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Catalog	name	Description	price
R-C-1613	Pluripotin (SC1) CAS：839707-37-8	Pluripotin(SC1)is a dual inhibitor of extracellular signal-regulated kinase 1(ERK1,MAPK3)and RasGAP.Maintains embryonic stem cell(ESC)self-renewal.Pluripotin also inhibits RSK1,RSK2,RSK3 and RSK4 with IC50 of 0.5 µM,2.5 µM,3.3µM and 10.0µM,respectively.	price>
R-R-3313	Amperozide CAS No.75558-90-6	Amperozide/CAS No.75558-90-6 is an atypical antipsychotic that acts as an antagonist of the 5-HT2 receptor with a Ki value of 26 nM. Amperozide has a low affinity for D2 receptors.	price>
R-C-1614	BMS309403 CAS：300657-03-8	BMS-309403 is a potent,orally active and selective adipocyte fatty acid binding protein(also known as FABP4,aP2)inhibitor with Kis of <2,250,and 350 nM for FABP4,FABP3,and FABP5,respectively.BMS-309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids.BMS-309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells.	price>
R-R-3314	BMY 14802 CAS No.105565-56-8	BMY 14802/CAS No.105565-56-8 is a sigma-1 receptor (σ1R) antagonist, as well as an agonist at serotonin (5-HT) 1A and adrenergic alpha-1 receptors.	price>
R-C-1615	SIS3 HCL CAS：521984-48-5	SIS3 is a novel specific inhibitor of Smad3.It has effect on transforming growth factor-beta1-induced extracellular matrix expression.	price>
R-R-3315	LY 165163 CAS No.1814-64-8	LY 165163/CAS No.1814-64-8 is a potent 5-HT presynaptic receptor agonist. LY 165163 significantly decreases 5-HTP accumulation and increases DOPA accumulation in the cortex and striatum.	price>
R-C-1616	A804598 CAS:1125758-85-1	A-804598 is a CNS penetrant,competitive and selective P2X7 receptor antagonist with IC50s of 9 nM,10nM and 11 nM for mouse,rat and human P2X7 receptors, respectively.	price>
R-R-3316	Iferanserin CAS No.58754-46-4	Iferanserin (S-MPEC)/CAS No.58754-46-4 is a selective 5-HT receptor (serotonin receptor) antagonist with an affinity for 5-HT2A receptor. Iferanserin has the potential for internal hemorrhoid disease treatment.	price>
R-C-1617	GW4869 CAS:6823-69-4	GW4869(GW69A,GW554869A)is a neutral,noncompetitive inhibitor of sphingomyelinase (SMase)with an IC50 of 1μM.It is selective for N-SMase,and does not inhibit acid SMase at up to at least 15μM.	price>
R-R-3317	Olanzapine-d3 CAS No.786686-79-1	Olanzapine-d3/CAS No.786686-79-1 is the deuterium labeled Olanzapine. Olanzapine is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptors (Ki=19 nM). Olanzapine is an atypical antipsychotic.	price>
R-C-1618	BAW2881 CAS： 861875-60-7	NVP-BAW2881(BAW2881)is a potent and selective VEGFR2 inhibitor with an IC50 of 4nM.	price>
R-R-3318	Keto Ziprasidone CAS No.884305-07-1	Keto Ziprasidone/CAS No.884305-07-1 is an impurity of Ziprasidone. Ziprasidone, an antipsychotic agent, is a combined 5-HT (serotonin) and dopamine receptor antagonist.	price>
R-C-1619	BFH772 CAS ：890128-81-1	BFH772,a structure analogue of BAW2881,is a potent and selective VEGF inhibitor.BFH772 is highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM.BFH772 inhibits the ligand induced autophosphorylation of RET, PDGFR,and KIT kinases,with IC50 values ranging between 30 and 160 nM.	price>
R-R-3319	(R)-Mirtazapine CAS No.61364-37-2	(R)-Mirtazapine ((R)-Org3770)/CAS No.61364-37-2 is a R(−)-enantiomer of Mirtazapine with antinociceptive properties in an animal model of acute thermal nociception. (R)-Mirtazapine is a 5-HT3 receptor antagonist. (R)-Mirtazapine is mainly metabolized by CYP3A4.	price>
R-C-1620	HMN-214 CAS No. 173529-46-9	HMN-214 inhibits polo-like and cyclin-dependent kinase activity,has potent antimicrotubular effects and results in profound apoptosis and antitumor activity in a broad spectrum of human xenografts.	price>
R-R-3320	OPC-14523 hydrochloride CAS No.145969-31-9	OPC-14523 hydrochloride/CAS No.145969-31-9 is an orally active sigma and 5-HT1A receptor agonist, with high affinity for sigma receptors (σ1/2 IC50=47/56 nM), the 5-HT1A receptor (IC50=2.3 nM), and the 5-HT transporter (IC50=80 nM). OPC-14523 hydrochloride shows antidepressant-like activity.	price>
R-C-1621	HMN-176 CAS No. 173529-10-7	HMN-176 is an active metabolite of HMN-214,which has a potent antitumor activity in mouse xenograft models.HMN-176 effectively inhibits PLK-1 by interference with its normal subcellular spatial distribution at centrosomes and along the cytoskeletal structure.	price>
R-R-3321	Clozapine-d4 CAS No.204395-52-8	Clozapine-d4/CAS No.204395-52-8 is the deuterium labeled Clozapine. Clozapine is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors.	price>
R-C-1622	U93631 CAS:152273-12-6	U93631 is a GABAA receptor ligand of novel chemical structure with IC50 of 100 nM,and has been shown to induce a rapid,time-dependent decay of GABA-induced whole-cell Cl-currents in recombinant GABAA receptors.	price>
R-R-3322	F 13714 fumarate CAS No.208109-39-1	F13714 fumarate/CAS No.208109-39-1, a selective 5-HT1A receptor biased agonist, shows antidepressant-like properties after a single administration in the mouse model of chronic mild stress.	price>

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