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Catalog | name | Description | price |
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R-R-2493 | SIM1 CAS No.2719051-84-8 | SIM1/CAS No.2719051-84-8 is a potent von Hippel-Lindau (VHL)-based trivalent PROTAC capable of degradation for all BET family members, with preference for BRD2 degradation (IC50=1.1 nM; Kd=186 nM). SIM1 shows sustained anti-cancer activity. | price> |
R-C-794 | PLL4300-PEG2000-modified Gold Nanoparticles(5nm) | Gold nanoparticles:they have good chemical inertness.Gold is one of the first metals found in history.Gold nanoparticles are also widely studied in Inorganic Chemistry and nanomaterials. | price> |
R-R-2494 | dBRD9 CAS No.2170679-45-3 | dBRD9/CAS No.2170679-45-3,a PROTAC, can selective degrades BRD9. dBRD9 improves the bromine domain binding profile and reduces the binding activity of the whole BET family. | price> |
R-C-795 | Paclitaxel | Paclitaxel can make tubulin and tubulin dimer of microtubule lose dynamic balance,induce and promote tubulin polymerization,microtubule assembly,prevent depolymerization,so as to stabilize microtubule,inhibit the mitosis of cancer cells and trigger apoptosis,and then effectively prevent the proliferation of cancer cells and play an anti-cancer role. | price> |
R-R-2495 | PROTAC CBP/P300 Degrader-1 CAS No.2484739-48-0 | PROTAC CBP/P300 Degrader-1/CAS No.2484739-48-0 is a potent PROTAC CBP/P300 degrader. PROTAC CBP/P300 Degrader-1 potently inhibited cell viability of multiple cancer cell lines. | price> |
R-C-796 | DSPE-PEG2000-Alendronate sodium | Alendronate sodium tablets,a bone metabolism regulator,is an aminodiphosphonate with strong affinity for hydroxyapatite in bone.When the osteoclasts dissolve the crystals,the drug is released,which can inhibit the activity of osteoclasts and indirectly inhibit bone resorption through osteoblasts.It is characterized by strong anti bone resorption activity and no inhibition of bone mineralization. | price> |
R-R-2496 | FHD-609 CAS No.2676211-64-4 | FHD-609/CAS No.2676211-64-4 is an inhibitor and a degrader of BRD9 (bromodomain-containing protein 9). FHD-609 targets to ncBAF, can be used for research of wide range of cancers that contain a mutation in a BAF complex subunit. FHD-609 in combination with Telomelysin or INO5401, may play a role in adrenocortical carcinoma (ACC) treatment. | price> |
R-C-797 | DSPE-PEG2000-ASP8 | PEG and DSPE are connected by carbamate bond.There are two saturated acyl chains. The lipophilic end is DSPE and the hydrophilic end is peg.The connection between PEG and liposome is firm and the ability to protect liposome from damage is the strongest.Asp8,which is similar to the hydroxyapatite binding domain of osteopontin and osteocalcin,has been used as a bone targeting part for the exclusive delivery of drugs to bone. | price> |
R-R-2497 | I-BET762 carboxylic acid CAS No.1300019-38-8 | I-BET762 carboxylic acid (Molibresib carboxylic acid)/CAS No.1300019-38-8 is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid (Molibresib carboxylic acid) is a BRD4 inhibitor with a pIC50 of 5.1. | price> |
R-C-798 | DSPE-PEG2000-ss31 | PEG and DSPE are connected by carbamate bond.There are two saturated acyl chains. The lipophilic end is DSPE and the hydrophilic end is peg.The connection between PEG and liposome is firm and the ability to protect liposome from damage is the strongest.Ss31 is a novel peptide with mitochondrial protection,which is composed of basic amino acids and aromatic amino acids alternately(h-d-arg-dmt-lys-phe-nh2).Ss31 has the characteristics of low toxicity,high activity and easy to penetrate through the cell membrane.In particular,ss31 can be targeted to the inner membrane of mitochondria. | price> |
