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Catalog	name	Description	price
R-C-1124	PF06447475 CAS:1527473-33-1	PF06447475 is a highly potent,selective,brain penetrant,and in vivo active LRRK2 kinase inhibitor.Leucine rich repeat kinase 2(LRRK2)has been genetically linked to Parkinson disease(PD)by genome-wide association studies(GWAS).The most common LRRK2 mutation,G2019S,which is relatively rare in the total population,gives rise to increased kinase activity.As such,LRRK2 kinase inhibitors are potentially useful in the treatment of PD.	price>
R-C-2824	Yeast glucan-PEI25K-FITC	Yeast glucan is a polysaccharide with immune enhancing activity in yeast cell wall β- Dextran.β- Glucan widely exists in various fungi and plants,such as yeast,Lentinus edodes,Ganoderma lucidum and oats.It is the main functional substance for them to play a role in health care.Schiff base mainly refers to a class of organic compounds containing imine or methylimine characteristic groups(-RC=n-).Usually,Schiff base is formed by condensation of amine and active carbonyl It has excellent liquid crystal properties.Used as organic synthetic reagent and liquid crystal material.	price>
R-R-2824	LGD-6972 CAS No.1207989-09-0	LGD-6972/CAS No.1207989-09-0 is a selective and orally active glucagon receptor antagonist. LGD-6972 has the potential for type 2 diabetes research.	price>
R-C-1125	SP2509 CAS:1423715-09-6	Soluble in DMSO.LSD1 is a promising target for cancer therapy.Epigenetic control of histone methylation is frequently associated with oncogenesis and LSD1 is overexpressed in many types of cancer.siRNA knockdown of LSD1 has been shown to suppress growth of cancer cells.SP-2528 is a selective and reversible LSD1 inhibitor with an IC(50)of 10nM.SP-2528 demonstrates a high specificity for LSD1,with no effect on MAOi.Target:LSD1.	price>
R-C-2825	DSPE-PEG2000-MMP9	MMP9 protein;Selection of fusion label of matrix metalloproteinase 9(MMP9) recombinant protein:affinity label:the fusion expression of affinity label plays two roles in the process of protein recombinant expression:on the one hand,it is to make the process of protein purification easier;On the other hand,it is to promote the solubility of some insoluble proteins.	price>
R-R-2825	NNC-0640 CAS No.307986-98-7	NNC-0640/CAS No.307986-98-7 is a potent human G-protein-coupled glucagon receptor (GCGR) negative allosteric modulator (NAM) with an IC50 of 69.2 nM.	price>
R-C-1126	Molidustat(BAY85-3934) CAS:1154028-82-6	Molidustat,also known as BAY 85-3934,is a novel inhibitor of hypoxia-inducible factor(HIF)prolyl hydroxylase(PH)which stimulates erythropoietin(EPO)production and the formation of red blood cells.Phase I data have shown that inhibition of HIF-PH by Molidustat results in an increase in endogenous production of EPO.	price>
R-C-2826	DSPE-PEG1K-L-thyroxine	Thyroid stimulating hormone(TSH)is a hormone synthesized and secreted by the pituitary gland.It functions by binding with thyroid stimulating hormone receptor(TSHR).PEG lipid conjugate DSPE peg is not only widely used as a self-assembly material for anticancer drug delivery,but also as an additive material for surface functionalization of various drug delivery systems.	price>
R-R-2826	Lixisenatide acetate CAS No.1997361-87-1	Lixisenatide acetate/CAS No.1997361-87-1 is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes mellitus (T2DM).	price>
R-C-1127	KPT 9274 ( ATG-019) CAS:1643913-93-2	KPT-9274,also known as PAK4-IN-1,is a potent,selective and dual PAK4/NAMPT inhibitor.KPT-9274 interferences with PAK4/NAMPT signaling pathways, which results in reduction of G2-M transit as well as induction of apoptosis and decrease in cell invasion and migration in several human RCC cell lines. Mechanistic studies demonstrate that inhibition of the PAK4 pathway by KPT-9274 attenuates nuclear β-catenin as well as the Wnt/β-catenin targets cyclin D1 and c-Myc.	price>
