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R-R-2862 {Val1}-Exendin-3/4 {Val1}-Exendin-3/4 is the first N-terminal 1-28 residues of Exendin-4 peptide. price>
R-C-1163 OPC 21268 CAS:131631-89-5 OPC21268 is a non-peptide AVP Receptor V(Vasopressin Receptor)antagonist that shows 1000-fold selectivity for V1 receptors over V2 receptors. price>
R-R-2863 (1R,5S,6S)-Tert-butyl CAS No.:273206-92-1 6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate CAS No.:273206-92-1 The mode of action of (1R,5S,6S)-Tert-butyl 6-amino-3-azabicyclo[31It is known that the compound is synthesized via a palladium-catalyzed cyclopropanation of maleimides with n-tosylhydrazones . The interaction of this compound with its potential targets and the resulting changes are subjects of ongoing research. price>
R-C-1164 GW9662 CAS: 22978-25-2 GW9662 is a potent and selective PPARγ antagonist with an IC50 of 3.3 nM, showing 10 and 1000-fold selectivity over PPARα and PPARδ,respectively. price>
R-R-2864 GLP-1 (1-36) amide (human, rat) (TFA) GLP-1 (1-36) amide (human, rat) (Glucagon-like Peptide 1 (1-36) amide (human, rat) ) TFA is a molecular variant of glucagon-like peptide 1 (GLP-1)-(7-36) amide. GLP-1 (1-36) amide (human, rat) TFA can stimulate [14C]aminopyrine accumulation on enzymatically dispersed enriched rat parietal cells. price>
R-C-1165 Coelenterazine H CAS:50909-86-9 Coelenterazine h is a derivative of Coelenterazine.Coelenterazine h is more sensitive to Ca2+than is the native complex,thus providing a valuable tool for measuring small changes in Ca2+concentrations. price>
R-R-2865 SAR441255 TFA SAR441255 TFA is a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist. SAR441255 TFA displays high potency with balanced activation of all three target receptors.?SAR441255 TFA shows positive acute glucoregulatory effectss in diabetic obese monkeys. price>
R-C-1166 AI-10-49 CAS:1256094-72-0 AI-10-49 is a protein-protein interaction inhibitor that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1 with a FRET IC50 of 0.26 uM. price>
R-R-2866 V-0219 CAS No.878453-71-5 V-0219 (Compound 9)/CAS No.878453-71-5 is an orally active, positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R). V-0219 can be used for obesity-associated diabetes research. price>
R-C-1167 Tideglusib (NP031112, NP-12) CAS:865854-05-3 Tideglusib(NP031112)is an irreversible GSK-3 inhibitor with IC50s of 5 nM and 60 nM for GSK-3βWT(1 h preincubation)and GSK-3βC199A(1 h preincubation), respectively. price>
R-R-2867 V-0219 hydrochloride CAS No.2922283-73-4 V-0219 hydrochloride (Compound 9)/CAS No.2922283-73-4 is an orally active, positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R). V-0219 hydrochloride can be used for obesity-associated diabetes research. price>
R-C-1168 Elesclomol (STA-4783) CAS: 488832-69-5 Elesclomol(STA-4783)is an oxidative stress inducer that induces cancer cell apoptosis.Elesclomol is a reactive oxygen species(ROS)inducer.Elesclomol shows antitumor activity against a broad range of cancer cell types.Elesclomol is also a highly lipophilic Cu2+-binding molecule.Elesclomol can be used for Menkes and associated disorders of hereditary copper deficiency research. price>
R-R-2868 Apraglutide TFA Apraglutide TFA (FE 203799 TFA), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum. price>
R-C-1169 GW 627368 CAS: 439288-66-1 GW627368(GW627368X)is a novel,potent and selective competitive antagonist of prostanoid EP4 receptor with additional human TP receptor affinity, with pKi values of 7.0 and 6.8 for human prostanoid EP4 and TP receptors respectively. price>
R-R-2869 (S)-V-0219 hydrochloride (S)-V-0219 hydrochloride is an enantiomer of V-0219 (HY-143312). V-0219 is an orally active and positive allosteric modulator (PAM) of the GLP Receptor-1 (GLP-1R). (S)-V-0219 hydrochloride activates calcium fluxes in HEK cells stably expressing hGLP-1R. (S)-V-0219 hydrochloride is orally active and ameliorates high glucose levels in mice and inhibits feeding behavior in fasted mice. price>
R-C-1170 cevipabulin CAS:849550-05-6 Cevipabulin(TTI-237),an antimicrotubule agent,is a small synthetic molecule of triazolopyrimidine derivative with potential antitumor activity.With a novel mechanism of action distinct from the action of other vinca alkaloid compounds, TTI-237 specifically binds to tubulin at the vinca site,and promotes the polymerization of tubulin into microtubules. price>
R-R-2870 GLP-1 receptor agonist 11 CAS No.2784590-83-4 GLP-1 receptor agonist 11 (compound 3)/CAS No.2784590-83-4 is an agonist of GLP Receptor. GLP-1 receptor agonist 11 can be used in the study of diseases such as diabetes and non-alc. fatty liver disease. price>
R-C-1171 LY2874455 CAS:1254473-64-7 LY2874455 is a pan-FGFR inhibitor with IC50 of 2.8 nM,2.6 nM,6.4 nM,and 6 nM for FGFR1,FGFR2,FGFR3,and FGFR4,respectively,and also inhibits VEGFR2 activity with IC50 of 7 nM. price>
R-R-2871 (R)-V-0219 hydrochloride (R)-V-0219 hydrochloride is an enantiomer of V-0219 (HY-143312). V-0219 is an orally active and positive allosteric modulator (PAM) of the GLP Receptor-1 (GLP-1R). (R)-V-0219 hydrochloride activates calcium fluxes in HEK cells stably expressing hGLP-1R. price>
R-C-1172 BLU-9931 CAS:1538604-68-0 BLU9931 is a potent,highly selective,and irreversible fibroblast growth factor receptor 4(FGFR4)inhibitor with an IC50 of 3 nM and a Kd of 6 nM.BLU9931 has significant antitumor activity. price>