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R-C-1624 HUHS015 CAS:1453097-13-6 HUHS015 is a potent PCA-1/ALKBH3 inhibitor both in vitro and in vivo.The bioavailability(BA)of HUHS015 was 7.2% in rats after oral administration. Continuously administering HUHS015 significantly suppressed the growth of DU145 cells,which are human hormone-independent prostate cancer cells,in a mouse xenograft model without untoward effects. price>
R-R-3323 CJ033466 CAS No.519148-48-2 CJ033466/CAS No.519148-48-2 is a novel and selective 5-HT4 receptor partial agonist with an EC50 of 9 nM and has gastroprokinetic effect. price>
R-C-1623 ML141 CAS:71203-35-5 ML141(CID-2950007)is demonstrated to be a potent,selective and reversible non-competitive inhibitor of Cdc42 GTPase suitable for in vitro assays, with IC50 of 200 nM and selectivity against other members of the Rho family of GTPases(Rac1,Rab2,Rab7).ML141 is associated with an increase in p38 activation and may induce p38-dependent apoptosis/senescence.ML141 also protects neuroblastoma cells from metformin-induced apoptosis. price>
R-R-3324 (Rac)-WAY-161503 CAS No.75704-24-4 (Rac)-WAY-161503/CAS No.75704-24-4 is a potent, selective, highly affinity 5-HT2C receptor agonist with a Ki of 4 nM and an EC50 of 12 nM. (Rac)-WAY-161503 displays higher affinity for 5-HT2C than 5-HT2A and 5-HT2B receptors. (Rac)-WAY-161503 has anti-obesity and antidepressant effects. price>
R-C-1625 Sotagliflozin (LX4211) CAS:1018899-04-1 Sotagliflozin(LX4211)is an orally active and a dual SGLT1/SGLT2 inhibitor, which improves glycemic control in patients with type 2 diabetes in a randomized,placebo-controlled trial.LX4211 increases serum glucagon-like peptide 1 and peptide YY levels by reducing sodium/glucose cotransporter 1(SGLT1)-mediated absorption of intestinal glucose. price>
R-R-3325 RU 24969 succinate CAS No.107008-28-6 RU 24969 succinate/CAS No.107008-28-6 is a 5-HT receptor agonist with Ki values of 0.38 and 2.5 nM for 5-HT1B and 5-HT1A, respectively. RU 24969 decreases fluid consumption and increases forward locomotion. RU 24969 succinate can be used for the research of neurological disease. price>
R-R-3326 Almotriptan CAS No.154323-57-6 Almotriptan/CAS No.154323-57-6 is a selective agonist of 5-HT 1B/1D Receptor. Almotriptan can used in study of migraine attacks. price>
R-C-1626 GSK9311 CAS:1923851-49-3 GSK9311,a less active analogue of GSK6853, can be used as a negative control. GSK9311 inhibits BRPF bromodomain with pIC50 values of 6.0 and 4.3 for BRPF1 and BRPF2,respectively. price>
R-C-1627 HG-10-102-01 CAS:1351758-81-0 HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2(LRRK2;IC50=20.3 nM).HG-10-102-01 is a potent and selective inhibitor of wild-type LRRK2 and the G2019S mutant.HG-10-102-01 substantially inhibits Ser910 and Ser935 phosphorylation of both wild-type LRRK2 and G2019S mutant at a concentration of 0.1-0.3 µM in cells and is the first compound reported to be capable of inhibiting Ser910 and Ser935 phosphorylation in mouse brain following intraperitoneal delivery of doses as low as 50 mg/kg. price>
R-R-3327 GR-46611 CAS No.185259-85-2 GR-46611/CAS No.185259-85-2 is a 5-HT1D receptor agonist. GR-46611 can be used in the research of bladder hyperactivity, leukemia. price>
R-C-1628 GSK2816126 CAS:1346574-57-9 GSK126(GSK2816126A,GSK2816126)is a potent, highly selective EZH2 methyltransferase inhibitor with IC50 of 9.9 nM,>1000-fold selective for EZH2 over 20 other human methyltransferases. price>
R-M-G08 Resorcinol organic aerogel Resorcinol organic aerogel is a highly porous and lightweight material formed through the gelation and subsequent drying of resorcinol and formaldehyde. This organic aerogel exhibits exceptional properties such as high surface area, low density, and thermal insulation. It finds applications in areas such as environmental remediation, thermal insulation, energy storage, and as a substrate for catalysts or sensors. Due to its unique structure and properties, it is also of interest for research in advanced materials and nanotechnology. price>
