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Catalog | name | Description | price |
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R-R-2514 | DN02 | DN02 is a potent, selective BRD8 bromodomain probe. DN02 has exhibits high affinity for the BRD8(1) (Ki=32 nM), which is 30-fold more affinity than BRD8 (2) (Ki>1000 nM). | price> |
R-C-815 | PLGA5000-PEG5000-DOTA-FA | Poly(lactic co glycolic acid)(PLGA)is a kind of degradable functional polymer, which is randomly polymerized by two monomers,lactic acid and glycolic acid.It has good biocompatibility,non toxicity,and good properties of encapsulation and film formation. | price> |
R-R-2515 | QCA570 CAS No.2207569-08-0 | QCA570/CAS No.2207569-08-0 is a PROTAC connected by ligands for Cereblon and BET, with an IC50 of 10 nM for BRD4 BD1 Protein. | price> |
R-C-816 | PLGA microspheres labeled with CY7(100-200nm) | RuixibiotechCo.Ltd.It is a well-known polymer supplier in China.At present,our company can also provide a series of polymer microspheres or fluorescent polymer microspheres.At the same time,our company can also provide silica microspheres and fluorescent silica microspheres,PS polystyrene microspheres and fluorescent polystyrene microspheres. | price> |
R-R-2516 | BRD7-IN-1 CAS No.2448414-48-8 | BRD7-IN-1/CAS No.2448414-48-8, a modified derivative of BI7273 (BRD7/9 inhibitor), binds to a VHL ligand via a linker to form a PROTAC VZ185 (VZ185 against BRD7/9 with DC50s of 4.5 and 1.8 nM, respectively). | price> |
R-C-817 | FITC microspheres labeled with CY7(100-200nm) | Ruixi Biotechnology Co.,Ltd.is a well-known polymer supplier in China.At present, our company can also provide a series of polymer microspheres or fluorescent polymer microspheres.At the same time,our company can also provide silica microspheres and fluorescent silica microspheres,PS polystyrene microspheres and fluorescent polystyrene microspheres. | price> |
R-R-2517 | dBET23 CAS No.1957234-83-1 | dBET23/CAS No.1957234-83-1 is a highly effective and selective PROTAC BRD4 degrader with a DC50/5h of ~ 50 nM for BRD4BD1 protein. | price> |
R-C-818 | Sodium citrate modified gold nanorods | Social citrate modified gold nanoods has good biocompatibility and is easy to be functionalized.It has photothermal effect and excellent penetration to biological tissue.It can be used in photothermal therapy,biological immunoassay,dark field optical imaging,two-photon fluorescence,surface Raman enhancement,drug carrier and so on. | price> |
R-R-2518 | BRD4 Inhibitor-10 CAS No.1660117-38-3 | BRD4 Inhibitor-10/CAS No.1660117-38-3 is a potent BRD4-BD1 inhibitor extracted from patent WO2015022332A1, Compound II-25, has an IC50 of 8 nM. | price> |
R-C-819 | Carbon nanotubes, single wall, carboxylic acid functionalization | Carbon nanotube is a kind of one-dimensional quantum material with special structure(radial size is nanometer, axial size is micron,and both ends of the tube are basically sealed).Carbon nanotubes can be made into transparent conductive thin films to replace indium tin oxide as the material of touch screen. | price> |
R-R-2519 | AZ13824374 | AZ13824374 is a highly potent and selective ATAD2 bromodomain inhibitor which shows cellular target engagement and antiproliferative activity in a range of breast cancer models. AZ13824374 inhibits ATAD2 with pIC50s of 8.2 and 6.2 in ATAD2 FRET assay and ATAD2 NanoBRET assay, respectively. | price> |
R-C-820 | PLA4k-PHis4k-hyd-PEG4k | Ruixibio sells research products related to nano targeted drug delivery systems, including synthetic phospholipids,polyethylene glycol derivatives,block copolymers,gold nanoparticles,magnetic nanoparticles and fluorescent dyes. | price> |
R-R-2520 | GSK8814 CAS No.1997369-78-4 | GSK8814/CAS No.1997369-78-4 is a potent, selective, and ATAD2/2B bromodomain chemical probe and inhibitor, with a binding constant pKd=8.1 and a pKi=8.9 in BROMOscan. GSK8814 binds to ATAD2 and BRD4 BD1 with pIC50s of 7.3 and 4.6, respectively. GSK8814 shows 500-fold selectivity for ATAD2 over BRD4 BD1. | price> |
R-C-821 | PLL10k-Ce6 | CE6 is usually synthesized from pheophorbidic acid A.It is a good photosensitizer with similar biological activity to pheophorbidic acid a.CE6 is highly efficient in producing singlet oxygen because it is suitable for developing photodynamic therapy for tumors.CE6 photosensitizer coupled magnetic nanoprobe. | price> |
R-R-2521 | NI-57 CAS No.1883548-89-7 | NI-57/CAS No.1883548-89-7 is an inhibitor of bromodomain and plant homeodomain finger-containing (BRPF) famlily of proteins, with IC50s of 3.1, 46 and 140 nM for BRPF1, BRPF2 (BRD1) and BRPF3, respectively. | price> |
R-C-822 | chrysophanic acid-SS-PLL10K-Ce6 | CE6 is usually synthesized from demethylated folate a,which is a photosensitizer with similar biological activity to demethylated folate a.CE6 has the ability to generate singlet oxygen efficiently,which is suitable for the development of photodynamic therapy.CE6 photosensitizer coupled magnetic nanoprobe.Rhubarb can inhibit the production of antibody,inhibit the ability of carbon clearance, reduce the weight of immune organs and reduce the number of white cells. | price> |
R-R-2522 | MT1 CAS No.2060573-82-0 | MT1/CAS No.2060573-82-0 is a bivalent chemical probe of BET bromodomains, with an IC50 of 0.789 nM for BRD4. | price> |
R-C-823 | Cis-aconitic anhydride-d-tyrosine(CA-DTyr) | The surface of polyethersulfone(PES)membrane was modified with D-Tyrosine to improve the hydrophilicity and antibacterial properties of the membrane surface, thus alleviating the membrane biofouling.The surface hydrophilicity of the membrane was increased,the roughness was reduced,and the permeability of the membrane was not affected. | price> |
R-R-2523 | GNE-375 CAS No.1926989-06-1 | GNE-375/CAS No.1926989-06-1 is a potent and highly selective BRD9 inhibitor with an IC50 of 5 nM. GNE-375 shows >100-fold selective for BRD9 over BRD4, TAF1, and CECR2. GNE-375 decreases BRD9 binding to chromatin. | price> |
R-C-824 | Bleomycin hydrochloride(cas:67763-87-5) | Bleomycin hydrochloride is a member of bleomycin putrefycin antibiotic family.It is a water-soluble,copper ion chelating glycoprotein antibiotic isolated from Streptomyces verticillius.The presence of copper ions makes the solution blue. The chelating form of copper ion is inactive.When antibiotics enter the cell, cu2+is reduced to cu+,and is removed by the mercaptol compounds in the cell.At this time,bleomycin hydrochloride is activated and combined with DNA,and DNA is cut,which causes cell death.The protein encoded by the bleomycin tolerance gene (SH ble)can bind with bleomycin hydrochloride and inhibit the DNA cutting by bleomycin hydrochloride.Bleomycin hydrochloride has a wide spectrum of action, which has strong antibacterial activity to bacteria,fungi(including yeast), plants and mammalian cells.Therefore,bleomycin hydrochloride is often used as a very effective tool antibiotic to screen a cell line with SH ble resistance gene and stably express 13.665 kDa. | price> |