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Catalog	name	Description	price
R-C-1472	CP544326 (Taprenepag) CAS:752187-80-7	Taprenepag(CP-544326)is a potent and selective prostaglandin EP(2)agonist with IC50s of 10 and 15 nM for human and rat EP2,respectively.Taprenepag shows selectivity for EP2 over other EP receptors(IC50s>3200 nM for EP1,EP3,and EP4)and a panel of 37G protein-coupled receptors.	price>
R-R-3172	Cyproheptadine CAS No.129-03-3	Cyproheptadine/CAS No.129-03-3 is a potent and orally active 5-HT2A receptor antagonist, with antidepressant and antiserotonergic effects. Cyproheptadine has antiplatelet and thromboprotective activities. Cyproheptadine can be used for the research of thromboembolic disorders.	price>
R-C-1473	ZM241385 CAS:139180-30-6	ZM-241385 is a potent and highly selective Adenosine A2A-R antagonist,with a pA2 of 9.02 for Adenosine A2A-R in cardiac vasculature and selectivities of 1000,91 and 500,000 over Adenosine A1-R,Adenosine A2B-R and Adenosine A3-R sites, respectively.	price>
R-R-3173	JNJ-18038683 CAS No.851376-05-1	JNJ-18038683 is a 5-Hydroxytryptamine Type 7 (5-HT7) receptor antagonist, with pKis of 8.19, 8.20 for rat and human 5-HT7 in HEK293 cells, respectively.	price>
R-C-1474	BX-912 CAS:702674-56-4	BX912 is a potent and specific PDK1 inhibitor with IC50 of 12 nM,9-and 105- fold greater selectivity for PDK1 than PKA and PKC in cell-free assays, respectively.In comparison to GSK3β,selectivity for PDK1 is 600-fold.	price>
R-R-3174	Ocaperidone CAS No.129029-23-8	Ocaperidone/CAS No.129029-23-8 is an effective antipsychotic agent, acting as a potent 5-HT2 and dopamine D2 antagonist, and a 5-HT1A agonist, with Kis of 0.14 nM, 0.46 nM, 0.75 nM, 1.6 nM and 5.4 nM for 5-HT2, a1-adrenergic receptor, dopamine D2, histamine H1 and a2-adrenergic receptor, respectively, and a pEC50 and pKi of 7.60 and 8.08 for h5-HT1A.	price>
R-C-1475	PGA-PEG-malemide	Polyglutamic acid（γ-PGA,also known as natto gum and polyglutamic acid,is a kind of water-soluble,biodegradable,non-toxic biopolymer produced by microbial fermentation.Polyethylene glycol(PEG)is a kind of high molecular polymer,the chemical formula is ho(CH2CH2O)NH,which has no irritation,slightly bitter taste,good water solubility and good compatibility with many organic components.	price>
R-R-3175	Phenylbiguanide CAS No.102-02-3	Phenylbiguanide/CAS No.102-02-3 is a 5-HT3 receptor selective agonist with an EC50 of 3.0±0.1 μM.	price>
R-C-1476	MK-3697 CAS:1224846-01-8	MK-3697 is a highly potent,orally bioavailable selective orexin 2 receptor antagonists.MK-3697 is also the third insomnia drug,currently being developed by Merck.MK-3697 has Ki=0.95nM.Orexin receptor antagonists have demonstrated clinical utility for the treatment of insomnia.In vivo tests results on MK-3697 demonstrated improved stability and TDI profiles as well as excellent sleep efficacy across species.	price>
R-R-3176	Zacopride hydrochloride CAS No.101303-98-4	Zacopride hydrochloride/CAS No.101303-98-4 is a highly potent 5-HT3 receptor antagonist with Kis of 0.38 and 373 nM for 5-HT3 and 5-HT4 receptor, respectively. Zacopride hydrochloride is also a moderate IK1 channel agonist. Zacopride hydrochloride exerts significant antiarrhythmic and cardiac protective effects.	price>
R-C-1477	bay1217389 CAS:1554458-53-5	BAY 1217389 is an orally bioavailable,selective inhibitor of the serine/threonine kinase monopolar spindle 1(Mps1)with IC50 values below 10 nmol/L while showing an excellent selectivity profile.	price>
R-R-3177	Flibanserin CAS No.167933-07-5	Flibanserin (BIMT-17; BIMT-17BS)/CAS No.167933-07-5 is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin binds to dopamine D4 receptors with an Ki value of 4-24 nM. Flibanserin shows anti-depression and anti-anxiety effect, can be used to hypoactive sexual desire disorder (HSDD) research-.	price>
R-C-1478	PF-2545920 CAS:1292799-56-4	Mardepodect(PF-2545920)is a potent,orally active and selective PDE10A inhibitor with an IC50 of 0.37 nM,with>1000-fold selectivity over other PDEs. Mardepodect can cross the blood-brain barrier.	price>
R-R-3178	Iloperidone CAS No.133454-47-4	Iloperidone (HP 873)/CAS No.133454-47-4 is a D2/5-HT2 receptor antagonist. Iloperidone is an atypical antipsychotic for the schizophrenia symptoms.	price>
R-C-1479	SEA0400 CAS:223104-29-8	SEA0400 is a selective and potent inhibitor of the Na+-Ca2+ exchanger(NCX)that inhibits Na+-dependent Ca2+ uptake in cultured neurons, astrocytes,and microglia with IC50 of 33 nM,5.0nM and 8.3 nM,respectively.SEA0400 prevents sodium nitroprusside(SNP)from increasing ERK and p38 MAPK phosphorylation and production of reactive oxygen species(ROS)in an extracellular Ca(2+)-dependent manner.	price>
R-R-3179	Naratriptan hydrochloride CAS No.143388-64-1	Naratriptan hydrochloride/CAS No.143388-64-1 is a selective 5-HT1 receptor subtype agonist and is a triptan drug that is used for the treatment of migraine headaches.	price>
R-C-1480	MBX-2982 CAS:1037792-44-1	MBX-2982 is a potential first-in-class treatment for type 2 diabetes that targets G protein-coupled receptor 119(GPR119),a receptor that interacts with bioactive lipids known to stimulate glucose-dependent insulin secretion.	price>
R-R-3180	Quipazine CAS No.4774-24-7	Quipazine/CAS No.4774-24-7 is a 5-HT agonist with a Ki value of 1.4 nM for displaces [3H]GR65630 from 5-HT3R in rat. Quipazine shows antiviral activity against SARS-CoV-2 with an EC50 of 31.64 μM. Quipazine behaves as a 5-HT3R agonist in peripheral models. Quipazine can be used for neurological disease research.	price>
R-C-1481	GSK2330672 CAS:1345982-69-5	Linerixibat(GSK2330672)is a highly potent,nonabsorbable and orally active apical sodium-dependent bile acid transporter(ASBT)inhibitor with an IC50 of 42 nM human ASBT.Linerixibat can be used as lipid-lowering agent. Linerixibat has the potential for type 2 diabetes and Primary Biliary Cholangitis treatment.	price>
R-R-3181	NAN-190 hydrobromide CAS No.115338-32-4	NAN-190 hydrobromide/CAS No.115338-32-4 is a serotonin receptor 5-HT antagonist. NAN-190 is a selective antagonist of 5-HT1A.	price>

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