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Catalog	name	Description	price
R-C-1872	JNJ7706621 CAS:443797-96-4	JNJ-7706621 is pan-CDK inhibitor with the highest potency on CDK1/2 with IC50 of 9 nM/4nM and showing >6-fold selectivity for CDK1/2 than CDK3/4/6 in cell-free assays.It also potently inhibits Aurora A/B and has no activity on Plk1 and Wee1.	price>
R-R-3572	Theobromine-d3 CAS No.65566-69-0	Theobromine-d3/CAS No.65566-69-0 is the deuterium labeled Theobromine. Theobromine is a methylxanthine found in cacao beans which can inhibit adenosine receptor A1 (AR1) signaling.	price>
R-C-1873	Mc-MMAE CAS:863971-24-8	Mc-MMAE is a protective group(maleimidocaproyl)-conjugated monomethyl auristatin E(MMAE),which is a potent tubulin inhibitor.Mc-MMAE is a drug-linker conjugate for ADC.	price>
R-R-3573	KFM19 CAS No.133058-72-7	KFM19/CAS No.133058-72-7 is a potent, selective Adenosine receptor (A1-receptor) antagonist, with an IC50 of 50 nM.	price>
R-C-1874	IPI3063 CAS:1425043-73-7	IPI-3063 is a Selective Phosphoinoside-3-Kinase p110δInhibitor.IPI-3063 Potently Suppresses B Cell Survival,Proliferation,and Differentiation.IPI-3063 is a highly potent molecule useful for studying p110δ function in immune cells.	price>
R-R-3574	PSB-1115 CAS No.152529-79-8	PSB-1115/CAS No.152529-79-8 is a selective A2B Adenosine Receptor antagonist. PSB-1115 inhibits the 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced contraction inhibition of acetylcholine (ACh).	price>
R-C-1875	BAM7 CAS:331244-89-4	BAM7 is a direct and selective activator of proapoptotic BAX with an IC50 of 3.3μM.	price>
R-R-3575	GP531 CAS No.142344-87-4	GP531/CAS No.142344-87-4 is a potent, second-generation adenosine regulating agent, is pharmacologically silent under basal conditions but increases localized endogenous adenosine during ischemia.	price>
R-C-1876	BTSA 1 CAS:314761-14-3	BTSA1 is a pharmacologically optimized BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis.It effectively promotes apoptosis in leukemia cell lines and patient samples while sparing healthy cells.	price>
R-R-3576	Adenosine receptor antagonist 3 CAS No.2400864-80-2	Adenosine receptor antagonist 3/CAS No.2400864-80-2 is a potent antagonist of adenosine receptor. Adenosine receptor antagonist 3 has the potential for the research of cancer disease (extracted from patent WO2019233994A1, compound 1).	price>
R-C-1877	Ziritaxestat (GLPG1690) CAS:1628260-79-6	Ziritaxestat(GLPG1690)is a first-in-class autotaxin(ATX)inhibitor,with an IC50 of 131 nM and Ki of 15nnM.	price>
R-R-3577	Inupadenant hydrochloride CAS No.2411004-22-1	Inupadenant (EOS-850) hydrochloride/CAS No.2411004-22-1 is an orally active, highly selective A2A receptor antagonist. Inupadenant hydrochloride is not brain-penetrant. Inupadenant hydrochloride has potent anti-tumor activity.	price>
R-C-1878	AZD-7594 CAS:1196509-60-0	AZD-7594(AZ13189620)is an inhaled selective glucocorticoid receptor(GCCR)modulator.AZD-7594 is in phase II clinical trials by AstraZeneca for the treatment of mild to moderate asthma.It is also in phase I clinical trials for the treatment of chronic obstructive pulmonary disorder(COPD).	price>
R-R-3578	Sipagladenant CAS No.858979-50-7	Sipagladenant (Compound I)/CAS No.858979-50-7 is an orally active adenosine receptor A2A inverse agonist. Sipagladenant can be used in frontal lobe dysfunction research.	price>
R-C-1879	KPT9274 CAS:1643913-93-2	KPT 9274(ATG-019)is an orally bioavailable small molecule that is a non-competitive dual inhibitor of PAK4 and NAMPT.It shows an IC50 of~120nM for NAMPT in a cell-free enzymatic assay.	price>
R-R-3579	SDZ-WAG994 CAS No.130714-47-5	SDZ-WAG994 (WAG-994)/CAS No.130714-47-5 is a stable, long-acting, selective and orally active A1-adenosine receptor agonist with a KD of 23 nM. SDZ-WAG994 can be used for the research of atrial fibrillation.	price>
R-C-1880	LX-2343 CAS:333745-53-2	LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM.LX2343 acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23μM.LX2343 stimulates autophagy in its promotion of Aβ clearance.	price>
R-R-3580	Alloxazine CAS No.490-59-5	Alloxazine/CAS No.490-59-5 is a selective A2b antagonist. Alloxazine completely block 5 N-Ethylcarboxamido adenosine (NECA)-mediated cyclic AMP accumulation with an IC50 of 2.9 μM. Alloxazine can be used for the research of cancer.	price>
R-C-1881	ML355 CAS:1532593-30-8	ML355 is a potent and selective inhibitor of 12-Lipoxygenase(12-LOX)with an IC50 of 0.34μM,shows excellent selectivity over related lipoxygenases and cyclooxygenases,and possesses favorable ADME properties.	price>
R-R-3581	ST 1535 CAS No.496955-42-1	ST 1535/CAS No.496955-42-1 is a potent and orally active A2A adenosine receptor antagonist. ST 1535 shows antiparkinsonian activity and antitremorigenic effects. ST 1535 has the potential for the research of Parkinson disease.	price>

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