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Catalog	name	Description	price
R-C-916	QSY21-NHS	The amine reactive quencher QSY 21 succinimidyl ester has a broad and intense absorption 661 nm maxima but no fluorescence making it useful as an acceptor in fluorescence resonance energy transfer FRET applications.	price>
R-R-2616	Halofuginone hydrobromide CAS No.64924-67-0	Halofuginone (RU-19110) hydrobromid/CAS No.64924-67-0, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone hydrobromid is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone hydrobromid is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone hydrobromid has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects.	price>
R-C-917	Ce6-NHS	Ce6-NHS is a chlorophyll derivative that is photosensitive and capable of producing singlet oxygen when activated with light (typically in the red to near-infrared spectrum).Ce6-NHS exhibits strong absorbance and fluorescence which can be utilized in imaging.It can generate reactive oxygen species (ROS) upon light activation, making it suitable for photodynamic therapy applications to target cancer cells. Used in PDT for the treatment of various cancers, as well as in imaging and diagnostic applications due to its fluorescence properties. N-hydroxysuccinimide (NHS) Ester/NHS esters are often used in bioconjugation to attach compounds (like Ce6) to proteins, peptides, or other biomolecules without causing significant steric hindrance or denaturation.NHS esters are widely used in biochemistry and biotechnology for labeling proteins and other biomolecules.	price>
R-R-2617	Ponsegromab CAS No.2368950-15-4	Ponsegromab (PF 06946860)/CAS No.2368950-15-4 is a potent and selective humanized anti-GDF15 antibody inhibitor with anti-cachexia activity. Ponsegromab binds to GDF15 and prevents the binding of GDF15 to GFRAL, thereby blocking GDF15/GFRAL-mediated signaling. Ponsegromab can be used in the research of cancers.	price>
R-C-918	PLA10K-PBA	Conductive polymer composites(CPC)with different CB and PBA contents were prepared by using polylactic acid(PLA)as plasticizer and carbon black(CB)as conductive filler.FTIR analysis showed that there was interaction between PLA / PBA matrix and carbon black filler,and PBA could improve the interaction.The results of rheological properties show that carbon black can significantly improve the apparent viscosity and reduce the fluidity of the composites, while polyanilic acid has the opposite effect.	price>
R-R-2618	EMT inhibitor-1 CAS No.1638526-21-2	EMT inhibitor-1/CAS No.1638526-21-2 is an inhibitor of of Hippo, TGF-β, and Wnt signaling pathways with antitumor activities.	price>
R-C-919	Azithromycin limonamide tobramycin	Azithromycin(azithromycin)is a semi synthetic 15 membered macrolide antibiotic, which is used to treat bacterial infection.The mechanism of action of azithromycin is the same as that of erythromycin and other drugs.It also produces antibacterial effect by inhibiting bacterial protein synthesis. Tobramycin is an aminoglycoside antibiotic.It is used for urinary tract infections caused by Staphylococcus and gram-negative bacilli,such as pyelonephritis,cystitis,epididymitis,pelvic inflammatory disease,prostatitis, etc.respiratory tract infections,such as pneumonia,acute or chronic bronchitis,etc.ophthalmic preparations are used for the treatment of local infections of external eyes and appendages caused by sensitive bacteria.The three components all have antibacterial effect.	price>
R-R-2619	R-268712 CAS No.879487-87-3	R-268712/CAS No.879487-87-3 is an orally active and selective ALK-5 inhibitor, with an IC50 of 2.5 nM. R-268712 inhibits the phosphorylation of Smad3 in a dose-dependent manner with an IC50 of 10.4 nM. R-268712 suppresses glomerulonephritis as well as glomerulosclerosis by inhibiting TGF-β signaling, which can be used in studies of renal fibrosis and cancer.	price>
R-C-920	Pyropheophorbide a cas:24533-72-0	Pyropheophorbide a is a natural catabolite of ethylene-induced chlorophyll a degradation.Extracts of C.paradoxa contain pyropheophorbide a and significantly inhibit the growth of cancer cells in vitro.	price>
R-R-2620	Luspatercept CAS No.1373715-00-4	Luspatercept (ACE-536)/CAS No.1373715-00-4 is a recombinant modified ActRIIB fusion protein that binds with transforming growth factor β superfamily ligands. Luspatercept increases the erythrocyte numbers and promotes maturation of erythroid precursors. Luspatercept binds with GDF11 and inhibits Smad2/3 signaling. Luspatercept can be used for the research of anemia.	price>
