinib (AB1010) has anti-proliferative,pro-apoptotic activity and low toxicity.	price>
R-R-2207	EACC CAS No.864941-31-1	EACC/CAS No.864941-31-1 is a reversible autophagy inhibitor, which can block autophagic flux. EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion.	price>
R-C-508	Torcetrapib cas:262352-17-0	Torcetrapib(CP-529414)is a CETP inhibitor with IC50 of 37 nM,elevates HDL-C and reduces nonHDL-C in plasma.	price>
R-R-2208	Gartanin CAS No.33390-42-0	Gartanin/CAS No.33390-42-0 is a natural xanthone of mangosteen, with antioxidant, anti-inflammatory, antifungal, neuroprotective and antineoplastic properties. Gartanin induces cell cycle arrest and autophagy and suppresses migration in human glioma cells.	price>
R-C-509	Tasosartan cas:145733-36-4	Tasosartan is a long-acting angiotensin II(AngII)receptor antagonist.	price>
R-R-2209	DCAP CAS No.500015-20-3	DCAP/CAS No.500015-20-3 is a broad-spectrum antibiotic targeting the membranes of both Gram-positive and Gram-negative bacteria. DCAP blocks autophagy at the late stages by preventing autophagolysosome maturation and interrupting the autophagic flux.	price>
R-C-510	A-803467 cas:944261-79-4	A 803467 is a selective blocker of NaV1.8 channels(IC50 values are 8,2450,6740, 7340 and 7380 nM for hNaV1.8,hNaV1.3,hNaV1.7,hNaV1.5 and hNaV1.2 channels respectively).	price>
R-R-2210	Isorhapontigenin CAS No.32507-66-7	Isorhapontigenin/CAS No.32507-66-7, an orally bioavailable dietary polyphenol isolated from the Chinese herb Gnetum cleistostachyum, displays anti-inflammatory effects. Isorhapontigenin induces autophagy and inhibits invasive bladder cancer formation.	price>
R-C-511	JTC801 cas:244218-51-7	JTC-801 is a selective opioid receptor-like1(ORL1) receptor antagonist with IC50 of 94 nM,weakly inhibits receptors δ,κ,and μ.	price>
R-R-2211	DC-LC3in-D5 CAS No.2868312-73-4	DC-LC3in-D5/CAS No.2868312-73-4 acts as an autophagy inhibitor by attenuating LC3B lipidation. DC-LC3in-D5 binds with LC3B. DC-LC3in-D5 disrupts the LC3B-LBP2 interaction with an IC50 of 200 nM. DC-LC3in-D5 may contribute to anti-HCV or combination researchs in cancer through inhibiting autophagy.	price>
R-C-512	Pyroxamide cas:382180-17-8	Pyroxamide is a potent inhibitor of histone deacetylase 1(HDAC1) with an ID50 of 100 nM.Pyroxamide can in duce apoptosis and cell cycle arrest in leukemia.	price>
R-R-2212	Autogramin-1 CAS No.2375541-73-2	Autogramin-1/CAS No.2375541-73-2 potently inhibits autophagy induced by either starvation (IC50=0.17 μM) or mTORC1 inhibition (Rapamycin; IC50=0.44 μM).	price>
R-C-513	CP466722 cas：1080622-86-1	CP-466722 is a rapidly reversible inhibitor of ATM,with an IC50 of 4.1 μM,and has no effects on PI3K or closely related PI3K-like protein kinase (PIKK) family members.	price>
R-R-2213	U0126 CAS No.109511-58-2	U0126/CAS No.109511-58-2 is a potent, non-ATP competitive and selective MEK1 and MEK2 inhibitor, with IC50s of 72 nM and 58 nM, respectively. U0126 is an autophagy and mitophagy inhibitor.	price>
R-C-514	PF-562771 cas:834894-21-2	AP23464 and PF-562771(AP23848) potently and selectively target activation-loop mutants of Kit in vitro and in vivo and could have therapeutic potential against D816V-expressing malignancies.Src/Abl inhibitors are compatible with imatinib and suggest that combined Abl inhibitor therapy is a feasible treatment strategy for patients with CML.	price>
R-R-2214	STF-62247 CAS No.315702-99-9	STF-62247/CAS No.315702-99-9 is an autophagy inducer that selectively cytotoxic to VHL-deficient renal cell carcinoma (IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively).	price>
R-C-515	TAK285 CAS：871026-44-7	TAK-285 is a potent,selective,ATP-competitive and orally active HER2 and EGFR(HER1)inhibitor with IC50 of 17 nM and 23 nM,respectively.TAK-285 is >10-fold selectivity for HER1/2 than HER4,and less potent to MEK1/5,c-Met,Aurora B,Lck,CSK etc.TAK-285 has effective antitumor activity.TAK-285 can cross the blood-brain barrier(BBB).	price>
R-R-2215	Notoginsenoside Fc CAS No.88122-52-5	Notoginsenoside Fc/CAS No.88122-52-5, a protopanaxadiol- (PPD-) type saponin isolated from the leaves of Panax notoginseng, effectively counteracts platelet aggregation. Notoginsenoside Fc can accelerate reendothelialization following vascular injury in diabetic rats by promoting autophagy.	price>

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