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Catalog	name	Description	price
R-R-2595	GSK973 CAS No.2138473-38-6	GSK973/CAS No.2138473-38-6 is a highly selective, orally bioavailable inhibitor of the BD2s (second bromodomains) of the BET family, with a pIC50 of 7.8 and a pKd of 8.7 for BRD4 BD2. GSK973 displays a 1600-fold selectivity for BRD4 BD2 over BRD4 BD1. GSK973 shows good potency against BRD2 BD2, BRD3 BD2, and BRDT BD2 (pIC50=7.4~7.8; pKd=8.3~8.5).	price>
R-C-896	cRGD-PAE1K-SS-PEG2K-b-PCL4K	Arg Gly ASP is composed of arginine,glycine and aspartic acid.RGD cell binding sequences have been identified in other extracellular matrix proteins,including fibronectin and laminin.A family of membrane proteins called integrins act as receptors for these cell adhesion molecules through RGD motifs.	price>
R-R-2596	PROTAC BET degrader-2 CAS No.2093388-33-9	PROTAC BET degrader-2/CAS No.2093388-33-9 is a PROTAC connected by ligands for Cereblon and BET with an IC50 value of 9.6 nM in cell growth inhibition in the RS4;11 cells and capable of achieving tumor regression.	price>
R-R-2597	TP-238 hydrochloride CAS No.2415263-05-5	TP-238 hydrochloride/CAS No.2415263-05-5 is a potent and selective dual CECR2/BPTF probe with IC50 values of 30 nM and 350 nM, respectively. TP-238 hydrochloride also inhibits BRD9 with a pIC50 of 5.9 and is less active against other 338 kinases.	price>
R-C-898	Cy5.5-PEG5000-hydrazide	Cy5.5 peg hydrazide is a kind of nano active near infrared fluorescent dye with terminal hydrazide group(-NH2).Hydrazide is a carbonyl reaction functional group,which can react with aldehyde or ketone groups to form a stable hydrazone bond.The reaction of hydrazide and carbonyl group makes cy5.5 dye combine with polysaccharide,glycosylated protein,antibody and enzyme.Cy5.5peg dye is a bright near-infrared fluorescent dye with excitation/emission wavelengths of 675nm/ 694nm.The peg crosslinker between cy5.5 and hydrazide group has better water solubility,lower steric hindrance and higher stability.	price>
R-R-2598	CBP/p300-IN-20	CBP/p300-IN-20 is a potent and selective p300/CBP inhibitor, with a pIC50 of 10.1 for p300. CBP/p300-IN-20 can be used for the research of cancer.	price>
R-C-899	Cy5.5-PEG1000	Cyanine dyes are one of the most commonly used fluorescent dyes in near-infrared (NIR)fluorescent dyes.Compared with conventional visible dyes,cyanine dyes have significant advantages.The molar absorptivity of cyanine dyes is the highest among the fluorescent dyes.The absorption of Cy5 hydrazide,cy5.5 alkyne and cy7 NHS ester is very low in the near-infrared region.They are the most stable long wavelength dyes with the highest fluorescence intensity.Women provides special cross-linking products of fat soluble cyanine dyes,water-soluble cyanine dyes and polyethylene glycol,PEG terminal links with various conventional groups and special groups,and accepts high difficulty product customization services.	price>
R-R-2599	Naringenin triacetate CAS No.3682-04-0	Naringenin triacetate/CAS No.3682-04-0 is a flavonoid isolated from plant, exhibits a good binding affinity with multiple crystal structures of first bromodomain BRD4 (BRD4 BD1).	price>
R-C-900	Cy5.5-PEG2000	Cyanine dyes are one of the most commonly used fluorescent dyes in near-infrared (NIR)fluorescent dyes.Compared with conventional visible dyes,cyanine dyes have significant advantages.The molar absorptivity of cyanine dyes is the highest among the fluorescent dyes.The absorption of Cy5 hydrazide, cy5.5 alkyne and cy7 NHS ester is very low in the near-infrared region.They are the most stable long wavelength dyes with the highest fluorescence intensity.Women provides special cross-linking products of fat soluble cyanine dyes,water-soluble cyanine dyes and polyethylene glycol,PEG terminal links with various conventional groups and special groups,and accepts high difficulty product customization services.	price>
R-R-2600	Phoenixin-20 CAS No.1415039-77-8	Phoenixin-20 (PNX-20)/CAS No.1415039-77-8 is a bioactive peptide with hormone-like actions in vertebrates, and can stimulates hypothalamo-pituitary-gonadal hormones and regulate reproductive processes in mammals. Phoenixin-20 promotes neuronal mitochondrial biogenesis via CREB-PGC-1α pathway. Phoenixin-20 has anxiolytic effect.	price>