R-R-2498 | TCIP 1 CAS No.3005886-78-9 | TCIP 1/CAS No.3005886-78-9 is a transcriptional/epigenetic CIPs (TCIP) small molecule consisting of covalent links to small molecules capable of binding to BCL6 and capable of binding to BRD4, respectively. TCIPs aids cell death gene expression by recruiting endogenous cancer drivers or downstream transcription factors to the promoters of cell death genes. TCIP 1 also plays a gain-of-function mechanism with shows cell specificity and tissue specificity. TCIP 1 forms a gain-of-function ternary complex with BCL6 and BRD4, Inhibits the blocking effect of BCL6 on apoptosis gene, and generates transcriptional extension of pro-apoptotic genes, thus activates apoptosis. TCIP 1 also significantly inhibits the expression of the oncogene MYC and inhibits the growth of diffuse large B-cell lymphoma (DLBCL). | price> |
R-C-799 | PLGA5K-TK-PEG2K-FA | Ruixibio can provide poly(l-lactic-co-glycolide)-thioacetal polyethylene glycol folic acid.Keto mercaptan(TK)is the ROS response group.Keto mercaptan polymers are widely used in inflammation and tumor.Inflammation and tumor have high levels of ROS,which can break keto mercaptan chemical bond and realize drug release. | price> |
R-R-2499 | BPTF-IN-BZ1 CAS No.2766623-38-3 | BPTF-IN-BZ1/CAS No.2766623-38-3, a BPTF inhibitor, possesses a high potency (Kd = 6.3 nM). | price> |
R-C-800 | NHS-PEG8-MAL | N-hydroxylsuccinimide(NHS)-polyethylene glycol-maleimide,NHS-PEG-MAL is a linear heterobifunctional PEG reagent with a maleimide and a NHS ester group,Maleimide reacts with thiol,SH,sulfhydryl,NHS ester group can react with primary amine. | price> |
R-R-2500 | GSK-5959 CAS No.901245-65-6 | GSK-5959/CAS No.901245-65-6 is a potent, selective and cell permeable BRPF1 bromodomain inhibitor with an IC50 of ~ 80 nM. | price> |
R-C-801 | Ovalbumin-Folic acid | Ovalbumin(OVA)is the main protein found in egg white,accounting for about 55% of the total protein.Ovalbumin shows sequence and three-dimensional homology with serpin superfamily,but unlike most serpins,it is not a serine protease inhibitor. Folic acid is a water-soluble vitamin with the molecular formula of c19h19n7o6. Because the content of green leaves is very rich and named,also known as polyglutamic acid. | price> |
R-R-2501 | FHT-1204 CAS No.2468048-24-8 | FHT-1204/CAS No.2468048-24-8 is a potent SMARCA4/SMARCA2 ATPase (BRG1 and BRM) inhibitor with IC50s of ≤10 nM (WO2020160180A1; compound 70). | price> |
R-C-802 | Thiol Functional Fe3O4 nanoparticles(10-30nm) | Sulfhydryl functionalized Fe3O4 nanoparticles with particle size of 50 nm were dispersed in water,and the terminal active groups could react with mal. | price> |
R-R-2502 | GNE-064 CAS No.1997321-20-6 | GNE-064 (compound 5)/CAS No.1997321-20-6 is a selective, orally active and highly soluble inhibitor of SMARCA4, SMARCA2 and PBRM1 bromodomains 5. GNE-064 inhibits SMARCA4 with an IC50 of 0.035 μM and inhibits SMARCA2 with an EC50 of 0.10 μM. GNE-064 possess Kds with 0.01, 0.016, 0.018 and 0.049 μM for SMARCA4, SMARCA2, PBRM1 bromodomains 5 and PBRM1 bromodomains 2, repectively. GNE-064 can be used as a chemical probe for the research of agent synthesis. | price> |
R-C-803 | CsPbI3 | Cspbi3 spin coating solution is a product of RuixibiotechCo.Ltd.It contains other metals.Other kinds of perovskite spin coating solution can also be found.The product is mainly used as thin film battery.The product concentration:40wt%, solvent:DMF DMSO(3:1)mixed solvent.Concentration and solvent are other. | price> |