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R-R-2646 Ligustroflavone CAS No.260413-62-5 Ligustroflavone/CAS No.260413-62-5, extracted from Ligustrum lucidum, is a potential candidate as calcium-sensing receptor (CaSR) antagonist. Ligustroflavone exhibits protective effects against diabetic osteoporosis in mice. price>
R-C-947 Pyruvic acid-FITC Pyruvic acid, also known as a-oxopropanoic acid,is an organic compound with the chemical formula of c3h4o3 and the structure of ch3cocooh.It is an important intermediate in the sugar metabolism of all biological cells and the mutual transformation of many substances in the body.As a basic chemical raw material, pyruvic acid is widely used in various fields such as chemistry, pharmacy,food, agriculture and environmental protection because of its active ketone and carboxyl group.Fluorescein isothiocyanate(FITC)is a derivative of fluorescein, which is widely used in flow cytometry and other fields.FITC is reactive to nucleophiles including amines and sulfhydryls on proteins.The excitation and emission peak wavelength of FITC is about 495 nm/519 nm,which makes it green. Like most fluorescent dyes,it is prone to photobleaching. price>
R-R-2647 Upacicalcet sodium CAS No.2052969-18-1 Upacicalcet sodium/CAS No.2052969-18-1 is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT). price>
R-C-948 Mandelic acid-FITC Mandelic acid and its derivatives are metabolites of epinephrine and norepinephrine by monoamine oxidase and catecholamine-O-methyltransferase in vivo.There is a chiral carbon atom in mandelic acid molecule,so there are(R)and (s) enantiomers.Fluorescein isothiocyanate(FITC)is a derivative of fluorescein, which is widely used in flow cytometry and other fields.FITC is reactive to nucleophiles including amines and sulfhydryls on proteins.The excitation and emission peak wavelength of FITC is about 495 nm/519 nm,which makes it green. Like most fluorescent dyes,it is prone to photobleaching. price>
R-R-2648 Calcium-Sensing Receptor Antagonists I CAS No.478963-79-0 Calcium-Sensing Receptor Antagonists I/CAS No.478963-79-0 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. price>
R-C-949 Salicylic acid-FITC Salicylic acid is soluble in ethanol,ether,chloroform,benzene,acetone and turpentine,but not soluble in water.It exists in willow bark,white pearl leaves and Betula platyphylla.Salicylic acid is a kind of organic acid,which can be metabolized by salicin.It is widely used in organic synthesis and is also a plant hormone.Fluorescein isothiocyanate(FITC)is a derivative of fluorescein, which is widely used in flow cytometry and other fields.FITC is reactive to nucleophiles including amines and sulfhydryls on proteins.The excitation and emission peak wavelength of FITC is about 495 nm/519 nm,which makes it green. Like most fluorescent dyes,it is prone to photobleaching. price>
R-R-2649 SB-423562 CAS No.351490-27-2 SB-423562/CAS No.351490-27-2 is a short-acting calcium-sensing receptor (CaR) antagonist. SB-423562 has the potential for osteoporosis research. price>
R-C-950 p-SCN-BnNOTA The chelating agents except p-SCN-BnNOTA in plasma were very stable,and the dissociation rate of Cu2+was less than 9% at 96 H.The immune response varies with the choice of chelating agents,especially the antiserum of Cu2+nota KLH conjugate.Compared with other chelating agents,p-SCN-BnNOTA has a significant advantage in the preparation of antibody. price>
R-R-2650 GSK3004774 CAS No.2138814-32-9 GSK3004774/CAS No.2138814-32-9 is a potent, nonabsorbable agonist of CaSR, with an pEC50 of 7.3, 6.6 and 6.5 for human, mouse and rat CaSR, respectively. GSK3004774 shows an EC50 of 50 nM for human CaSR. price>
