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Catalog | name | Description | price |
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R-C-1673 | Idelalisib (CAL-101, GS-1101) CAS:870281-82-6 | Idelalisib (CAL-101,GS-1101)is a selective p110δ inhibitor with IC50 of 2.5 nM in cell-free assays;shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ,and 400- to 4000-fold more selectivity to p110δ than C2β,hVPS34,DNA-PK and mTOR.Idelalisib also stimulates autophagy. | price> |
R-AC-0017 | AgBr/titanium silicate aerogel | AgBr/titanium silicate aerogels;Silver bromide/titanium silicate aerogel ;AgBr/Ti silicate aerogel;Silver bromide/Ti silicate aerogel are advanced nanocomposites known for their exceptional properties and diverse applications. These aerogels consist of silver bromide (AgBr) nanoparticles incorporated within a titanium silicate matrix, resulting in a unique composite material with a range of advantageous characteristics.The presence of AgBr in the titanium silicate aerogel imparts significant photocatalytic properties. These aerogels are capable of initiating photochemical reactions under light irradiation, making them valuable for applications such as environmental remediation, water purification, and air treatment.AgBr/titanium silicate aerogels represent a promising class of nanocomposite materials with unique properties that make them suitable for a wide range of applications, including environmental remediation, antibacterial surfaces, optical devices, and energy-related technologies. | price> |
R-C-1674 | ETC-1002 CAS:738606-46-7 | ETC-1002(Bempedoic acid,ESP-55016),also known as Bempedoic acid, is an orally available,once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies.ETC-1002 is an activator of hepatic AMP-activated protein kinase(AMPK).It has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29uM). | price> |
R-AC-0018 | Cerium neodymium doped titanium dioxide/carbon hybrid aerogels | Cerium and neodymium doped titanium dioxide/carbon hybrid aerogels; Ce and Nd doped TiO2/carbon hybrid aerogels;Cerium and neodymium doped TiO2/carbon hybrid aerogels;Ce and Nd doped titanium dioxide/carbon hybrid aerogels are advanced nanocomposite materials that exhibit exceptional properties and are utilized across various fields due to their unique structure and composition. These aerogels are composed of titanium dioxide (TiO2) doped with cerium (Ce) and neodymium (Nd), integrated with a carbon framework, resulting in a multifunctional material with a wide range of advantageous characteristics. cerium and neodymium doped titanium dioxide/carbon hybrid aerogels represent a highly versatile class of nanocomposite materials, offering a unique combination of properties suitable for applications in environmental remediation, energy storage, flexible electronics, and beyond. | price> |
R-C-1675 | AR7 CAS:80306-38-3 | AR7 is an atypical RARA/RARα(retinoic acid receptor,alpha)antagonist.AR7 specifically activates chaperone-mediated-autophagy(CMA)activity without affecting macroautophagy. | price> |
R-AC-0019 | TiO2/RGO aerogel | TiO2/RGO aerogel;Titanium dioxide/RGO aerogel from ruixi. The preparation method and application belong to the technical fields of material preparation and environmental purification. Using cysteine as the reducing agent and cross-linking agent, TiO2 is loaded on RGO airgel through a simple one-step hydrothermal method for the first time to form TiO2/RGO airgel. The gel has a macrostructure of 2.0cm in diameter and 3.5cm in height. | price> |
R-C-1676 | SANT-1 CAS:304909-07-7 | SANT-1 is a potent,cell-permeable inhibitor of Sonic hedgehog(Shh)signaling;high affinity antagonist of smoothened activity(KD=1.2nM).Inhibits smoothened agonist effects with an IC50 of 20 nM(in Shh-LIGHT2 cells). | price> |
