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Catalog	name	Description	price
R-C-1693	T0901317 CAS：293754-55-9	T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5μM,respectively.T0901317 is a dual inverse agonist of RORα and RORγ with Ki of 132 nM and 51 nM,respectively.T0901317 significantly suppresses cell proliferation and induces apoptosis.	price>
R-R-3393	Lintopride CAS No.107429-63-0	Lintopride/CAS No.107429-63-0 is a 5HT4 antagonist with moderate 5HT3 antagonist properties.	price>
R-C-1694	GSK-189254 CAS：720690-73-3	GSK189254A(GSK189254)is a novel,potent and selective histamine H3 receptor antagonist with pKi values of 9.59-9.90 and 8.51-9.17 for human and rat H3, respectively.	price>
R-R-3394	Lesopitron dihydrochloride CAS No.132449-89-9	Lesopitron dihydrochloride/CAS No.132449-89-9 is a full and selective 5-HT1A receptor agonist with IC50 of 125 nM in rat hippocampal membranes.	price>
R-C-1695	E 7449 CAS：1140964-99-3	E7449 is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2,with IC50s of 2.0,1.0,∼50 and∼50 nM for PARP1,PARP2,TNKS1 and TNKS2,respectively,using 32P-NAD+ as substrate.	price>
R-R-3395	Lidanserin CAS No.73725-85-6	Lidanserin (ZK-33839)/CAS No.73725-85-6 acts as a 5-HT2A and α1-adrenergic receptor antagonist.	price>
R-C-1696	NCB-0846 CAS：1792999-26-8	NCB-0846 is the first orally available small-molecule TNIK inhibitor,having anti-Wnt activity and suppressing Wnt-driven intestinal tumorigenesis,also inhibiting FLT3,JAK3,PDGFRa,TRKA,CDK2/CycA2,and HGK.	price>
R-R-3396	Sertindole-d4 CAS No.1794737-42-0	Sertindole-d4/CAS No.1794737-42-0 is the deuterium labeled Sertindole. Sertindole, a neuroleptic, is one of the newer antipsychotic medications available.	price>
R-C-1697	ETP-46321 CAS：1252594-99-2	ETP-46321 is a potent and orally bioavailable PI3Kα and PI3Kδ inhibitor with Kiapps of 2.3 and 14.2 nM,respectively.	price>
R-R-3397	Aripiprazole (1,1,2,2,3,3,4,4-d8) CAS No.1089115-04-7	Aripiprazole (1,1,2,2,3,3,4,4-d8)/CAS No.1089115-04-7 is the deuterium labeled Aripiprazole. Aripiprazole (OPC-14597) is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM.	price>
R-C-1698	Debio 0617B CAS:1332329-27-7	Debio-0617B is a first-in-class multi-kinase inhibitor.Debio-0617B targets pSTAT3,pSTAT5,JAK,SRC,ABL,and class III/V RTKs.	price>
R-R-3398	Paliperidone-d4 CAS No.1020719-55-4	Paliperidone-d4/CAS No.1020719-55-4 is the deuterium labeled Paliperidone. Paliperidone (9-Hydroxyrisperidone), the major active metabolite of Risperidone, is a dopamine D2 antagonist and 5-HT2A antagonist. Paliperidone is also active as an antagonist at α1 and α2 adrenergic receptors and H1-histaminergic receptors. Paliperidone, a antipsychotic agent, shows efficacy against schizophrenia.	price>
R-C-1699	SRT-2104 CAS：1093403-33-8	SRT 2104 is a first-in-class,highly selective and brain-permeable activator of the NAD+dependent deacetylase Sirt1,increases Sirt1 protein,but shows no effect on Sirt1 mRNA.Used in the research of diabetes mellitus and Huntington is disease.	price>
R-R-3399	Alverine-d5 citrate CAS No.1215327-00-6	Alverine-d5 (citrate)/CAS No.1215327-00-6 is the deuterium labeled Alverine citrate.	price>
R-C-1700	Lesinurad CAS： 878672-00-5	Lesinurad is a URAT1 and OAT inhibitor,is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2µM, respectively.	price>
R-R-3400	Trazodone-d6 hydrochloride CAS No.1181578-71-1	Trazodone-d6 (hydrochloride)/CAS No.1181578-71-1 is the deuterium labeled Trazodone hydrochloride.	price>
R-C-1701	lusutrombopag CAS：1110766-97-6	Lusutrombopag（S-888711is an orally bioavailable,small molecule thrombopoietin (TPO)receptor agonist being developed by Shionogi for chronic liver disease(CLD) patients with thrombocytopenia prior to elective invasive surgery.	price>
R-R-3401	MS 245 oxalate CAS No.275363-58-1	MS 245 oxalate/CAS No.275363-58-1 is a potent antagonist of 5-HT6 receptor with a Ki of 2 nM.	price>
R-C-1702	Granisetron CAS：109889-09-0	Granisetron(Sancuso,Kevatril,Granisetronum,Sustol)is a serotonin receptor(5HT-3 selective)antagonist that is used as an antiemetic and antinauseant for cancer chemotherapy.	price>
R-R-3402	Blonanserin-d5 CAS No.1346599-86-7	Blonanserin-d5/CAS No.1346599-86-7 is a deuterium labeled Blonanserin. Blonanserin is a dopamine D2/5-HT2 receptor antagonist and an atypical antipsychotic.	price>

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