R-C-951 Gold magnetic particle(100nm) Gold magnetic nanoparticles are magnetic nanocomposite particles whose core is magnetic nanoparticles and whose surface is modified by gold nanoparticles.It is widely used in many fields,such as enzyme immobilization,biological separation, nucleic acid purification,tumor targeted drug delivery,immunological detection, tumor hyperthermia and so on.This product is a gold magnetic particle with particle size of 100nm,which is dispersed in water. price>
R-R-2651 Calindol hydrochloride CAS No.729610-18-8 Calindol hydrochloride/CAS No.729610-18-8 is a positive allosteric modulator (PAM) of calcimimetic calcium-sensing receptor (CaSR) with an EC50 of 132 nM. price>
R-C-952 Modification of red light carbon quantum dots by streptomycin affinity Quantum dots(QDs)are semiconductor nanocrystals of zero dimensional nanomaterials with the particle size of 1-10 nm.Streptavidin is a 60 kDa protein purified from Streptomyces avidin.Streptavidin homotetramer has high affinity for biotin(vitamin B7). price>
R-R-2652 AC-265347 CAS No.1253901-26-6 AC-265347/CAS No.1253901-26-6 is a calcium-sensing receptor (CaSR) agonist and positive allosteric modulator (ago-PAM) with the functional affinity (pKB) of 5.1. AC-265347 can be used for the research of hyperparathyroidism and related diseases. price>
R-C-953 FITC-HWYGYT We sell research products related to nano targeted drug delivery system, including synthetic phospholipids,polyethylene glycol derivatives,block copolymers,gold nanoparticles,magnetic nanoparticles and fluorescent dyes.We can also provide special customized products. price>
R-R-2653 L-Glutamine-13C5 CAS No.184161-19-1 L-Glutamine-13C5/CAS No.184161-19-1 is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells. price>
R-C-954 DSPE-PEG2000-Serinol Serinol is a kind of pharmaceutical intermediate,which is the main raw material for the synthesis of iodofol.As a kind of non-ionic contrast agent,iodofol has been widely used in developed countries as a diagnostic reagent for blood system,lymphatic system,urinary system and nervous system. price>
R-R-2654 LY341495 CAS No.201943-63-7 LY341495/CAS No.201943-63-7 is a metabotropic glutamate receptor (mGluR) antagonist with IC50s of 21 nM, 14 nM, 7.8 μM, 8.2 μM, 170 nM, 990 nM, 22 μM for mGlu2, mGlu3, mGlu1a, mGlu5a, mGlu8, mGlu7, and mGlu4 receptors, respectively. price>
R-C-955 PEG114-PAEMA70 The PHE responsive anionic polymer is a block copolymer of poly(ethylene glycol)(PEG)and poly(2-aminoethyl methacrylate)(paema) modified by 2,3-dimethylmaleic anhydride(PPD).The coating polymer was mixed with a small amount of PEG paema (denoted as PPS)modified with succinic anhydride to obtain a balanced negative charge and PEG shielding surface with Phe response characteristics,so as to achieve the expected tumor triggering and enhanced gene delivery. price>
R-R-2655 Ro 67-7476 CAS No.298690-60-5 Ro 67-7476/CAS No.298690-60-5 is a potent positive allosteric modulator of mGluR1 and potentiates glutamate-induced calcium release in HEK293 cells expressing rat mGluR1a with an EC50 of 60.1 nM. Ro 67-7476 is a potent P-ERK1/2 agonist and activates ERK1/2 phosphorylation in the absence of exogenously added glutamate (EC50=163.3 nM). price>
R-C-956 Tannic acid and manganese coated black phosphorus quantum dots The cation is combined with the black phosphorus quantum dots by electrostatic force,which greatly improves the antioxidant capacity.Polyethylene glycol or polyethylene glycol derivative is combined with the black phosphorus quantum dots by van der Waals force,so that the black phosphorus quantum dots can be stably dispersed in water.Tannic acid is the common name of polyphenol organic compound family,also known as hydrolyzable tannin.Tannic acid is a high molecular weight polyphenol,which is formed by esterification of gallic acid and 3-gallic acid gallic acid with glucose. price>