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Catalog	name	Description	price
R-R-2407	ML115 CAS No.912798-42-6	ML115/CAS No.912798-42-6 is a molecular probe of the signal transducer and activator of transcription (STAT3). ML115 is a STAT3 agonist.	price>
R-C-708	Biotin NaYF4:Yb,Tm(980 excitation, blue light)	Biotin modified upconversion nanoparticles (980 excitation,blue light),The emission wavelength is 365/450 /470 nm±15 nm,the surface ligand is biotin,the particle size is 20-30 nm under electron microscope,and the solvent is water.	price>
R-R-2408	Bruceantinol CAS No.53729-52-5	Bruceantinol/CAS No.53729-52-5, a quassinoid isolated from Brucea javanica, inhibits pepper mottle virus in pepper. Bruceantinol is a STAT3 inhibitor demonstrating potent antitumor activity in in vitro and in vivo human colorectal cancer (CRC) models. Bruceantinol strongly inhibits STAT3 DNA-binding ability (IC50=2.4 pM), blocks the constitutive and IL-6-induced STAT3 activation, and suppresses transcription of MCL-1, PTTG1, survivin and c-Myc.	price>
R-C-709	Biotin NaYF4:Yb,Er@NaYF4(980 excitation, green light)	Biotin modified core-shell upconversion nanoparticles(980 excitation,green light),The emission wavelength is 540/650 nm±15 nm,the surface ligand is biotin, the particle size is 30-40 nm under electron microscope,and the solvent is water.	price>
R-R-2409	Salviolone CAS No.119400-86-1	Salviolone/CAS No.119400-86-1 is a natural diterpenoid derivative that can against melanoma cells. Salviolone exhibits a pleiotropic effect against melanoma by hampering cell cycle progression, STAT3 signaling, and malignant phenotype of A375 melanoma cells.	price>
R-C-710	Biotin NaYF4:Yb,Tm@NaYF4(980 excitation, blue light)	Biotin modified core-shell upconversion nanoparticles(980 excitation,blue light),The emission wavelength is 365/450/470 nm±15 nm,the surface ligand is biotin,the particle size is 30-40 nm under electron microscope,and the solvent is water.	price>
R-R-2410	APTSTAT3-9R	APTSTAT3-9R, a specific STAT3-binding peptide, inhibits STAT3 activation and downstream signaling by specifically blocking STAT3 phosphorylation. APTSTAT3-9R exerts antiproliferative effects and antitumor activity.	price>
R-C-711	Biotin NaYF4,Yb,Er@NaYF4,Yb,Nd(808 excited, green light)	Biotin modified core-shell upconversion nanoparticles (808 excited,green light),The emission wavelength is 540/650 nm±15 nm,the surface ligand is biotin, the particle size is 30-40 nm under electron microscope, and the solvent is water.	price>
R-R-2411	MM-206 CAS No.1809581-87-0	MM-206/CAS No.1809581-87-0, a STAT3 activity inhibitor, potently inhibits the STAT3 SH2 domain-phosphopeptide interaction with IC50 of 1.2 μM. MM-206 demonstrates dose-dependent induction of apoptosis in acute myeloid leukemia (AML) cell lines.	price>
R-C-712	Biotin NaYF4,Yb,Tm@NaYF4,Yb,Nd(808 excited, blue light)	Biotin modified core-shell upconversion nanoparticles(808 excited,blue light),The emission wavelength is 365/450/470 nm±15 nm,the surface ligand is biotin,the particle size is 30-40 nm under electron microscope,and the solvent is water.	price>
R-R-2412	STAT3-IN-7 CAS No.1313019-65-6	STAT3-IN-7/1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea/CAS No.1313019-65-6 is a Sorafenib analogue and potently inhibits the phosphorylation of STAT3. STAT3-IN-7 induces cell apoptosis through SHP-1 dependent STAT3 inactivation. STAT3-IN-7 does not inhibit kinase activity and has anticancer effects.	price>
R-C-713	SB525334 cas:356559-20-1	SB525334 is a selective inhibitor of transforming growth factor-β receptor I (ALK5,TGF-βRI)(IC50=14.3 nM).Inhibits TGF-β1-induced smad2/3 nuclear localization and TGF-βRI-induced mRNA expression in kidney cells.	price>
R-R-2413	Stafia-1-dipivaloyloxymethyl ester CAS No.2582755-72-2	Stafia-1-dipivaloyloxymethyl ester (compound 27, 0-200 μM)/CAS No.2582755-72-2 decreases pSTAT5a expression significantly, and has no obvious inhibition on pSTAT5b.	price>
R-C-714	UNC-669 cas:1314241-44-5	UNC669 is a small-molecule antagonist of methyl-lysine(KMe)reader protein with selectivity for L3MBTL1 and L3MBTL3(IC50 of 4.2μM and 3.1μM respectively).	price>
R-R-2414	Eupalinolide K CAS No.108657-10-9	Eupalinolide K/CAS No.108657-10-9, a sesquiterpene lactones compound from Eupatorium lindleyanum, is a STAT3 inhibitor. Eupalinolide K is a Michael reaction acceptor (MRA) .	price>
R-C-715	Birinapant cas:1260251-31-7	Birinapant,also known as TL32711,is a synthetic small molecule and peptido mimetic of second mitochondrial-derived activator of caspases(SMAC) and inhibitor of IAP(Inhibitor of Apoptosis Protein)family proteins,with potential antineoplastic activity.	price>
R-R-2415	W1131 TFA	W1131 TFA is a potent STAT3 inhibitor that induces ferroptosis. W1131 inhibits cancer progression in subcutaneous xenograft, organoid, and PDX models of gastric cancer. W1131 effectively alleviates cancer cell chemoresistance to 5-FU (HY-90006). W1131 regulates the cell cycle, DNA damage response, and oxidative phosphorylation, including the IL6-JAK-STAT3 pathway and the ferroptosis pathway.	price>
R-C-716	MK2206 cas:1032350-13-2	MK-2206 dihydrochloride(MK-2206 (2HCl))is an orally active allosteric AKT inhibitor with IC50s of 5 nM,12 nM,and 65 nM for AKT1,AKT2, and AKT3,respectively.MK-2206 dihydrochloride induces autophagy.	price>
R-R-2416	Balsalazide sodium hydrate CAS No.150399-21-6	Balsalazide sodium hydrate/CAS No.150399-21-6 could suppress colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway.	price>
R-C-717	CYT387（Momelotinib） CAS:1056634-68-4	Momelotinib(CYT387)is an ATP-competitive inhibitor of JAK1/JAK2 with IC50a of 11 nM and 18 nM,respectively.CYT387 shows much less activity against JAK3.	price>

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