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Catalog	name	Description	price
R-C-1643	FYX 051(Topiroxostat) CAS:577778-58-6	Topiroxostat(FYX-051)is a potent and orally active xanthine oxidoreductase (XOR)inhibitor with an IC50 value of 5.3 nM and a Ki value of 5.7nM. Topiroxostat exhibits weak CYP3A4-inhibitory activity(18.6%).Topiroxostat has the potential for hyperuricemia treatment.	price>
R-M-G23	Polyimide Aerogel with SiO2 Nanospheres	Polyimide Aerogel with SiO2 Nanospheres/Polyimide Aerogel with Silica Nanospheres is a composite material that integrates SiO2 nanospheres into a polyimide aerogel structure. This material combines the advantageous properties of polyimide, known for its high-temperature stability and mechanical strength, with the unique characteristics of SiO2 nanospheres, which provide a high surface area and porous structure. The resulting composite material exhibits potential for applications in insulation, aerospace, and as a lightweight structural material. Additionally, the incorporation of SiO2 nanospheres enhances thermal and mechanical properties while maintaining a low density, making it suitable for various advanced technological and scientific applications, particularly in high-temperature environments and aerospace engineering.	price>
R-C-1644	TOFA (5-(Tetradecyloxy)-2-furoic acid） CAS:54857-86-2	TOFA(5-(Tetradecyloxy)-2-furoic acid,Tyrphostin 46,Tyrphostin A46,Tyrphostin B40)is an allosteric inhibitor of acetyl-CoA carboxylase-α(ACCA).Inside the cell,TOFA is converted to TOFyl-CoA(5-tetradecyloxy-2-furoyl-CoA),exerting an allosteric inhibition on ACCA.TOFA blocks fatty acid synthesis and induces cell death in a dose-dependent manner.	price>
R-M-G24	(Y2O3) yttrium oxide doped alumina (Al2O3) bulk aerogel	(Y2O3) yttrium oxide doped alumina (Al2O3) bulk aerogel; yttrium oxide doped alumina bulk aerogel;Y2O3 doped Al2O3 bulk aerogel, the doping content is controlled in the range of 2.5wt% ~ 30wt% Y2O3. The results show that the doping of yttrium oxide can make the alumina aerogel in Maintain a high specific surface area and improve its thermal stability at high temperatures. After heat treatment at 1000°C, the 5.0wt% Y2O3-Al2O3 aerogel is still in an amorphous form, without phase transition, and the specific surface area is still 380~400 m2/ g, much higher than pure Al2O3 aerogel (174 m2/g).	price>
R-C-1645	ITSA-1 (ITSA1) CAS:200626-61-5	ITSA-1 is an activator of histone deacetylase(HDAC),and counteract trichostatin A(TSA)-induced cell cycle arrest,histone acetylation,and transcriptional activation.	price>
R-R-3345	Ro60-0175 fumarate CAS No.169675-09-6	Ro60-0175 fumarate/CAS No.169675-09-6 is a potent and selective agonist of 5-HT2C receptor.	price>
R-C-1646	Lys05 CAS:1391426-22-4	Lys05 is a potent lysosomal autophagy inhibitor.Lys05 is a previously undescribed dimeric chloroquine which more potently accumulates in the lysosome and blocks autophagy compared with HCQ.	price>
R-R-3346	(S)-Amisulpride CAS No.71675-92-8	(S)-Amisulpride (Esamisulpride)/CAS No.71675-92-8 is a potent dopamine D2/D3 receptor antagonist. (S)-Amisulpride is an antagonist at the 5-HT7 receptor with a KI of 900 nM. (S)-Amisulpride has antipsychotic and antidepressant effects.	price>
R-C-1647	Importazole CAS:662163-81-7	Importazole is a small molecule inhibitor of the transport receptor importin-β (Karyopherin beta)specifically blocking importin-β-mediated nuclear import. Importazole induces apoptosis and inhibits tumor growth.	price>
R-R-3347	SB228357 CAS No.181629-93-6	SB228357/CAS No.181629-93-6 is a selective, potent and orall active 5-HT2C/2B receptor antagonist with pKi values of 6.9, 8.0 and 9.0 for 5-HT2A, 5-HT2B and 5-HT2C, respectively. SB228357 has antidepressant/anxiolytic effects.	price>
R-C-1648	Miransertib (ARQ-092) CAS:1313881-70-7	Miransertib(ARQ-092)is a potent,selective and orally bioavailable allosteric inhibitor of Akt with IC50s of 2.7nM,14 nM and 8.1nM for Akt1,Akt2,Akt3.	price>
R-R-3348	SB-200646A CAS No.143797-62-0	SB-200646A/CAS No.143797-62-0 is the first selective 5-HT2B/2C over 5-HT2A receptor antagonist with pKi values of 7.5, 6.9 and 5.2 for 5-HT2B, 5-HT2C and 5-HT2A, respectively. SB-200646A is orally active and has electrophysiological and anxiolytic properties in vivo.	price>
R-R-3349	PU02 CAS No.313984-77-9	PU02/CAS No.313984-77-9, a derivative of 6-MP (HY-13677), is a negative allosteric modulator (NAM) of 5-HT3 receptor, with IC50 values of 0.36 and 0.73 μM in HEK293 cells transfected with human 5-HT3A and 5-HT3AB receptors respectively.	price>
R-C-1649	SKF96365.HCl CAS:130495-35-1	SKF-96365 hydrochloride is a potent TRP channel blocker and a store-operated Ca2+ entry(SOCE)inhibitor.SKF-96365 hydrochloride significantly inhibits hERG, hKCNQ1/hKCNE1,hKir2.1 and hKv4.3 current,and significantly prolongs the QTc interval in isolated guinea pig hearts.SKF-96365 hydrochloride exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal cancer cells.	price>
R-C-1650	AR-M1000390 HCl CAS:209808-47-9	AR-M1000390(ARM-390)is a nonpeptidic δ receptor selective agonist.	price>
R-R-3350	Alniditan dihydrochloride CAS No.155428-00-5	Alniditan (Alnitidan) dihydrochloride/CAS No.155428-00-5 is a potent 5-HT1B and 5-HT1D receptors agonist, with IC50s of 1.7 nM and 1.3 nM for h5-HT1B and h5-HT1D receptors in HEK 293 cells, respectively. Alniditan dihydrochloride has migraine-preventive effects.	price>
R-C-1651	nicainoprol CAS：76252-06-7	Nicainoprol is a fast-sodium-channel blocking drug,which is a potent antiarrhythmic agent.	price>
R-R-3351	Tedatioxetine hydrobromide CAS No.960151-65-9	Tedatioxetine (Lu AA24530) hydrobromide/CAS No.960151-65-9 acts as a serotonin and norepinephrine (NE)-preferring triple reuptake inhibitor (TRI) and 5-HT2A, 5-HT2C, 5-HT3 and α1A-adrenergic receptor antagonist.	price>
R-C-1652	DAA1106 CAS：220551-92-8	DAA1106 is a potent and selective ligand for peripheral benzodiazepine receptor (PBR),as a potent and selective agonist at the peripheral benzodiazepine receptor.	price>
R-R-3352	Naluzotan CAS No.740873-06-7	Naluzotan/CAS No.740873-06-7 is a novel, potent, and selective amidosulfonamide 5-HT1A agonist with IC50 and Ki of appr 20 nM and 5.1 nM, used for the treatment of anxiety and depression; Also a weak hERG K+ channel blocker, with IC50 of 3800 nM.	price>

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