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R-R-2837 GLP-1(7-36), amide TFA GLP-1(7-36), amide TFA is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells. price>
R-C-1138 RO-3306 CAS:872573-93-8 RO-3306 has been shown to inhibit CDK1/cyclin B1 and CDK1/cyclin A.RO-3306 reversibly arrests human cells at the G2/M border of the cell cycle.RO-3306 allows for effective cell synchronization in early mitosis. price>
R-C-2838 PAMAM-NH2 generation 5 PAMAM dendrimer dendrimer surfactant.Dendrimer is a kind of flocculant in wastewater treatment.It has the advantages of low dosage,high decolorization rate,simple operation,secondary use of treated water and so on;Partial decolorization can reach 98% and COD removal rate can reach 96%. price>
R-R-2838 Dapiglutide CAS No.2296814-85-0 Dapiglutide (ZP7570)/CAS No.2296814-85-0 is a long-acting glucagon-like peptide-1 receptor 1R (GLP-1R)/Glucagon-like peptide-2 receptor (GLP-2R) dual agonist. Dapiglutide can be used for short bowel syndrome (SBS) research. price>
R-C-1139 Sibofimloc(VRT-1353385)CAS:1616113-45-1 Sibofimloc,also known as VRT-1353385 and Antibiotic-202,is an Escherichia coli fimbrial(FimH)adhesin inhibitor. price>
R-C-2839 DSPE-PEG-PLGLAG(TIMP) 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[(polyethylene glycol)-methoxy](sodium salt)is a PEG-modified lipids.It is a long circulating liposome membrane,formation of micelles in water dispersion,the critical micelle concentration(CMC)ratio of surfactant is 102 times lower,so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors. Suitable for the development of long circulating liposomes. price>
R-R-2839 Taspoglutide CAS No.275371-94-3 Taspoglutide/CAS No.275371-94-3 is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist developed for treatment of type 2 diabetes, with an EC50 value of 0.06 nM. price>
R-C-1140 GKT137831 CAS:1218942-37-0 GKT137831,a novel pyrazolopyridinedione derivative,a dual inhibitor of NADPH oxidases(NOX)1 and NOX4,reduces inflammation in the ischemic retina by dampening the pro-inflammatory phenotype of retinal immune cells as well as macroglial Müller cells and neurons.GKT137831 may be of significant benefit for patients with systemic sclerosis as studies in experimental models show that the compound may reduce the abnormal growth of connective tissue(fibrosis)and improve survival.GKT-137831 acts as a Nox4 and Nox1 inhibitor((Ki100-150 nM).GKT-137831 attenuates hypoxia-induced pulmonary vascular cell proliferation.Also a potent inhibitor of fibrosis and hepatocyte apoptosis. price>
R-C-2840 PLL-Metronidazole α- Polylysine is commonly used to coat tissue culture vessels as an adhesion factor to improve cell adhesion.This phenomenon is based on the interaction between positively charged polymers and negatively charged cells or proteins. price>
R-R-2840 Glucagon receptor antagonists-2 CAS No.202917-18-8 Glucagon receptor antagonists-2/CAS No.202917-18-8 is a highly potent glucagon receptor antagonist. price>
R-C-1141 CL-387785 (EKI-785) CAS :194423-06-8 CL-387785,also known as EKI-785,is a n irreversible inhibitor of EGF-receptor (EGFR)kinase activity in vivo(IC50=250-490 pM).CL-387785 covalently bound to EGF-R.It also specifically inhibited kinase activity of the protein(IC50 =370+/-120 pM),blocked EGF-stimulated autophosphorylation of the receptor in cells(ic50 approximately 5 nM),inhibited cell proliferation(IC50=31-125nM) primarily in a cytostatic manner in cell lines that overexpress EGF-R or c-erbB-2,and profoundly blocked the growth of a tumor that overexpresses EGF-R in nude mice(when given orally at 80 mg/kg/day for 10 days,daily). price>
R-C-2841 mPEG-PDLLA-PLL Methoxy poly(ethylene glycol)-poly(L-lactide)-poly(L-lysine)polyethylene glycol polylactic acid polylysine triblock,three polymer materials are crosslinked to form triblock copolymer α-Polylysine is commonly used to coat tissue culture vessels as an adhesion factor to improve cell adhesion.This phenomenon is based on the interaction between positively charged polymers and negatively charged cells or proteins. price>
R-R-2841 GLP-1R modulator L7-028 CAS No.2648317-95-5 GLP-1R modulator L7-028/CAS No.2648317-95-5 is an allosteric modulator enhancing GLP-1 binding to GLP-1R via a transmembrane site (EC50 11.01 ± 2.73 μM). price>
R-C-1142 GW2580 CAS:870483-87-7 GW2580 is an orally bioavailable and selective inhibitor of c-Fms kinase which completely inhibits human cFMS kinase in vitro at 0.06 μM.GW2580 acts as a competitive inhibitor of ATP binding to the cFMS kinase and inhibits colony-stimulating-factor-1 signaling. price>
R-C-2842 DSPE-TK-Decitabine As a specific DNA methyltransferase inhibitor,decitabine can reverse the DNA methylation process,induce tumor cells to differentiate into normal cells or induce tumor cell apoptosis. price>
R-R-2842 GLP-1R modulator C16 CAS No.875005-43-9 GLP-1R modulator C16/CAS No.875005-43-9 is an allosteric modulator enhancing GLP-1 binding to GLP-1R via a transmembrane site (EC50 8.43 ± 3.82 μM). price>
R-C-1143 TRX818 CAS:1256037-58-7 TRX-818 is a new,potent and multi-targeted anti-cancer agent in numerous human cancer cell lines. price>
R-C-2843 DSPE-PEG2K-PBA 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol is a PEG-modified lipids.It is a long circulating liposome membrane,formation of micelles in water dispersion,the critical micelle concentration(CMC)ratio of surfactant is 102 times lower, so the drug stability is better, even by hemodilution, can maintain the integrity of the micelle particle,has certain targeting, easy accumulation in solid tumors.Suitable for the development of long circulating liposomes.Benzeneboronic acid was used as boric acid component in Suzuki diaryl cross coupling study;Used for still and Suzuki cross coupling reaction price>
R-R-2843 GLP-1 receptor agonist 2 CAS No.2230197-64-3 GLP-1 receptor agonist 2/CAS No.2230197-64-3 is a glucagon-like peptide-1 receptor (GLP-1R) agonist. price>
R-C-1144 URMC-099 CAS:1229582-33-5 URMC-099 is an orally bioavailable,brain penetrant mixed lineage kinase (MLK)inhibitor with IC50 of 19 nM,42 nM,14 nM,and 150 nM,for MLK1,MLK2,MLK3,and DLK,respectively,and also inhibits LRRK2 activity with IC50 of 11 nM.URMC-099 also inhibits ABL1 with IC50 of 6.8 nM.URMC-099 induces autophagy. price>