R-C-901	Cy5.5-PEG5000	Cyanine dyes are one of the most commonly used fluorescent dyes in near-infrared (NIR)fluorescent dyes.Compared with conventional visible dyes,cyanine dyes have significant advantages.The molar absorptivity of cyanine dyes is the highest among the fluorescent dyes.The absorption of Cy5 hydrazide, cy5.5 alkyne and cy7 NHS ester is very low in the near-infrared region.They are the most stable long wavelength dyes with the highest fluorescence intensity.Women provides special cross-linking products of fat soluble cyanine dyes,water-soluble cyanine dyes and polyethylene glycol,PEG terminal links with various conventional groups and special groups,and accepts high difficulty product customization services.	price>
R-R-2601	Luteolin 7-sulfate CAS No.56857-57-9	Luteolin 7-sulfate/CAS No.56857-57-9 is isolated from Phyllospadix iwatensis Makino, a marine plant. Luteolin 7-sulfate attenuates TYR gene expression through the intervention of a cAMP-responsive element binding protein (CREB)- and microphthalmia-associated transcription factor (MITF)-mediated signaling pathway, leading to the decreased melanin synthesis.	price>
R-C-902	Black phosphorus Nanocomposite	Black phosphorus(BP)is a kind of crystal with structure similar to graphene.It is an allotrope of phosphorus and can exist in nature stably.As a new type of two-dimensional nano material,black phosphorus nano sheet has attracted extensive attention in the field of biomedicine,such as disease treatment,drug carrier,clinical detection,due to its large specific surface area,good biocompatibility,excellent photothermal properties and so on.	price>
R-R-2602	IV-255	IV-255 is a selective small molecule inhibitor of the BRG1 bromodomain. IV-255 increases the extent of DNA damage induced by Temozolomide (HY-17364) and Bleomycin (HY-108345). IV-255 inhibits the invasiveness of GBM cells. IV-255 enhances Temozolomide-induced cell death and the apoptosis-inducing activity of Temozolomide.	price>
R-C-903	Plant carbon point customization	As a new kind of zero dimensional carbon based nano fluorescent materials, carbon dots have attracted much attention.Due to its simple preparation,low toxicity,biocompatibility,easy functionalization,photobleaching resistance and fluorescence tunability,carbon dots have shown great potential in the field of biology.	price>
R-R-2603	iBRD4-BD1 diTFA CAS No.2839318-20-4	iBRD4-BD1 diTFA/CAS No.2839318-20-4 is selective BRD4 bromodomain inhibitor. iBRD4-BD1 diTFA has inhibition activity for BRD4 bromodomain with an IC50 value of 12 nM. iBRD4-BD1 diTFA can be used for the research of inflammation and oncology.	price>
R-C-904	Fingolimod hydrochloride-biotin	Fingolimod Hydrochloride is the hydrochloride salt form of fingolimod,an orally available derivate of myriocin and sphingosine-1-phosphate receptor 1(S1PR1, S1P1)modulator,with potential anti-inflammatory and immunomodulating activities. Upon oral administration,fingolimod,as a structural analogue of sphingosine, selectively targets and binds to S1PR1 on lymphocytes and causes transient receptor activation followed by S1PR1 internalization and degradation.	price>
R-R-2604	ZEN-3219 CAS No.1952264-34-4	ZEN-3219/CAS No.1952264-34-4 is a BET inhibitor with IC50s of 0.48, 0.16 and 0.47 μM for BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2), respectively. ZEN-3219 can be used to form PROTACs to induce degradation of BRD4.	price>
R-C-905	FITC labeled 388 active substance	FITC fluorescein isothiocyanate is a commonly used method to label antibody. FITC is usually yellow,brown or brownish yellow powder or crystal with stable properties and can be stored for several years at low temperature.Under alkaline conditions,the carboamide bond of FITC can covalently bind with lysine amino group on antibody protein to form FITC protein conjugate,namely fluorescent antibody or fluorescent conjugate.	price>
R-R-2605	(+)-JQ-1-aldehyde CAS No.2634778-37-1	(+)-JQ-1-aldehyde/CAS No.2634778-37-1 is the aldehyde form of (+)-JQ1. (+)-JQ-1-aldehyde can be uesd as a precursor to synthesize PROTACs, which targets BET bromodomains.	price>

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