R-C-921	Carboxylated Ti3C2 mxene quantum dots(30-60nm)	Mxene materials have attracted more and more attention in electrochemical energy storage applications,and mxene also has photoactivity on the scale of quantum dots,making it a substitute for solar energy conversion equipment.A Janus structure cobalt nanoparticles coupled Ti3C2 mxene quantum dots(CO mqd)Schottky catalyst with adjustable cobalt loading was demonstrated,which can be used as photoanode for Photoelectrochemical water oxidation.The introduction of cobalt can induce the surface plasmon effect and act as the oxidation center of water, so as to realize the visible light collection ability and improve the surface reaction kinetics.	price>
R-R-2621	Carotuximab CAS No.1268714-50-6	Carotuximab (TRC105)/CAS No.1268714-50-6 is a IgG1 monoclonal antibody that blocks endoglin (CD105) and its downstream Smad signaling pathway. Carotuximab has immunomodulatory and antineoplastic actions.	price>
R-C-922	Carboxylated Ti3C2 mxene quantum dots(Within 10nm)	Mxene materials have attracted more and more attention in electrochemical energy storage applications,and mxene also has photoactivity on the scale of quantum dots,making it a substitute for solar energy conversion equipment.A Janus structure cobalt nanoparticles coupled Ti3C2 mxene quantum dots (CO mqd) Schottky catalyst with adjustable cobalt loading was demonstrated,which can be used as photoanode for Photoelectrochemical water oxidation.The introduction of cobalt can induce the surface plasmon effect and act as the oxidation center of water,so as to realize the visible light collection ability and improve the surface reaction kinetics.	price>
R-R-2622	SIS3 free base CAS No.521985-36-4	SIS3 free base/CAS No.521985-36-4 is a potent and selective inhibitor of Smad3 phosphorylation. SIS3 free base inhibits the myofibroblast differentiation of fibroblasts by TGF-β1. SIS3 free base does not affect the phosphorylation of Smad2.	price>
R-C-923	Doxorubicin modified by carboxylated Ti3C2 mxene(Within 10nm)	Mxene materials have attracted more and more attention in electrochemical energy storage applications,and mxene also has photoactivity on the scale of quantum dots,making it a substitute for solar energy conversion equipment.A Janus structure cobalt nanoparticles coupled Ti3C2 mxene quantum dots(CO mqd) Schottky catalyst with adjustable cobalt loading was demonstrated,which can be used as photoanode for Photoelectrochemical water oxidation.The introduction of cobalt can induce the surface plasmon effect and act as the oxidation center of water, so as to realize the visible light collection ability and improve the surface reaction kinetics.Doxorubicin is an anti-tumor antibiotic,which can inhibit the synthesis of RNA and DNA.It has the strongest inhibitory effect on RNA and a wide range of anti-tumor spectrum.Doxorubicin has effects on a variety of tumors.It is a cycle nonspecific drug and has killing effect on tumor cells in various growth cycles.	price>
R-R-2623	Livmoniplimab CAS No.2412004-88-5	Livmoniplimab (ABBV-151; ARGX-115)/CAS No.2412004-88-5 is a potent, humanized monoclonal antibody against the LRRC32 (GARP)/TGFβ1 complex. Livmoniplimab blocks LRRC32-mediated latent TGFβ1 activation and release. Livmoniplimab has potential in cancer research as a single anticancer agent or in combination with an anti-PD-1 mAb to inhibit locally advanced or metastatic solid tumors (NCT03821935).	price>
R-C-924	Biotin rosin acid	Rosin acid is a kind of tricyclic diterpenoid oxygenated compound,which is one of the most important resin acids.Insoluble in water,soluble in general organic solvents and dilute sodium hydroxide solution,soluble in alcohol,benzene, chloroform,acetone,ether and carbon disulfide.Biotin is also known as vitamin H and coenzyme R.its main function is to act as coenzyme in decarboxylation carboxylation reaction and deamination reaction.It can transfer CO2 from one compound to another,so that one compound becomes another.	price>
R-R-2624	SJ000063181 CAS No.945189-68-4	SJ000063181/CAS No.945189-68-4 is a potent BMP signaling activator with an EC50 ≤1 µM. SJ000063181 can be used as chemical probes to interrogate BMP signaling due to it can penetrate zebrafish embryos.	price>
R-C-925	DOPE-PEG12-(KIAALKK)4-CONH2	1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(polyethylene glycol) has both hydrophilicity and hydrophobility and is the excellent liposome formation material that can be used for drug delivery,gene transfection and vaccine delivery as well.Moreover,these material can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies, peptides.	price>
R-R-2625	Trabedersen CAS No.925681-61-4	Trabedersen (AP 12009)/CAS No.925681-61-4 is an antisense oligodeoxynucleotide that specifically inhibits TGF-β2 (TGF-beta/Smad). Trabedersen can be used for the study of malignant brain tumors and other solid tumors overexpressing TGF-β2, such as those of the skin, pancreas and colon.	price>

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