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Catalog	name	Description	price
R-C-1882	Evobrutinib (M-2951) CAS:1415823-73-2	Evobrutinib(M-2951,MSC-2364447C)is a highly selective BTK inhibitor with an IC50 of 37.9 nM.It has potential anti-neoplastic activity.	price>
R-R-3582	Binodenoson CAS No.144348-08-3	Binodenoson (MRE-0470)/CAS No.144348-08-3 is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stress imaging.	price>
R-C-1883	SSR240612 CAS:464930-42-5	SSR240612 is a potent,and orally active specific non-peptide bradykinin B1 receptor antagonist,with Kis of 0.48 nM and 0.73nM for B1 kinin receptors of human fibroblast MRC5 and HEK cells expressing human B1 receptors,481nM and 358 nM for B2 receptors of guinea pig ileum membranes and CHO cells expressing human B1 receptor,respectively.	price>
R-R-3583	CL 316243 CAS No.138908-40-4	CL316243/CAS No.138908-40-4 is a highly potent selective β3-adrenoceptor agonist with a EC50 of 3 nM, but is an extremely poor to β1/2- receptors.CL316243 is a effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate. CL316243 has the potential for the treatment obesity, diabetes and urge urinary incontinence.	price>
R-C-1884	FH1(BRD-K4477) CAS： 2719-05-3	FH1(NSC 12407)enhances hepatocyte functions,and promotes the differentiation of induced pluripotent stem(iPS)-derived hepatocytes toward a phenotype more mature and the maturation of well-differentiated cultures of hepatocyte-like cells (iHeps).	price>
R-R-3584	Propranolol CAS No.525-66-6	Propranolol/CAS No.525-66-6 is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively. Propranolol inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM. Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy.	price>
R-C-1885	Saquinavir mesylate CAS：149845-06-7	Saquinavir mesylate is an HIV Protease Inhibitor used in antiretroviral therapy.	price>
R-R-3585	Zenidolol hydrochloride CAS No.72795-01-8	Zenidolol (ICI-118551) hydrochloride/CAS No.72795-01-8 is a highly selective β2 adrenergic receptor antagonist, with Kis of 0.7, 49.5 and 611 nM for β2, β1 and β3 receptors, respectively.	price>
R-C-1886	Crenigacestat (LY3039478) CAS：1421438-81-4	LY3039478 is a orally bioavailable,novel small molecule Notch inhibitor with an IC50 of ~1nM in most of the tumor cell lines tested.	price>
R-R-3586	BRL-44408 maleate CAS No.681806-46-2	BRL-44408 maleate/CAS No.681806-46-2 is an α2A-adrenoceptor antagonist (Ki: 8.5 nM). BRL-44408 maleate has antidepressant and analgesic activity. BRL-44408 also improves cecal ligation puncture (CLP)-induced acute lung injury.	price>
R-C-1887	Opaganib (ABC294640) CAS：915385-81-8	ABC294640 is an orally available,aryladamantane compound and selective inhibitor of sphingosine kinase-2(SK2)with potential antineoplastic activity.	price>
R-R-3587	Adenosine receptor antagonist 4 CAS No.133240-06-9	Adenosine receptor antagonist 4 (compound 2)/CAS No.133240-06-9 is an adenosine A1 receptor antagonist with a Ki of 101 nM for human A1 receptor.	price>
R-C-1888	CB-03-01 CAS：19608-29-8	Clascoterone(Winlevi,Cortexolone 17 alpha-propionate,Cortexolone 17α-propionate, CB-03-01)is a topical and peripherally selective antagonist of androgen receptor(AR).	price>
R-R-3588	FSCPX CAS No.156547-56-7	FSCPX/CAS No.156547-56-7 is a potent and selective irreversible antagonist of A1 adenosine receptor (A1AR), with low nanomolar potency for binding to the A1AR. FSCPX could modify the effect of NBTI, a nucleoside transport inhibitor, by reducing the interstitial adenosine level in the guinea pig atrium.	price>
R-C-1889	Sapacitabine CAS：151823-14-2	Sapacitabine is hydrolyzed by amidases to the deoxycytosine analogue CNDAC(2-Cyano-2-deoxyarabinofuranosylcytosine),which is then phosphorylated into the active triphosphate form.As an analogue of deoxycytidine triphosphate,CNDAC triphosphate incorporates into DNA strands during replication,resulting in single-stranded DNA breaks during polymerization due to beta-elimination during the fidelity checkpoint process; cell cycle arrest in the G2 phase and apoptosis ensue.	price>
R-R-3589	Salmeterol CAS No.89365-50-4	Salmeterol (GR33343X)/CAS No.89365-50-4 is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively.	price>
R-C-1890	Pritelivir (BAY 57-1293） CAS：348086-71-5	BAY 57-1293 is a potent helicase primase inhibitor.BAY 57-1293 inhibits replication of herpes simplex virus(HSV)type 1 and type 2 in the nanomolar range in vitro by abrogating the enzymatic activity of the viral primase-helicase complex.	price>
R-R-3590	Phenylacetylglycine CAS No.500-98-1	Phenylacetylglycine/CAS No.500-98-1 is a gut microbial metabolite that can activate β2AR. Phenylacetylglycine protects against cardiac injury caused by ischemia/reperfusion.	price>
R-C-1891	Acalabrutinib（ACP-196） CAS:1420477-60-6	Acalabrutinib(ACP-196)is a selective second-generation Bruton is tyrosine kinase(BTK)inhibitor with an IC50 of 3nM,which prevents the activation of the B-cell antigen receptor(BCR)signaling pathway.ACP-196 has improved target specificity over ibrutinib with 323-,94-,19-and 9-fold selectivity over the other TEC kinase family members(ITK,TXK,BMX,and TEC,respectively)and no activity against EGFR.	price>
R-C-2251	Resibufogenin CAS：465-39-4	Resibufogenin(Bufogenin,Recibufogenin),a component of huachansu with anticancer effect,triggers necroptosis through upregulating receptor-interacting protein kinase 3(RIP3)and phosphorylating mixed lineage kinase domain-like protein at Ser358.Resibufogenin exerts cytotoxic effect by inducing reactive oxygen species(ROS)accumulation.Resibufogenin induces apoptosis and caspase-3 and caspase-8 activity.	price>

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