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Catalog	name	Description	price
R-R-2397	Peramivir CAS No.330600-85-6	Peramivir/CAS No.330600-85-6 is an novel cyclopentane neuraminidase inhibitor of influenza virus. Peramivir has antiviral activity and anti-cytokines stom effects. Peramivir can be used for the research of COVID-19.	price>
R-C-698	Amine Functional Mesoporous silica coating NaYF4:Yb,Tm@NaYF4(980 excited, blue light)	The up conversion nanoparticles (980 excited,blue light) with aminated mesoporous silica core-shell structure emit at 365/450/470 nm ±15 nm,the surface ligand is NH2,and the particle size under electron microscope is 50±15.The solvent is water.	price>
R-R-2398	Tetramethylcurcumin CAS No.52328-97-9	Tetramethylcurcumin (FLLL31)/CAS No.52328-97-9, derived from curcumin, specifically suppresses the phosphorylation of STAT3 by binding selectively to Janus kinase 2 and the STAT3 Src homology-2 domain. Tetramethylcurcumin exhibits anti-inflammatory and anti-cancer effects.	price>
R-C-699	Amine Functional Mesoporous silica coating NaYF4,Yb,Er@NaYF4,Yb,Nd(808 excitation, green light)	Amino mesoporous silica coated core-shell upconversion nanoparticles (808 excitation, green light) have an emission wavelength of 540/650 nm±15 nm,a surface ligand of NH2,and a particle size of 50 ± 15 under electron microscope. The solvent is water.	price>
R-R-2399	(R)-Lisofylline CAS No.100324-81-0	(R)-Lisofylline ((R)-Lisophylline)/CAS No.100324-81-0 is a (R)-enantiomer of the metabolite of Pentoxifylline with anti-inflammatory properties. (R)-Lisofylline is a lysophosphatidic acid acyltransferase inhibitor with an IC50 of 0.6 µM and interrupts IL-12 signaling-mediated STAT4 activation. (R)-Lisofylline has the potential for type 1 diabetes, autoimmune disorders research.	price>
R-C-700	Amine Functional Mesoporous silica coating NaYF4,Yb,Tm@NaYF4,Yb,Nd(808 excited, blue light)	Amine Functional Mesoporous silica coating NaYF4,Yb,Tm@NaYF4,Yb,Nd(808 excited, blue light),The emission wavelength is 365/450/470nm15 nm,the surface ligand is NH2,the particle size under electron microscope is 50±15,and the solvent is water.	price>
R-R-2400	STAT3-IN-15	STAT3-IN-15 is a potent and orally active STAT3 inhibitor against idiopathic pulmonary fibrosis (IPF). STAT3-IN-15 inhibits STAT3 phosphorylation. STAT3-IN-15 also inhibits the migration and deformation of epithelial cells induced by TGF-β1 and inhibit epithelial-mesenchymal transition (EMT).	price>
R-C-701	Streptavidin modified NaYF4:Yb,Er(980 excitation, green light)	Streptavidin modified upconversion nanoparticles (980 excitation, green light),The emission wavelength is 540/650 nm±15 nm,the surface ligand is streptavidin,the particle size is 20-30 nm under electron microscope,and the solvent is water.	price>
R-R-2401	W1131 CAS No.2740522-79-4	W1131/CAS No.2740522-79-4 is a potent STAT3 inhibitor, triggering ferroptosis. W1131 suppresses cancer progression in gastric cancer cell subcutaneous xenograft model, organoids model, and PDX model. W1131 effectively alleviates chemical resistance of cancer cells to 5-FU (HY-90006). W1131 regulates cell cycle, DNA damage response, and oxidative phosphorylation, including IL6-JAK-STAT3 pathway and ferroptosis pathway.	price>
R-C-702	Streptavidin modified NaYF4:Yb,Tm (980 excitation, blue light)	Streptavidin modified upconversion nanoparticles(980 excitation,blue light), The emission wavelength is 365/450/470nm±15 nm,the surface ligand is streptavidin,and the particle size is 20-30nm under electron microscope.The solvent is water.	price>
R-R-2402	ENMD-1198 CAS No.864668-87-1	ENMD-1198 (IRC-110160)/CAS No.864668-87-1, an orally active microtubule destabilizing agent, is a 2-methoxyestradiol analogue with antiproliferative and antiangiogenic activity. ENMD-1198 is suitable for inhibiting HIF-1alpha and STAT3 in human HCC cells and leads to reduced tumor growth and vascularization.	price>
R-C-703	Streptavidin modified NaYF4:Yb,Er@NaYF4(980 excitation, green light)	Streptavidin modified core-shell upconversion nanoparticles(980 excitation,green light),The emission wavelength is 540/650 nm±15 nm,the surface ligand is streptavidin,the particle size is 30-40 nm under electron microscope,and the solvent is water.	price>
R-R-2403	C188 CAS No.823828-18-8	C188/CAS No.823828-18-8 is a STAT3 inhibitor that inhibits IL-6-stimulated STAT3 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket. C188, in particular, was highly active in inducing apoptosis of the breast cancer cell line MB-MDA-468 in vitro (EC50= 0.7 μM).	price>
R-C-704	Streptavidin modified NaYF4:Yb,Tm@NaYF4(980 excitation, blue light),core-shell	Streptavidin modified core-shell upconversion nanoparticles(980 excitation,blue light),The emission wavelength is 365/450/470 nm ±15 nm,the surface ligand is streptavidin,and the particle size is 30-40 nm under electron microscope.	price>
R-R-2404	CMD178 TFA	CMD178 TFA is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development.	price>
R-C-705	Streptavidin modified NaYF4,Yb,Er@NaYF4,Yb,Nd(808 excited, green light),core-shell	Streptavidin modified core-shell upconversion nanoparticles (808 excited,green light),The emission wavelength is 540/650 nm±15 nm,the surface ligand is streptavidin,the particle size is 30-40 nm under electron microscope,and the solvent is water.	price>
R-R-2405	Stafib-2 CAS No.2097938-74-2	Stafib-2/CAS No.2097938-74-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with an IC50 of 82 nM and 1.7 μM for STAT5b and STAT5a, respectively. Stafib-2 exhibits poor cell permeability.	price>
R-C-706	Streptavidin modified NaYF4,Yb,Tm@NaYF4,Yb,Nd(808 excited, blue light),core-shell	Streptavidin modified core-shell upconversion nanoparticles(808 excited,blue light). The emission wavelength is 365/450/470 nm±2 nm,the surface ligand is streptavidin,and the particle size is 30-40 nm under electron microscope.	price>
R-R-2406	Niclosamide-13C6 CAS No.1325808-64-7	Niclosamide-13C6/CAS No.1325808-64-7 is the 13C6 labeled Niclosamide. Niclosamide (BAY2353) is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Niclosamide (BAY2353) inhibits STAT3 with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay.	price>
R-C-707	Biotin NaYF4:Yb,Er(980 excitation, green light)	Biotin modified upconversion nanoparticles(980 excitation,green light),The emission wavelength is 540/650 nm±15 nm,the surface ligand is biotin,the particle size is 20-30 nm under electron microscope,and the solvent is water.	price>

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