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R-R-2656 Eglumegad hydrochloride Eglumegad (LY354740) hydrochloride is a highly potent and selective group II (mGlu2/3) receptor agonist with IC50s of 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively. Eglumegad hydrochloride protects neurons from NMDA toxicity. Eglumegad hydrochloride has anxiolytic- and antipsychotic-like effects. price>
R-C-957 Titanium dioxide coated ferric oxide(50nm) The preparation method of carbon fiber materials loaded with titanium dioxide nano film and Fe3O4 nanoparticles,using titanium butyrate as precursor,natural cellulose as template,titanium dioxide nano film deposited on the template surface by surface sol gel method,soaked in ferric chloride aqueous solution, and finally dried and calcined to obtain the supported titanium dioxide nano film and four oxygen.Four It is a kind of carbon fiber material based on ferroferric nanoparticles. price>
R-R-2657 MPEP Hydrochloride CAS No.219911-35-0 MPEP Hydrochloride/CAS No.219911-35-0 is a potent, selective, noncompetitive, orally active and systemically active mGlu5 receptor antagonist, with an IC50 of 36 nM for completely inhibiting quisqualate-stimulated phosphoinositide (PI) hydrolysis. MPEP Hydrochloride has anxiolytic-or antidepressant-like effects. MPEP (Hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. price>
R-C-958 Dextran-EDA-Phenylboronic acid Phenylboronic acid(contains varying amounts of Anhydride)(98-80-6);Phenylboronic acid(contains varying amounts of Anhydride):(98-80-6) used for scientific research and chemical synthesis intermediates.Dextran is a homo polysaccharide composed of glucose as monosaccharide,and the glucose units are connected by glycoside bonds.According to the type of glycoside bond,alpha glucan and beta glucan can be divided into two groups. price>
R-R-2658 MTEP hydrochloride CAS No.1186195-60-7 MTEP hydrochloride/CAS No.1186195-60-7 is a potent, non-competitive and highly selective mGluR5 antagonist, with an IC50 of 5 nM and a Ki of 16 nM. MTEP hydrochloride shows antidepressant and anxiolytic-like effects. price>
R-C-959 Melatonin encapsulated in sp94 peptide liposome The mechanism of sp94 is through increasing apoptosis and inhibiting angiogenesis,Sp94(sfsiihtpilpl)can specifically bind to hepatoma cells,and has important clinical application by increasing apoptosis and inhibiting tumor angiogenesis.It can be used for systematic treatment of patients with early hepatoma.Melatonin(MT)is one of the hormones secreted by the pineal gland.The secretion of melatonin has obvious circadian rhythm,which is inhibited during the day and active at night. price>
R-R-2659 (RS)-MCPG CAS No.146669-29-6 (RS)-MCPG (alpha-MCPG)/CAS No.146669-29-6 is a competitive and selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. (RS)-MCPG blocks theta-burst stimulation (TBS)-induced shifts in both juvenile and neonatal rat hippocampal neurons. price>
R-C-960 Liposome encapsulated melatonin Liposomes are hollow liposomes made from lecithin and ceramide.They have the same bilayer structure as the skin cell membrane structure and have excellent moisturizing effect on the skin,especially the liposomes coated with moisturizing substances such as hyaluronic acid and polyglucoside.Melatonin(MT) is one of the hormones secreted by the pineal gland One.The secretion of melatonin has obvious circadian rhythm,which is inhibited during the day and active at night. price>
R-R-2660 JNJ16259685 CAS No.409345-29-5 JNJ16259685/CAS No.409345-29-5 is a selective antagonist of mGlu1 receptor, and inhibits the synaptic activation of mGlu1 in a concentration-dependent manner with IC50 of 19 nM. price>
R-C-961 Encapsulation of paeonol with sp94 peptide liposome Sp94(sfsiihtpilpl)can specifically bind with hepatoma cells.It has important clinical application by increasing apoptosis of hepatoma cells and inhibiting tumor angiogenesis.It can be used for systematic treatment of patients with early hepatoma.Paeonol has analgesic,anti-inflammatory,antipyretic and antiallergic effects.It has sedative,hypnotic,antibacterial,anti-inflammatory, antioxidant and antihypertensive effects,In the aspect of daily chemical, paeonol can inhibit the production of O2 free radicals in cells,whiten the skin, reduce the pigmentation in the skin,and remove stasis and spots;at the same time,it also has anti-inflammatory,anti swelling and analgesic,anti allergic and anti-virus effects. price>
