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Catalog	name	Description	price
R-R-2470	MI-463 CAS No.1628317-18-9	MI-463/CAS No.1628317-18-9 is a highly potent and orally bioavailable small molecule inhibitor of the menin-mLL interaction.	price>
R-R-2471	GSK 4027 CAS No.2079896-25-4	GSK 4027/CAS No.2079896-25-4 is a chemical probe for the PCAF/GCN5 bromodomain with an pIC50 of 7.4±0.11 for PCAF in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay.	price>
R-C-772	PEO2200-b-PS10000	Poly(ethylene oxide)(PEO)has good hydrophilicity.A series of polymer dispersants can be prepared by block copolymerization,graft copolymerization or random copolymerization.By adjusting the proportion of oleophilic blocks,the adsorption stability between oleophilic blocks and particles can be enhanced,and the stability of suspension polymerization process can be effectively improved.	price>
R-R-2472	PROTAC BRD9 Degrader-1 CAS No.2097971-01-0	PROTAC BRD9 Degrader-1/CAS No.2097971-01-0 is a PROTAC BRD9 lead chemical degrader (IC50=13.5 nM), which can be used as a useful selective probe for studying the complex biology of BAF.	price>
R-C-773	PLL5k-g-PEG5k-MAL	Poly(L-lysine)-g-poly (ethylene glycol)-maleimide is produced by Ruixi bio. Poly(L-lysine)-g-poly (ethylene glycol)-maleimide is linked with poly(ethylene glycol),and the other end of poly(ethylene glycol)is modified with maleimide.We can provide more customized products.	price>
R-R-2473	BI-9564 CAS No.1883429-22-8	BI-9564/CAS No.1883429-22-8 is a potent, selective and cell-permeable BRD9/BRD7 bromodomains inhibitor, with IC50s of 75 nM and 3.4 μM and Kds of 14 nM and 239 nM, respectively. BI-9564 has an IC50 of > 100 μM for BET family.	price>
R-C-774	PEI coating Fe3O4 nanoparticles（50nm）	This product is Fe3O4 magnetic nanoparticles with particle size of 50nm,coated with Pei(polyethyleneimine)with different molecular weight,used for biomolecular coupling,immobilization,nanoprobe construction,etc.	price>
R-R-2474	I-CBP112 CAS No.1640282-31-0	I-CBP112/CAS No.1640282-31-0 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor, that inhibits the CBP/p300 bromodomains, enhances acetylation by p300.	price>
R-C-775	25-35nm silica coated nano silver 60nm	This product is surface chemistry and coatings.Silver nanoparticles have a variety of anionic and cationic blocking ligands,from replaceable small molecules to polymer coatings.Standard(silanol)silica surfaces of silica shell silver nanospheres increase stability in a wide range of solvents.	price>
R-R-2475	SGC-iMLLT CAS No.2255338-25-9	SGC-iMLLT/CAS No.2255338-25-9 is a first-in-class chemical probe and a potent, selective inhibitor of MLLT1/3-histone interactions with an IC50 of 0.26 μM. SGC-iMLLT shows high binding activity towards MLLT1 YEATS domain (YD) and MLLT3 YD (AF9/YEATS3) with Kds of 0.129 and 0.077 μM, respectively.	price>
R-C-776	Colloidal gold modified azide	Colloidal gold modified azide compounds can be used for click chemistry based chemical reactions.	price>
R-R-2476	GNE-272 CAS No.1936428-93-1	GNE-272/CAS No.1936428-93-1 is a potent and selective CBP/EP300 inhibitor with IC50 values of 0.02, 0.03, and 13 μM for CBP, EP300, and BRD4, respectively. GNE-272 is also an in vivo selective probe for CBP/EP300.	price>
R-C-777	Modification of alkynyl group with colloidal gold	Colloidal gold is a kind of stable colloidal state,called colloidal gold,which is polymerized by the chlorogold(HAuCl4)under the action of reducing agents such as white phosphorus,ascorbic acid,sodium citrate and tannin.	price>
R-R-2477	GNE-987 CAS No.2417371-71-0	GNE-987/CAS No.2417371-71-0 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. GNE-987 exhibits picomolar cell BRD4 degradation activity (DC50=0.03 nM for EOL-1 AML cell line). GNE-987 binds equipotently to the BD1 and BD2 bromodomains of BRD4 with low nanomolar affinities (IC50=4.7 and 4.4 nM, respectively). GNE-987 incorporates a potent BET binder/inhibitor, a VHL-binding fragment, and a ten methylene spacer moiety. GNE-987 can be used in PROTAC-Antibody Conjugate (PAC).	price>
R-R-2478	MS645 CAS No.2250091-96-2	MS645/CAS No.2250091-96-2 is a bivalent BET bromodomains (BrD) inhibitor with a Ki of 18.4 nM for BRD4-BD1/BD2. MS645 spatially constrains bivalent inhibition of BRD4 BrDs resulting in a sustained repression of BRD4 transcriptional activity in solid-tumor cells.	price>
R-C-779	NOTA-NHS ester	Macrocyclic ligands and their use as MRI contrast agents,including bifunctional chelating agents,macrocyclic ligands,magnetic resonance reagents,reaction intermediates and a series of products.NHS(N-hydroxysuccinimide)esters and other active esters(sulfo NHS, sulfotetrafluorophenyl STP)are suitable for amino modification.NHS is the most common active ester.The common modifications are fluorescent labeling,fluorescence quenching agent and other reporter groups.	price>
R-R-2479	dBET57 CAS No.1883863-52-2	dBET57/CAS No.1883863-52-2 is a potent and selective degrader of BRD4BD1 based on the PROTAC technology. dBET57 mediates recruitment to the CRL4Cereblon E3 ubiquitin ligase, with a DC50/5h of 500 nM for BRD4BD1, and is inactive on BRD4BD2.	price>
R-R-2480	ZL0580 CAS No.2377151-10-3	ZL0580/CAS No.2377151-10-3, a structurally close analog of ZL0590, induces epigenetic suppression of HIV via selectively binding to BD1 domain of BRD4. ZL0580 induces HIV suppression by inhibiting Tat transactivation and transcription elongation as well as by inducing repressive chromatin structure at the HIV promoter.	price>
R-R-2481	PROTAC BRD4 ligand-1 CAS No.2313230-51-0	PROTAC BRD4 ligand-1/CAS No.2313230-51-0 is a potent BET inhibitor and a ligand for target BRD4 protein for PROTACT GNE-987 (HY-129937A).	price>
R-C-782	MAL-PEG113-PLys	Maleimide is an organic compound,chemical formula is c4h3no2,flake crystal,easy to sublimate,soluble in water,ether and ethanol.Polyethylene glycol(PEG)is a kind of high molecular polymer,which has no irritation,slightly bitter taste,good water solubility and good compatibility with many organic components.The two ends of PEG are linked with mal and polylysine.	price>

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