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Catalog	name	Description	price
R-C-936	DOTA-TAT（YGRKKRRQRRR）	tetraazacyclo-dodecanetetra-acetic acid-TAT（YGRKKRRQRRR) microcyclic carrier core significantly enhances intraocular penetrance of multiple drugs.It carries the advantages of small size,targeted intracellular drug delivery and non-invasive monitoring of therapeutic agents.Intraocular delivery of anti-VEGF agents can be one of its immediate applications.	price>
R-R-2636	Hydrochlorothiazid-13C,d2 CAS No.1190006-03-1	Hydrochlorothiazid-13C,d2/CAS No.1190006-03-1 is the 13C- and deuterium labeled Hydrochlorothiazide. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect.	price>
R-C-937	Methyltetrazine-OH	(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.	price>
R-R-2637	Hydrochlorothiazide-13C6 CAS No.1261396-79-5	Hydrochlorothiazide-13C6/CAS No.1261396-79-5 is the 13C labeled Hydrochlorothiazide. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect.	price>
R-R-2638	10,11-Dehydrocurvularin CAS No.21178-57-4	10,11-Dehydrocurvularin/CAS No.21178-57-4 is a prevalent fungal phytotoxin and an antibiotic. 10,11-Dehydrocurvularin is a strong activator of the heat shock response. 10,11-Dehydrocurvularin inhibits TGF-β signalling pathway. Anti-tumorous activity.	price>
R-C-939	HCPT-NHS	Camptothecin is a plant anticancer drug,light yellow needle like crystal. Camptothecin has good curative effect on gastrointestinal tract and head and neck cancer,but it has side effect of urination in a few patients.The anticancer activity of 10 hydroxycamptothecin is higher than that of camptothecin.It also has obvious curative effect on liver cancer and head and neck cancer with less side effects.	price>
R-R-2639	(Rac)-Upacicalcet CAS No.2649575-19-7	(Rac)-Upacicalcet/CAS No.2649575-19-7 is the racemate of Upacicalcet.Upacicalcet is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT).	price>
R-C-940	PAMAM-COOH (G4)	Dendrimer with positive charge surface(g4-pamam-nh2)and dendrimer with neutral surface(g4-pamam-oh)can inhibit the activity of pepsin.At the same time,it was found that these dendrimers were used as part of the mixed noncompetitive pepsin inhibitors.There was no correlation between pepsin activity and protein CD profile.	price>
R-R-2640	Gadolinium chloride CAS No.10138-52-0	Gadolinium chloride is a specific calcium-sensing receptor (CaSR) agonist. Gadolinium chloride can be used for the research of cardiovascular disease.	price>
R-C-941	mPEG5K-b-PDPA17K	Block copolymer micelles are usually formed by self-assembly of amphiphilic block copolymers in aqueous media.Hydrophilic and hydrophobic blocks form shell and core micelles,respectively.Methoxypolyethylene glycol(MPEG)-b-Poly(2-diisopropylamino)ethyl methacrylate(PDPA)block copolymer was synthesized by atom transfer radical polymerization of 2-bromoisobutyl bromide and MPEG in the presence of triethylamine catalyst.Atom transfer radical polymerization of diisopropylethyl methacrylate (diisopropylethyl ethyl methacrylate) was carried out in DMF at 70℃ with artificial neural network(ANN) and N,pentamethyldiethylenetriamine-copper bromide catalyst system.The pH induced micellization-decellularization was studied by fluorescence method and pyrene probe.	price>
R-R-2641	Cinacalcet hydrochloride CAS No.364782-34-3	Cinacalcet hydrochloride (AMG-073 hydrochloride)/CAS No.364782-34-3 is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease treatment.	price>
R-C-942	Peptide modified hollow cus wrapped plasmid and cisplatin	Polypeptides have a significant structural advantage,that is,they can be synthesized by solid-phase synthesis or biosynthesis without affecting the original functional polypeptides.New functional polypeptides can be introduced into one or both ends of polypeptides to obtain multifunctional fusion peptides. Cisplatin is an anticancer drug containing platinum, which is orange or yellow crystalline powder,slightly soluble in water and easily soluble in dimethyl Formamide can be gradually converted into trans and hydrolyzed in aqueous solution.	price>
R-R-2642	Evocalcet CAS No.870964-67-3	Evocalcet (KHK7580)/CAS No.870964-67-3 is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism.	price>
R-C-943	Rhodamine B labeled calcium carbonate nanoparticles(100nm)	Rhodamine B is a synthetic chemical and a dye.It is often dissolved in water and used as a tracer dye to determine the speed and direction of water flow. Rhodamine dye is also widely used in fluorescence microscopy,flow cytometry, fluorescence related spectroscopy and enzyme-linked immunosorbent assay.Nano calcium carbonate is also called ultrafine calcium carbonate.The most mature application industry of nano calcium carbonate is plastic industry,which is mainly used in high-grade plastic products.	price>
R-R-2643	Calhex 231 hydrochloride CAS No.2387505-78-2	Calhex 231 hydrochloride/CAS No.2387505-78-2 is a CaSR inhibitor via negative allosteric modulation. Calhex 231 hydrochloride blocks Ca2+-induced accumulation of [3H]inositol phosphate with an IC50 of 0.39 μM in HEK293 cells. Calhex 231 hydrochloride has the potential for diabetic cardiomyopathy (DCM) treatment.	price>
R-C-944	DSPE-PEG2000-PPI	Pyrophosphate(PPI)is an anion with important biological functions,which participates in many energy conversion and metabolism processes in organisms. PPI is the product of hydrolysis of adenosine triphosphate in living cells,and its stable metabolic process ensures the normal operation of biological functions.Under the catalysis of DNA polymerase,PPI is closely related to DNA replication,genetic information processing and other processes.	price>
R-R-2644	NPS-2143 hydrochloride CAS No.324523-20-8	NPS-2143 hydrochloride (SB-262470A hydrochloride)/CAS No.324523-20-8, an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 hydrochloride (SB-262470A hydrochloride) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor.	price>
R-C-945	PLGA10K-PEG2K-Cys-Arg-Glu-Lys-Ala（CREKA）	Cys-Arg-Glu-Lys-Ala（CREKA)sequence has been identified as a tumor homing peptide,which can effectively bind to coagulation plasma protein.The results have been compared with the reported separation of CREKA(peptide without dye). It is found that fluorescein affects the energy distribution of the minimum energy conformation,and the repulsive spatial interaction produced by the dye shifts the energy distribution of the minimum energy conformation to a higher energy value.	price>
R-R-2645	Tecalcet Hydrochloride CAS No.177172-49-5	Tecalcet Hydrochloride (R 568 Hydrochloride)/CAS No.177172-49-5, an orally active calcimimetic compound, allosterically and positively modulates the calcium-sensing receptor (CaSR). Tecalcet Hydrochloride (R 568 Hydrochloride) increases the sensitivity to activation by extracellular Ca2+.	price>
R-C-946	Quercetin@IrSx-polyethylene glycol-Chlorin E6	Quercetin is a kind of flavonol which is widely distributed in the plant kingdom and has a variety of biological activities.Quercetin can resist free radicals, complex or capture free radicals,prevent lipid peroxidation; can directly inhibit tumor,effectively play the role of anti-cancer;it also has strong biological activity in antibacterial,anti-inflammatory,anti allergic,and prevention of diabetic complications.	price>

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