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R-C-906 Polyphyllin I-cy3 Cy3 dye is a bright orange fluorescent dye,which can use 532 nm laser spectral line and display through TRITC(tetramethyl rhodamine)filter.In addition to immunocytochemical applications,Cy3 dye is usually used to label nucleic acids. Paris polyphylla saponin I is characterized by high sensitivity,strong specificity and good repeatability.Due to its stable reagent,easy preservation, simple operation and objective result judgment,it has been widely used in various fields of immunology. price>
R-R-2606 OXFBD04 CAS No.2231747-03-6 OXFBD04/CAS No.2231747-03-6 is a potent and selective BRD4 inhibitor with an IC50 of 166 nM. OXFBD04 is a potent BET bromodomain ligand with additional modest affinity for the CREBBP bromodomain. OXFBD04 has anti-cancer activity. price>
R-C-907 DSPE-PVGLIG-PEG2K Sodium alginate was used as the matrix to modify the metalloproteinase sensitive peptide Pro-Va1l-Gly-Leu-Iso-Gly(PVGLIG),which promoted the maturation of dendritic cells in vitro,neither dissociated nor combined with sodium alginate chain,It shows low immunogenicity. price>
R-R-2607 Menin-MLL inhibitor-22 CAS No.2851841-61-5 Menin-MLL inhibitor-22 (compound C20)/CAS No.2851841-61-5 is an orally active inhibitor of the interaction between menin and mixed lineage leukemia (MLL) (IC50=7 nM). Menin-MLL inhibitor-22 binds menin protein and inhibits cancer cell growth (MV4 cells, IC50=0.3 μM). Menin is a putative tumor suppressor associated with multiple endocrine neoplasia type 1 (MEN-1 syndrome). price>
R-C-908 Stick shape Fe3O4(100nm) Fe3O4 has stable material properties,good compatibility with organisms,high strength and magnetism.In the aspect of targeted drug carrier,magnetic targeted nano drug carrier can directly reach the lesions through the effect of external magnetic field after loading the components of drugs,which can reduce the side effects of drugs on other organs and tissues,and improve the efficacy and enhance the therapeutic effect. price>
R-R-2608 PROTAC BRD4 Degrader-10 CAS No.2417370-49-9 PROTAC BRD4 Degrader-10 (compound 8b)/CAS No.2417370-49-9 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-10 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 1.3 nM and 18 nM, respectively. price>
R-C-909 Furan modified sodium alginate Sodium alginate is a by-product of extracting iodine and mannitol from kelp or Sargassum.Its molecule is composed of β-D-mannuronic acid (m) and α-L-guluronic acid(g)by(1→4)bonds.It is a natural polysaccharide with the stability,solubility,viscosity and safety required for pharmaceutical excipients. price>
R-R-2609 Bromodomain inhibitor-8 CAS No.1300031-70-2 Bromodomain inhibitor-8 (Intermediate 21)/CAS No.1300031-70-2 is a BET bromodomain inhibitor for treating autoimmune and inflammatory diseases. price>
R-C-910 Fe3O4-PEG-CY5.5 Fe3O4 is a compound with the chemical formula Fe3O4.It exists in nature in the form of magnetite.Fe3O4 contains Fe2+and Fe3+ions,sometimes written as FeO.Fe2O3,Fe3O4 is most widely used as a black pigment.Cyanine 5.5 is widely used not only as a biomarker,but also as a derivatization reagent for some small molecules.Cyanine 5.5 is a common near-infrared fluorescent dye. price>
R-R-2610 UNC1021 CAS No.1322591-19-4 UNC1021/CAS No.1322591-19-4 is a selective L3MBTL3 inhibitor with an IC50 of 0.048 μM. price>
R-C-911 Oleic acid coated scintillators Scintillator is a kind of material that can emit light after absorbing high-energy particles or rays.It plays a very important role in the field of radiation detection.It is usually processed into crystal in application,which is called scintillation crystal.Rare earth nanocrystalline scintillators are characterized by easy size control,colorless transparency,good dispersion and excellent afterglow performance. price>
R-R-2611 PROTAC BRD9 Degrader-6 CAS No.2676211-62-2 PROTAC BRD9 Degrader-6/CAS No.2676211-62-2 is a potent degrader of BRD9 (IC50=0.13 nM), can be used for research of BAF complex-related disorders. price>
R-C-912 Chitosan coated gold nanoparticles Nanoparticles are solid colloidal particles with the size of 10~1000 nm,which can be used as drug delivery carriers.Nano drug delivery system is a new drug carrier produced by nano drug delivery technology.It has the characteristics of targeting,controlled release and surface modifiability.It can effectively pass through the mucosal surface and transport into the systemic circulation. Chitosan has excellent biocompatibility and bioadhesion as a new drug carrier. price>
R-R-2612 Halofuginone CAS No.55837-20-2 Halofuginone (RU-19110)/CAS No.55837-20-2, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects. price>
R-C-913 Galactose-VK19 Galactose(CH2OH(Choh)4cho)is a kind of monosaccharide,which can be found in dairy products or sugar beet.Galactose is a monosaccharide composed of six carbons and one aldehyde group,which is classified as aldose and hexose.It often exists in the form of d-galactoside in brain and nerve tissues,and is also an important component of some glycoproteins.The monosaccharide absorbed most quickly in the intestine is galactose. price>
R-R-2613 SRI-011381 hydrochloride CAS No.2070014-88-7 SRI-011381 hydrochloride/CAS No.2070014-88-7 is an orally active TGF-β signaling agonist, exhibits neuroprotective effects. price>
R-C-914 PPS50-PEG44-Rosmarinic acid Pps-peg poly(propylene sulfide)-polyethylene glycol copolymerization can form self-assembled amphiphilic substances.Keto mercaptan has also been successfully used in gene delivery.Amphiphilic block copolymers based on hydrophobic polysulfide(PPS)and hydrophilic polyether(PEG)have been used for solubilization and dispersion of single-walled carbon nanotubes(SWNTs).Rosmarinic acid(Rosa) is a kind of water-soluble natural phenolic acid isolated from rosemary,which is a natural antioxidant with strong antioxidant activity.Its antioxidant activity is stronger than vitamin E,caffeic acid,chlorogenic acid,folic acid and so on.It helps to prevent cell damage caused by free radicals,thus reducing cancer and animal mortality Risk of pulse hardening. price>
R-R-2614 Trabedersen sodium Trabedersen sodium is an antisense oligodeoxynucleotide that specifically inhibits TGF-β2 (TGF-beta/Smad). Trabedersen sodium can be used for the study of malignant brain tumors and other solid tumors overexpressing TGF-β2, such as those of the skin, pancreas and colon. price>
R-C-915 Albumin nanoparticles encapsulated ICG ICG nanoprobes were prepared by albumin self-assembly method with adjustable particle size,good stability,biocompatibility and tumor targeting. price>
R-R-2615 SRI-011381 CAS No.1629138-41-5 SRI-011381/CAS No.1629138-41-5 is an orally active TGF-β signaling agonist, exhibits neuroprotective effects. price>