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Catalog	name	Description	price
R-R-3282	(S)-Mirtazapine CAS No.61337-87-9	(S)-Mirtazapine ((S)-Org3770)/CAS No.61337-87-9 is a S(+)-enantiomer of Mirtazapine with pronociceptive properties in an animal model of acute thermal nociception. (S)-Mirtazapine is a stereoselective 5-HT2 receptor antagonist. (S)-Mirtazapine is metabolized by CYP2D6 and CYP1A2.	price>
R-C-1583	Alvespimycin	Alvespimycin is a heat shock protein 90(Hsp90)inhibitor and promising therapeutic agent for cancer.	price>
R-R-3283	Repinotan hydrochloride CAS No.144980-77-8	Repinotan hydrochloride (BAY x 3702)/CAS No.144980-77-8 is a potent, selective, brain-penetrant and orally active 5-HT1A receptor agonist, with Ki values of 0.19 nM (calf hippocampus), 0.25 nM (rat and human cortex), and 0.59 nM (rat hippocampus Repinotan hydrochloride has a weak affinity for other related receptors. Repinotan hydrochloride has pronounced neuroprotective effects.	price>
R-C-1584	GRT6005(Cebranopadol) CAS:863513-91-1	Cebranopadol(GRT-6005)is a Opioid Receptor Agonist with agonistic activity at nociceptin/orphanin FQ and opioid receptors.Cebranopadol displays analgesic, antiallodynic and antihyperalgesic properties in several rat models of acute nociceptive,inflammatory,cancer and neuropathic pain.In contrast to classical opioids,it has a higher analgesic potency in models of neuropathic pain than in acute nociceptive pain.Even at higher analgesic doses,cebranopadol does not induce motor coordination deficits or respiratory depression in rats.	price>
R-R-3284	Clothiapine CAS No.2058-52-8	Clothiapine/CAS No.2058-52-8, an atypical antipsychotic agent, shares with clozapine its strong antiserotonergic properties.	price>
R-C-1585	VR23 CAS : 1624602-30-7	VR23 is a small molecule that potently inhibited the activities of trypsin-like proteasomes(IC50=1nM),chymotrypsin-like proteasomes(IC50=50-100nM),and caspase-like proteasomes(IC50=3uM).	price>
R-R-3285	Renzapride CAS No.112727-80-7	Renzapride (BRL 24924)/CAS No.112727-80-7, a substituted benzamide, is a full 5-HT4 receptor agonist with a Ki value of 115 nM. Renzapride (BRL 24924) is also a 5HT2b and 5HT3 receptor antagonist. Renzapride could be used for constipation predominant irritable bowel syndrome (C-IBS) study.	price>
R-C-1586	TGX-221 CAS:663619-89-4	TGX-221 is a potent,selective,and cell membrane permeable inhibitor of the PI3K p110β catalytic subunit,used for cancer treatment.	price>
R-R-3286	Dolasetron Mesylate hydrate CAS No.878143-33-0	Dolasetron Mesylate hydrate (MDL-73147EF hydrate)/CAS No.878143-33-0 is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.	price>
R-C-1587	T-5224 CAS:530141-72-1	T-5224 is a selective inhibitor of transcription factor c-Fos/activator protein (AP)-1 with anti-inflammatory effects.T-5224 specifically inhibits the DNA binding activity of c-Fos/c-Jun and the IL-1β-induced up-regulation of Mmp-3,Mmp-13 and Adamts-5 transcription.	price>
R-R-3287	Ampreloxetine TFA	Ampreloxetine (TD-9855) TFA is a potent and orally active norepinephrine (NE) and serotonin 5-HT inhibitor. Ampreloxetine TFA has the potential for the research of neurogenic orthostatic hypotension.	price>
R-C-1588	Scriptaid CAS:287383-59-9	Scriptaid is a potent histone deacetylase(HDAC)inhibitor,used in cancer research.Scriptaid is also a sensitizer to antivirals and has potential for epstein-barr virus(EBV)-associated lymphomas treatment.	price>
R-R-3288	BRL-15572 dihydrochloride CAS No.193611-72-2	BRL-15572 dihydrochloride/CAS No.193611-72-2 is a selective antagonist of h5-HT1D, displays high affinity for h5-HT1D receptors. BRL-15572 dihydrochloride could be useful pharmacological agents to characterise 5-HT1D receptor mediated responses.	price>
R-C-1589	SB 366791 CAS:472981-92-3	SB-366791 is a potent,competitive and selective vanilloid receptor(VR1/TRPV1) antagonist with IC50 of 5.7±1.2 nM target:VR1/TRPV1 IC 50:5.7±1.2 nM[1] SB-366791 produced a concentration-dependent inhibition of the response to capsaicin with an apparent pKb of 7.74±0.08.	price>
R-R-3289	Quetiapine-d4 fumarate CAS No.1287376-15-1	Quetiapine-d4 (fumarate)/CAS No.1287376-15-1 is the deuterium labeled Quetiapine fumarate. Quetiapine fumarate is a 5-HT receptors agonist and a dopamine receptor antagonist. Antidepressant and anxiolytic effects.	price>
R-C-1590	Apabetalone (RVX-208) CAS:1044870-39-4	Apabetalone(RVX-208)is an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain.The IC50s are 87 μM and 0.51 μM for BD1 and BD2,respectively.	price>
R-R-3290	Buspirone CAS No.36505-84-7	Buspirone/CAS No.36505-84-7 is an orally active 5-HT1A receptor agonist, and a dopamine D2 autoreceptorsant antagonist. Buspirone is an anxiolytic agent, and can be used for the generalized anxiety disorder research.	price>
R-C-1591	ON123300 CAS:1357470-29-1	ON123300,a strong and brain-penetrant multi-kinase inhibitor, inhibits CDK4(IC50=3.9nM),Ark5(IC50=5nM),PDGFRβ(IC50=26 nM),FGFR1(IC50=26 nM),RET(IC50=9.2nM),and FYN(IC50=11nM).Single agent ON123300 causes a dose-dependent suppression of phosphorylation of Akt as well as activation of Erk in brain tumors.ON123300 inhibits CDK6 with an IC50 of 9.82 nM.	price>
R-R-3291	Rodatristat CAS No.1673568-73-4	Rodatristat (KAR5417)/CAS No.1673568-73-4 is a potent tryptophan hydroxylase 1 (TPH1) and TPH2 inhibitor with IC50s value of 33 nM and 7 nM, respectively, and shows robust reduction of intestinal serotonin (5-HT) levels in mice.	price>
R-C-1592	Napabucasin (BBI608) CAS:83280-65-3	Napabucasin is a STAT3 inhibitor which blocks stem cell activity in cancer cells.	price>

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