R-C-2827	DSPE-PEG1K-3,5-Diiodo-DL-tyrosine	PEG lipid conjugate DSPE peg is not only widely used as a self-assembly material for anticancer drug delivery,but also as an additive material for surface functionalization of various drug delivery systems.Dl-3,5-diiodine tyrosine is flake crystal.Decompose at about 200 ℃.Solubility in water: 0.149g/l at 0 ℃,0.340g/l at 25 ℃ and 0.773g/l at 50 ℃. Soluble in dilute alkali.	price>
R-R-2827	GLP-1 moiety from Dulaglutide CAS No.1197810-60-8	GLP-1 moiety from Dulaglutide/CAS No.1197810-60-8 is a 31-amino acid fragment of Dulaglutide which is a glucagon-like peptide 1 receptor (GLP-1) agonist, extracted from patent US 20160369010 A1.	price>
R-C-1128	SAR191801 CAS:1234708-04-3	SAR191801 is a hPGDS inhibitor ,with IC50 of 12 nM in the Fluorescence Polarization Assay or the EIA assay.	price>
R-C-2828	PLGA-PEG-Hyaluronate	Hyaluronic acid is a kind of high molecular polymer.It is an advanced polysaccharide composed of unit D-glucuronic acid and N-acetylglucosamine. Between D-glucuronic acid and N-acetylglucosamine β- 1,3-glycosylation bond is connected, and the disaccharide units are connected by β- 1, 4-glycosylation bond.PLGA-PEG is one of the most commonly used biodegradable ABC polymers for drug delivery.Biotin can bind to avidin and streptavidin with high specificity and affinity.	price>
R-R-2828	GLP-1R agonist 2 CAS No.281209-71-0	GLP-1R agonist 2 (compound 2)/CAS No.281209-71-0 is a potent GLP-1R agonist. GLP-1R agonist 2 has the potential for the research of metabolic diseases like Type2 Diabetes and Obesity.	price>
R-C-1129	Baricitinib(LY3009104) CAS :1187594-09-7	Baricitinib(LY3009104,INCB028050)is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM in cell-free assays,~70 and ~10-fold selective versus JAK3 and Tyk2,no inhibition to c-Met and Chk2.	price>
R-C-2829	DSPE-PEG2K-CGSPGWVRC-FITC	Targeted polypeptide is a promising delivery ligand with the advantages of good permeability,convenient synthesis,low immunogenicity,low cost and easy modification.Cgspgwvrc is a lung endothelial cell targeted peptide(let) obtained by phage display technology, and its good lung endothelial cell targeting ability has been confirmed by experiments in vitro and in vivo.PEG lipid conjugate DSPE peg is not only widely used as a self-assembly material for anticancer drug delivery,but also as an additive material for surface functionalization of various drug delivery systems.	price>
R-R-2829	Survodutide CAS No.2805997-46-8	Survodutide (BI 456906)/CAS No.2805997-46-8 is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake.	price>
R-C-1130	TAK063 CAS:1238697-26-1	TAK-063,also known as Balipodect.,is a highly potent,selective,and orally active phosphodiesterase 10A(PDE10A)inhibitor.TAK-063 is currently being evaluated in clinical trials for the treatment of schizophrenia.Phosphodiesterase 10A(PDE10A)is a cAMP/cGMP phosphodiesterase highly expressed in medium spiny neurons(MSNs)in the striatum.TAK-063 represents a promising drug for the treatment of schizophrenia with potential for superior safety and tolerability profiles.	price>
R-C-2830	Oil soluble MnxFe3-xO4 nanoparticles	The average autocatalytic reaction order of MnxFe3-xO4 nanoparticles increased from 0.48 of pure epoxy to 0.52 of epoxy/MnxFe3-xO4 nanocomposites, because the hydroxyl groups on the surface of nanoparticles participated in the ring opening of epoxides.	price>

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