R-R-2661 LY367385 hydrochloride CAS No.2829282-00-8 LY367385 hydrochloride/CAS No.2829282-00-8 is a highly selective and potent mGluR1a antagonist. LY367385 hydrochloride has an IC50 of 8.8 μM for inhibiting of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with >100 μM for mGlu5a. LY367385 hydrochloride has neuroprotective, anticonvulsant and antiepileptic effects. price>
R-C-962 Liposome loaded with paeonol Liposomes are liposomes(hollow)made from lecithin and ceramide.They have the same bilayer structure as skin cell membrane and have excellent moisturizing effect on skin.Especially,liposomes coated with moisturizing substances such as hyaluronic acid and polyglucoside are more excellent moisturizing substances, Paeonol can inhibit the production of O2-free radicals in cells,whiten the skin, reduce the pigmentation in the skin,and remove stasis and spots;at the same time,it also has anti-inflammatory,anti swelling,analgesic,anti allergic and anti-virus effects. price>
R-R-2662 LY2794193 CAS No.2173037-97-1 LY2794193/CAS No.2173037-97-1 is a highly potent and selective mGlu3 receptor agonist (hmGlu3 Ki=0.927 nM,EC50=0.47 nM; hmGlu2 Ki=412 nM,EC50=47.5 nM). price>
R-C-963 Inclusion of nucleic acid in sp94 peptide liposomes Sp94(sfsiihtpilpl)can specifically bind with hepatoma cells,and has important clinical application by increasing apoptosis and inhibiting tumor angiogenesis. It can be used for systematic treatment of patients with early hepatoma.Nucleic acid is a kind of biopolymer,which is an essential component of all known life forms and the most important substance in all biomolecules In all animal and plant cells,microbial body. price>
R-R-2663 LY404039 CAS No.635318-11-5 LY404039/CAS No.635318-11-5 is a potent, selective and orally active mGluR2 and mGluR3 agonist with Kis of 149 nM and 92 nM for recombinant human mGluR2 and mGluR3, respectively. LY404039 shows >100-fold selectivity for mGluR2/3 over other receptors/transproters. LY404039 has antipsychotic and anxiolytic effects. price>
R-C-964 Liposome containing nucleic acid Liposomes are hollow liposomes made from lecithin and ceramide.They have the same bilayer structure as skin cell membrane and have excellent moisturizing effect on skin.Especially,liposomes coated with moisturizing substances such as hyaluronic acid and polyglucoside are more excellent moisturizing substances. Nucleic acid is a kind of biopolymer,which is essential for all known life forms The indispensable component is the most important substance in all biological molecules,which widely exists in all animal and plant cells and microorganisms. price>
R-R-2664 (S)-MCPG CAS No.150145-89-4 (S)-MCPG ((+)-MCPG)/CAS No.150145-89-4 is a potent group I/II metabotropic glutamate receptor (mGluRs) antagonist and the active isomer of (RS)-MCPG (HY-100371). (S)-MCPG can be used for the study of the function of mGluRs in spatial learning. price>
R-C-965 Polyamindoamine G5-polyethylene glycol-Vancomycin Polyamide amine dendrimer(PAMAM)is a kind of highly branched and symmetrical nano scale polymer compound.The cavity inside the molecule can be used to encapsulate drug molecules,and the terminal group can be modified to connect ligands,antibodies and other bioactive substances.The high density positive charge of the molecule can compress DNA.The molecular weight of 2K and 5K MPEG SC was used to bind G5 PAMAM was modified with two kinds of amino groups.The number of PEG with low degree of substitution was 13,and that with high degree of substitution was 51,which was 10% and 40% of the amino groups on the surface of g5pamam,respectively.Vancomycin(Van)is a kind of glycopeptide antibiotics. Its binding ability with target bacteria is equal to that of antigen antibody. It has the advantages of good stability,easy preparation and preservation. price>
R-R-2665 MMPIP hydrochloride CAS No.1215566-78-1 MMPIP hydrochloride/CAS No.1215566-78-1 is an allosteric metabotropic glutamate receptor 7 (mGluR7) selective antagonist (KB values 24 -30 nM). MMPIP hydrochloride acts as a pharmacological tool for elucidating the roles of mGluR7 on central nervous system functions. MMPIP hydrochloride alleviates pain and normalizes affective and cognitive behavior in neuropathic mice. price>
R-C-966 MS275-CY5.5 MS-275 is a histone deacetylase inhibitor that has shown potent and unique anticancer activity in preclinical models.The aims of this phase I trial were to determine the dose-limiting toxicities and maximum tolerated dose of oral MS-275 in humans administered with food on a once weekly schedule and to study the pharmacokinetics of oral MS-275. price>