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Catalog	name	Description	price
R-R-2872	GLP-1 receptor agonist 10	GLP-1 receptor agonist 10 (compound 42) is an agonist of GLP Receptor. GLP-1 receptor agonist 10 inhibits food intake and reduces glucose excursion in mice. GLP-1 receptor agonist 10 can be used in the study of type 2 diabetes (T2DM) and obesity.	price>
R-C-1173	TP-0903 CAS：1341200-45-0	TP-0903 is a potent and selective AXL Inhibitor with IC50 of 27 nM.TP-0903 is highly effective in inducing apoptosis.	price>
R-R-2873	HAEGT CAS No.852155-81-8	HAEGT/CAS No.852155-81-8 is the first N-terminal 1-5 residues of glucagon like peptide-1 (GLP-1) peptide, and the sequence is His-Ala-Glu-Gly-Thr. HAEGT acts as a competitive substrate for probing prime substrate binding sites of human dipeptidyl peptidase-IV (DPP-IV) 1, in which the N-terminal His-Ala is catalyzed cleavage by DPP-IV. HAEGT can be used in the research of diabetes, obesity.	price>
R-C-1174	Luminespib(NVP-AUY922) CAS：747412-49-3	Luminespib(AUY-922,NVP-AUY922,VER-52296)is a highly potent HSP90 inhibitor for HSP90α/β with IC50 of 13 nM /21 nM in cell-free assays,weaker potency against the HSP90 family members GRP94 and TRAP-1,exhibits the tightest binding of any small-molecule HSP90 ligand.Luminespib(AUY-922,NVP-AUY922)effectively downregulates and destabilizes the IGF-1Rβ protein and results in growth inhibition,autophagy and apoptosis.	price>
R-R-2874	3-Deoxyglucosone CAS No.4084-27-9	3-Deoxyglucosone (3-Deoxy-D-glucosone)/CAS No.4084-27-9 is a reactive intermediate of the Maillard reaction and the polyol pathway. 3-Deoxyglucosone rapidly reacts with protein amino groups to form advanced glycation end products (AGEs), such as imidazolone, it is the most specific AGE for 3-DG. 3-Deoxyglucosone synergizes with low glucose to potentiate GLP-1 secretion and is considered as a biomarker for diabetes.	price>
R-C-1175	SB590885 CAS：405554-55-4	SB-590885 is a potent B-Raf inhibitor with Ki of 0.16 nM,and has 11-fold greater selectivity for B-Raf over c-Raf,without inhibition to other human kinases.	price>
R-R-2875	Albiglutide fragment TFA	Albiglutide fragment (GLP-1 (7-36) analog) TFA is an active fragment of Albiglutide (7-36) and a glucagon-like peptide-1 (GLP-1) analog (a long-acting GLP-1 receptor agonist). Albiglutide is produced by the fusion of DPP-4 resistant GLP-1 dimer with the human albumin gene. Moreover, Albiglutide fragment TFA significantly reduces glycosylated hemoglobin (A1C) and is used in type 2 diabetes (T2D) studies.	price>
R-C-1176	MK1775 CAS：955365-80-7	Adavosertib is a small molecule inhibitor of the tyrosine kinase WEE1 with potential antineoplastic sensitizing activity.Adavosertib selectively targets and inhibits WEE1,a tyrosine kinase that phosphorylates cyclin-dependent kinase 1(CDK1,CDC2)to inactivate the CDC2/cyclin B complex.Inhibition of WEE1 activity prevents the phosphorylation of CDC2 and impairs the G2 DNA damage checkpoint. This may lead to apoptosis upon treatment with DNA damaging chemotherapeutic agents.Unlike normal cells,most p53 deficient or mutated human cancers lack the G1 checkpoint as p53 is the key regulator of the G1 checkpoint and these cells rely on the G2 checkpoint for DNA repair to damaged cells.	price>
R-R-2876	HAEGTFTSDVSSYLE CAS No.926018-57-7	HAEGTFTSDVSSYLE/CAS No.926018-57-7 is a polypeptide from patent CN 102920658 B. GLP-I analog contains the sequence.	price>
R-C-1177	GS-7340(Tenofovir alafenamide ) CAS：379270-37-8	Tenofovir Alafenamide(GS-7340)is a prodrug of tenofovir,which is a reverse transcriptase inhibitor,used to treat HIV and Hepatitis B.	price>
R-R-2877	PA-8 CAS No.878437-15-1	PA-8/CAS No.878437-15-1 is a potent, selective and orally active PACAP type I (PAC1) receptor antagonist. PA-8 inhibits the phosphorylation of CREB induced by PACAP in PAC1-, but not VPAC1- or VPAC2-receptor. PA-8 also inhibits PACAP-induced cAMP elevation with an IC50 of 2 nM.	price>
R-C-1178	GSK503 CAS：1346572-63-1	GSK503 is a potent and specific inhibitor of EZH2 methyltransferase with Kiapp values of 3 to 27 nM.	price>
R-R-2878	PACAP (6-38), human, ovine, rat TFA	PACAP (6-38), human, ovine, rat TFA is a potent PACAP receptor antagonist with IC50s of 30, 600, and 40 nM for PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2, respectively.	price>
R-C-1179	CGI-1746 CAS：910232-84-7	CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation.	price>
R-R-2879	PAC1R antagonist 1 CAS No.2305204-24-2	PAC1R antagonist 1 (compound 3d)/CAS No.2305204-24-2 is a potent and orally active antagonist of PAC1 receptor. PAC1R antagonist 1 can inhibit pituitary adenylate cyclase-activating polypeptide (PACAP)- and nerve injury-induced allodynia.	price>
R-C-1180	Endoxifen CAS：112093-28-4	Endoxifen is a secondary metabolite of tamoxifen.It is a primary metabolite responsible for the effectiveness of tamoxifen in ER-positive breast cancer.	price>
R-R-2880	PACAP (1-27), human, ovine, rat TFA	PACAP (1-27), human, ovine, rat TFA (PACAP 1-27 TFA) is the N-terminal fragment of PACAP-38, and is a potent PACAP receptor antagonist with IC50s of 3 nM, 2 nM and 5 nM for rat PAC1, rat VPAC1 and human VPAC2, respectively.	price>
R-C-1181	D-Luciferin CAS ：2591-17-5	D-Luciferin is a popular bioluminescent substrate of luciferase in the presence of ATP,used in luciferase-based bioluminescence imaging and cell-based high-throughput screening applications.	price>
R-R-2881	PACAP (1-38), amide, Biotin-labeled	PACAP (1-38), amide, Biotin-labeled is a biological active peptide. (Biotin-labeled HY-P0221)	price>
R-C-1182	NS6180	NS6180 is a novel potent and selective KCa3.1 channel inhibitor(IC50=9nM) prevents T-cell activation and inflammation.	price>

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