R-C-1629 CUDC-908 CAS:1235449-52-1 BEBT-908(CUDC-908,PI3Kαinhibitor 1,MDK9521,PI3Kα-IN-243)is a potent selective inhibitor of PI3Kα with IC50<0.1μM.BEBT-908 also inhibits HDAC with IC50≤1μM. price>
R-M-G09 TiO-SiO composite aerogel TiO-SiO composite aerogel/Titanium Dioxide-Silica Composite Aerogel is a material that combines titanium dioxide (TiO2) and silica (SiO2) into a porous, lightweight structure. This composite aerogel possesses properties such as high surface area, low density, and potential photocatalytic activity due to the presence of titanium dioxide. It can be utilized in applications such as environmental remediation, photocatalysis, and as an insulating material. Additionally, its unique structure and properties make it suitable for use in various advanced technological and scientific applications. price>
R-C-1630 Danirixin (GSK1325756) CAS:954126-98-8 Danirixin(GSK1325756)is a small molecule,non-peptide, high affinity(IC50 for CXCL8(IL-8)binding = 12.5nM),selective,and reversible CXCR2 antagonist. price>
R-M-G10 FeO-SiO Aerogel FeO-SiO Aerogel/Iron oxide-silica aerogel is a composite material formed by combining iron oxide (FeO) and silica (SiO2) into a highly porous, lightweight network. This aerogel exhibits properties such as high surface area, low density, and potential magnetic characteristics due to the presence of iron oxide. It can be applied in various fields such as catalysis, adsorption, and magnetic separation due to its unique properties. Additionally, its porous structure makes it suitable for applications like insulation and environmental remediation. price>
R-C-1631 GSK2879552 CAS:1401966-69-5 GSK2879552 an orally active, selective and irreversible inhibitor of lysine specific demethylase 1(LSD1/ KDM1A),with potential antineoplastic activity. price>
R-M-G11 NiO/SiO2 Aerogel Nickel Oxide-Silica aerogel;NiO/SiO2 Aerogel is a composite material consisting of nickel oxide (NiO) and silica (SiO2) structured as a highly porous, lightweight substance. This aerogel demonstrates characteristics such as high surface area, low density, and potential catalytic properties due to the presence of nickel oxide. It can be utilized in various applications, including catalysis, gas sensing, and energy storage, owing to its unique properties. Moreover, its porous nature makes it suitable for applications in insulation and environmental remediation. price>
R-C-1632 Pluronic F-127-PEI Pluronic F-127 is a trade name for synthetic polymer poloxamer-based polymeric compound.It exhibits a polymeric architecture consisting of two hydrophilic blocks between a hydrophobic block making it an effective surfactant.119 There are 11 types of Pluronic polymers which differ by molar mass,percentage of composites,functionality,and temperature of cross-linking which can vary from 10°C to 40°C.61Pluronic copolymer structures erode quickly and cannot hold structural integrity for longer than a few hours; however,Pluronic,in combination with other hydrogels such as PEG,is useful for drug delivery and controlled release applications. price>
R-M-G12 Manganese/Cerium Oxide Aerogel Manganese/Cerium Oxide Aerogel;CeO2 aerogel Mn/CeO2;Cerium oxide aerogel Mn/CeO2 is a composite material formed by combining manganese oxide (MnOx) with cerium oxide (CeO2) in an aerogel structure. This aerogel possesses a high surface area, low density, and has the potential to exhibit catalytic activity due to the presence of manganese and cerium oxides. It can find applications in catalysis, gas sensing, and energy storage, and its unique properties make it suitable for various advanced technological and scientific applications. price>