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Catalog | name | Description | price |
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R-C-845 | PEI1.8K-19-fluorodecanoic acid | Perfluorodecanoic acid is an environmental pollutant,belonging to the perfluorochemical(PFCs)class of compounds.These compounds are widely used as surfactants,polymer and plastic additives,wetting agents,corrosion inhibitors, lubricants,foam-fire extinguishants,etc. | price> |
R-R-2545 | MZP-55 CAS No.2010159-48-3 | MZP-55/CAS No.2010159-48-3 is a PROTAC connected by ligands for von Hippel-Lindau and BRD3/4, with a Kd of 8 nM for Brd4BD2. | price> |
R-C-846 | Sulfo-Cy7 azide | A water-soluble NIR dye azide for Click Chemistry.Sulfo-Cyanine7 is a cyanine dye,an analog of Cy7® with improved photophysical properties.This dye is a perfect choice for NIR imaging studies in live organisms. | price> |
R-R-2546 | GSK761 | GSK761 is a selective inhibitor of speckled 140 kDa (SP140) with an IC50 value of 77.79 nM. GSK761 reduces monocyte-to-inflammatory macrophage differentiation and lipopolysaccharide (LPS)-induced inflammatory activation. GSK761 induces the production of CD206+ regulatory macrophages by inhibiting SP140. | price> |
R-C-847 | Cyanine3-vancomycin | Vancomycin is a glycopeptide antibiotic,which is used to treat many bacterial infections.It can inhibit the synthesis of bacterial cell wall,has strong effect on Staphylococcus aureus,Streptococcus pyogenes and Streptococcus pneumoniae, and also has good effect on Bacillus difficile,Bacillus anthracis and diphtheria. | price> |
R-R-2547 | ODM-207 CAS No.1801503-93-4 | ODM-207 (BET-IN-4)/CAS No.1801503-93-4 is a potent BET bromodomain protein (BRD4) inhibitor, with an IC50 of ≤ 1 μM. | price> |
R-C-848 | Alginate-Thiol | Alginate is mainly sodium alginate from brown algae(such as Laminaria)or soil bacteria(such as brown nitrogen fixing bacteria)Sodium alginate,a biodegradable hydrophilic polysaccharide,can be used as microspheres for drug delivery system. We can use FITC/rhodamine/Cy3/Cy5/cy7/ICG and other fluorescent dyes to label sodium alginate to make fluorescent microspheres for in vivo imaging.We can also modify alginate with amino,sulfhydryl,maleimide,activated lipid,biotin and azide,and couple polymers,antibodies,proteins,peptides or other small molecules with sodium alginate,which can be used in tumor targeting research or drug delivery research for different purposes. | price> |
R-R-2548 | Tz-Thalidomide CAS No.2087490-42-2 | Tz-Thalidomide/CAS No.2087490-42-2 is a tetrazine tagged Thalidomide (HY-14658) (Ligands for E3 Ligase). Tz-Thalidomide has binding affinity for BRD4, with IC50s of 46.25 μM (BRD4-1) and 62.55 μM (BRD4-2). Tz-Thalidomide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. | price> |
R-C-849 | BSA-AuNCs | At the excitation wavelength of 670nm and 520nm,aubsca-525 shows good emission. When FITC is used as a reference fluorophore,FITC/BSA auncs show good linear response in the temperature range of 1-71℃,and provide temperature independent spectral shift,temperature accuracy,activation energy and reusability.The high temperature induced fluorescence quenching of FITC/BSA auncs may be due to the weakening of Au-S bond,which reduces the charge transfer from BSA to auncs. | price> |
R-R-2549 | PBRM1-BD2-IN-8 CAS No.2819989-75-6 | PBRM1-BD2-IN-8 (compound 34)/CAS No.2819989-75-6 is a potent PBRM1 Bromodomain inhibitor (PBRM1-BD2 Kd=4.4 μM, PBRM1-BD2 IC50=0.16 μM; PBRM1-BD5 Kd=25 μM). PBRM1-BD2-IN-8 shows anti-cancer activity. | price> |
R-C-850 | DPA-PEG-DPA | Dopamine is the most abundant catecholamine neurotransmitter in the brain.It is a neurotransmitter,a chemical that helps cells deliver pulses.This kind of secretion in the brain is related to people lust and feeling,It conveys the information of excitement and happiness.Polyethylene glycol(PEG)is a polymer of ethylene oxide hydrolysatewhich is non-toxic and non irritating.It is widely used in various pharmaceutical preparations. | price> |
R-R-2550 | GSK4028 CAS No.2079886-19-2 | GSK4028/CAS No.2079886-19-2 is the enantiomeric negative control of GSK4027, which is a PCAF/GCN5 bromodomain chemical probe, the pIC50 of GSK4028 is 4.9 in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. | price> |
R-C-851 | MC (C5)-Val-Cit | MC(C5)-Val CIT is a kind of cleavable ADC linker,which can be used to synthesize antibody coupled drugs(ADC). | price> |
R-R-2551 | BRM/BRG1 ATP Inhibitor-2 CAS No.2368900-77-8 | BRM/BRG1 ATP Inhibitor-2/CAS No.2368900-77-8 is a BRG1/BRM ATPase inhibitor for the research of BAF-related disorders. | price> |
R-C-852 | Peptide-PEG2K-upconversion materia(NaGdF4:Yb,Er@NaGdF4) | The core-shell NaGdF4:Yb,Er@NaGdF4,nd upconversion nanoparticles(ucnps)were successfully prepared by polypeptide peg2k upconversion material coprecipitation method.The water solubility of ucnps was improved by ligand exchange reaction between nitrous groups of tetrafluoroborate. | price> |
R-R-2552 | PROTAC BRD4 Degrader-8 | PROTAC BRD4 Degrader-8 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4, with IC50s of 1.1 nM and 1.4 nM for BRD4 BD1 and BD2, respectively. PROTAC BRD4 Degrader-8 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells. | price> |
R-C-853 | FeCo-TCPP | TCPP(tris(1-chloro-2-propyl)phosphate)is a flame retardant commonly used in polyurethane foam in consumer products and in home insulation,and in electronics.It is used as an additive to polyurethane foam and is not chemically bound,and it escapes from products into the indoor environment. | price> |
R-R-2553 | LT052 CAS No.2543545-44-2 | LT052/CAS No.2543545-44-2 is a highly selective BET BD1 inhibitor with an IC50 of 87.7 nM. LT052 exhibits nanomolar BRD4 BD1 potency and 138-fold selectivity over BRD4 BD2 (IC50=12.130 μM). LT052 has anti-inflammatory activity and can be used for acute gout arthritis research. | price> |
R-C-854 | PGA100-NH2 | Polyglutamic acid(γ-PGA),also known as natto gum and polyglutamic acid,is a kind of water-solublebiodegradable,non-toxic biopolymer produced by microbial fermentation. | price> |
R-R-2554 | BETd-246 CAS No.2140289-17-2 | BETd-246/CAS No.2140289-17-2 is a second-generation and PROTAC-based BET bromodomain (BRD) inhibitor connected by ligands for Cereblon and BET, exhibiting superior selectivity, potency and antitumor activity. | price> |