R-AC-0020 | PI/Ag aerogel | PI/Ag aerogel;Polyimide/Ag aerogel;PI/Argentum aerogel;Polyimide/Argentum aerogel from ruixi.PI/Ag aerogel composite photocatalytic material and its preparation method and application. The preparation method of the PI/Ag aerogel composite photocatalytic material includes: S1. Using diamine and dianhydride as reaction precursors, add AgNO3 solution , add cross-linking agent, catalyst and dehydrating agent, select reducing solvent, and prepare PI/Ag wet gel using sol-gel method; S2. After aging the wet gel prepared in step S1 in ethanol, use ethanol supercritical Technology can be obtained by drying. | price> |
R-C-1677 | PF-04418948 CAS:1078166-57-0 | PF-04418948 is a novel,potent and selective prostaglandin EP2 receptor antagonist.PF-04418948 inhibited prostaglandin E(2)(PGE(2))-induced increase in cAMP in cells expressing EP(2)receptors with a functional K(B)value of 1.8nM. | price> |
R-R-3377 | Facinicline hydrochloride CAS No.677305-02-1 | Facinicline hydrochloride (RG3487 hydrochloride)/CAS No.677305-02-1 is an orally active nicotinic α7 receptor partial agonist, with a Ki of 6 nM for α7 human nAChR. Facinicline hydrochloride (RG3487 hydrochloride) improves cognition and sensorimotor gating in rodents. Facinicline hydrochloride (RG3487 hydrochloride) shows high affinity (antagonist) to 5-HT3Rs with a Ki value of 1.2 nM. | price> |
R-C-1678 | Fosaprepitant dimeglumine CAS:265121-04-8 | Fosaprepitant dimeglumine(MK-0517)is a prodrug of Aprepitant(HY-10052). Fosaprepitant dimeglumine is a neurokinin-1 receptor antagonist,which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV). | price> |
R-R-3378 | Revexepride CAS No.219984-49-3 | Revexepride/CAS No.219984-49-3 is a highly selective 5-HT4 receptor agonist, and a potential inducer of CYP3A4 enzyme, used for the treatment of gastroesophageal reflux disease. | price> |
R-C-1679 | Tebipenem pivoxil CAS:161715-24-8 | Tebipenem pivoxil(ME1211)SPR994 and TBM-PI,is a novel oral carbapenem antibiotic.TBM-PI is a promising antibiotic for the treatment of acute otitis media.Tebipenem pivoxil displays an excellent antibacterial activity against a variety of pathogenic bacteria in vitro. | price> |
R-R-3379 | Relenopride hydrochloride CAS No.1221416-42-7 | Relenopride (YKP10811) hydrochloride/CAS No.1221416-42-7 is a specific and selective 5-HT4 receptor agonist (Ki=4.96 nM). Relenopride hydrochloride has 120-fold and 6-fold lower affinity, respectively, for 5-HT2A (Ki=600 nM) and 5-HT2B receptors (Ki=31 nM) than for 5-HT4. Relenopride hydrochloride increases gastrointestinal (GI) motility. | price> |
R-C-1680 | Carteolol hydrochloride CAS:51781-21-6 | Carteolol hydrochloride(OPC-1085 hydrochloride)is a non-selective beta blocker used to treat glaucoma. | price> |
R-R-3380 | TC-2153 CAS No.1381769-23-8 | TC-2153/CAS No.1381769-23-8 is a selective inhibitor of striatal-enriched protein tyrosine phosphatase (STEP), with psychotropic activity and low acute toxicity. TC-2153 increases the expression of brain-derived neurotropic factor (BDNF) in the brain. And it decreases MAOA and 5-HT1A receptors mRNA level in midbrain. TC-2153 also inhibits 5-HT2A receptor-mediated signaling. | price> |
R-C-1681 | 1400W dihydrochloride CAS:214358-33-5 | 1400W dihydrochloride is a potent and selective inhibitor of human inducible NO synthase with Ki values of 7nM. | price> |
R-R-3381 | (R)-Praziquantel-d11 CAS No.1399880-38-6 | (R)-Praziquantel-d11/CAS No.1399880-38-6 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer. | price> |
R-C-1682 | SQ22536 CAS:17318-31-9 | SQ22536(9-(tetrahydrofuran-2-yl)-9h-purin-6-amine)is an inhibitor of adenylyl cyclase with an IC50 of 1.4μM.It can inhibit PGE1-stimulated increases in cAMP levels in intact human platelets. | price> |
R-R-3382 | Clozapine-d8 CAS No.1185053-50-2 | Clozapine-d8/CAS No.1185053-50-2 is the deuterium labeled Clozapine. Clozapine is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors. | price> |